Russian Journal of General Chemistry

, том 89 , издание 6 , страницы 1169-1176

Synthesis and Biological Activity of 4,5,6,7-Tetrahydro-2H-indazole Derivatives

V L Gein ¹

A N Yankin ²

N V Nosova ¹

E B Levandovskaya ¹

V V Novikova ¹

I. P. Rudakova ¹

Скрыть аффилиации авторов Показать аффилиации авторов: 2 аффилиации

Perm State Pharmaceutical Academy, Perm, Russia |

St. Petersburg state University, St. Petersburg, Russia |

Тип публикации: Journal Article

Дата публикации: 2019-06-01

Pleiades Publishing

Russian Journal of General Chemistry

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SJR: 0.179

CiteScore: 1.4

Impact factor: 0.8

ISSN: 10703632, 16083350

DOI: 10.1134/S1070363219060112

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General Chemistry

Краткое описание

Novel 4,5,6,7-tetrahydro-2H-indazole derivatives were obtained via the reaction of N1,N3,2-triaryl-6-hydroxy-6-methyl-4-oxocyclohexane-1,3-dicarboxamides with hydrazine hydrate. The reaction of 4-oxocyclo-hexane-1,3-dicarboxamides with phenylhydrazine led to the formation of hydrazones instead of indazoles. The synthesized compounds were tested for antimicrobial, analgesic and anti-inflammatory activities

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Active methylene compounds

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Russian Journal of General Chemistry	Russian Journal of General Chemistry, 2, 50% Russian Journal of General Chemistry 2 публикации, 50%
Drug Development Research	Drug Development Research, 1, 25% Drug Development Research 1 публикация, 25%
Handbook of Research on Diverse Applications of Nanotechnology in Biomedicine, Chemistry, and Engineering	Handbook of Research on Diverse Applications of Nanotechnology in Biomedicine, Chemistry, and Engineering, 1, 25% Handbook of Research on Diverse Applications of Nanotechnology in Biomedicine, Chemistry, and Engineering 1 публикация, 25%
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Gein V. L. et al. Synthesis and Biological Activity of 4,5,6,7-Tetrahydro-2H-indazole Derivatives // Russian Journal of General Chemistry. 2019. Vol. 89. No. 6. pp. 1169-1176.

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Gein V. L., Yankin A. N., Nosova N. V., Levandovskaya E. B., Novikova V. V., Rudakova I. P. Synthesis and Biological Activity of 4,5,6,7-Tetrahydro-2H-indazole Derivatives // Russian Journal of General Chemistry. 2019. Vol. 89. No. 6. pp. 1169-1176.

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TY - JOUR

DO - 10.1134/S1070363219060112

UR - https://doi.org/10.1134/S1070363219060112

TI - Synthesis and Biological Activity of 4,5,6,7-Tetrahydro-2H-indazole Derivatives

T2 - Russian Journal of General Chemistry

AU - Gein, V L

AU - Yankin, A N

AU - Nosova, N V

AU - Levandovskaya, E B

AU - Novikova, V V

AU - Rudakova, I. P.

PY - 2019

DA - 2019/06/01

PB - Pleiades Publishing

SP - 1169-1176

IS - 6

VL - 89

SN - 1070-3632

SN - 1608-3350

ER -

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@article{2019_Gein,

author = {V L Gein and A N Yankin and N V Nosova and E B Levandovskaya and V V Novikova and I. P. Rudakova},

title = {Synthesis and Biological Activity of 4,5,6,7-Tetrahydro-2H-indazole Derivatives},

journal = {Russian Journal of General Chemistry},

year = {2019},

volume = {89},

publisher = {Pleiades Publishing},

month = {jun},

url = {https://doi.org/10.1134/S1070363219060112},

number = {6},

pages = {1169--1176},

doi = {10.1134/S1070363219060112}

}

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Gein, V. L., et al. “Synthesis and Biological Activity of 4,5,6,7-Tetrahydro-2H-indazole Derivatives.” Russian Journal of General Chemistry, vol. 89, no. 6, Jun. 2019, pp. 1169-1176. https://doi.org/10.1134/S1070363219060112.