Synthesis and Biological Activity of 4,5,6,7-Tetrahydro-2H-indazole Derivatives
Publication type: Journal Article
Publication date: 2019-06-01
scimago Q4
wos Q4
SJR: 0.179
CiteScore: 1.4
Impact factor: 0.8
ISSN: 10703632, 16083350
General Chemistry
Abstract
Novel 4,5,6,7-tetrahydro-2H-indazole derivatives were obtained via the reaction of N1,N3,2-triaryl-6-hydroxy-6-methyl-4-oxocyclohexane-1,3-dicarboxamides with hydrazine hydrate. The reaction of 4-oxocyclo-hexane-1,3-dicarboxamides with phenylhydrazine led to the formation of hydrazones instead of indazoles. The synthesized compounds were tested for antimicrobial, analgesic and anti-inflammatory activities
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Gein V. L. et al. Synthesis and Biological Activity of 4,5,6,7-Tetrahydro-2H-indazole Derivatives // Russian Journal of General Chemistry. 2019. Vol. 89. No. 6. pp. 1169-1176.
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Gein V. L., Yankin A. N., Nosova N. V., Levandovskaya E. B., Novikova V. V., Rudakova I. P. Synthesis and Biological Activity of 4,5,6,7-Tetrahydro-2H-indazole Derivatives // Russian Journal of General Chemistry. 2019. Vol. 89. No. 6. pp. 1169-1176.
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RIS
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TY - JOUR
DO - 10.1134/S1070363219060112
UR - https://doi.org/10.1134/S1070363219060112
TI - Synthesis and Biological Activity of 4,5,6,7-Tetrahydro-2H-indazole Derivatives
T2 - Russian Journal of General Chemistry
AU - Gein, V L
AU - Yankin, A N
AU - Nosova, N V
AU - Levandovskaya, E B
AU - Novikova, V V
AU - Rudakova, I. P.
PY - 2019
DA - 2019/06/01
PB - Pleiades Publishing
SP - 1169-1176
IS - 6
VL - 89
SN - 1070-3632
SN - 1608-3350
ER -
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BibTex (up to 50 authors)
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@article{2019_Gein,
author = {V L Gein and A N Yankin and N V Nosova and E B Levandovskaya and V V Novikova and I. P. Rudakova},
title = {Synthesis and Biological Activity of 4,5,6,7-Tetrahydro-2H-indazole Derivatives},
journal = {Russian Journal of General Chemistry},
year = {2019},
volume = {89},
publisher = {Pleiades Publishing},
month = {jun},
url = {https://doi.org/10.1134/S1070363219060112},
number = {6},
pages = {1169--1176},
doi = {10.1134/S1070363219060112}
}
Cite this
MLA
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Gein, V. L., et al. “Synthesis and Biological Activity of 4,5,6,7-Tetrahydro-2H-indazole Derivatives.” Russian Journal of General Chemistry, vol. 89, no. 6, Jun. 2019, pp. 1169-1176. https://doi.org/10.1134/S1070363219060112.
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