Molecular Biology, volume 57, issue 1, pages 1-6

Interleukin-11 in Pathologies of the Nervous System

Publication typeJournal Article
Publication date2023-02-01
Quartile SCImago
Q4
Quartile WOS
Q4
Impact factor1.2
ISSN00268933, 16083245
Structural Biology
Biophysics
Abstract
The study of the role of cytokines in various pathological conditions of the body is a topical area in modern biomedicine. Understanding the physiological roles played by cytokines will aid in finding applications for them as pharmacological agents in clinical practice. Interleukin 11 (IL-11) was discovered in 1990 in fibrocyte-like bone marrow stromal cells, but there has been increased interest in this cytokine in recent years. IL-11 has been shown to correct inflammatory pathways in the epithelial tissues of the respiratory system, where the main events occur during SARS-CoV-2 infection. Further research in this direction will probably support the use of this cytokine in clinical practice. The cytokine plays a significant role in the central nervous system; local expression by nerve cells has been shown. Studies show the involvement of IL-11 in the mechanisms of development of a number of pathologies of the nervous system, and therefore it seems relevant to generalize and analyze the experimental data obtained in this direction. This review summarizes information that shows the involvement of IL-11 in the mechanisms of development of brain pathologies. In the near future this cytokine will likely find clinical application for the correction of mechanisms that are involved in the formation of pathological conditions of the nervous system.

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GOST Copy
Airapetov M. I. et al. Interleukin-11 in Pathologies of the Nervous System // Molecular Biology. 2023. Vol. 57. No. 1. pp. 1-6.
GOST all authors (up to 50) Copy
Airapetov M. I., Eresko S. O., Ignatova P. D., LEBEDEV A. A., Bychkov E. R., Shabanov P. D. Interleukin-11 in Pathologies of the Nervous System // Molecular Biology. 2023. Vol. 57. No. 1. pp. 1-6.
RIS |
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RIS Copy
TY - JOUR
DO - 10.1134/s0026893323010028
UR - https://doi.org/10.1134%2Fs0026893323010028
TI - Interleukin-11 in Pathologies of the Nervous System
T2 - Molecular Biology
AU - Airapetov, M I
AU - Eresko, S O
AU - Ignatova, P. D.
AU - LEBEDEV, A. A.
AU - Bychkov, E R
AU - Shabanov, P D
PY - 2023
DA - 2023/02/01 00:00:00
PB - Pleiades Publishing
SP - 1-6
IS - 1
VL - 57
SN - 0026-8933
SN - 1608-3245
ER -
BibTex |
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BibTex Copy
@article{2023_Airapetov,
author = {M I Airapetov and S O Eresko and P. D. Ignatova and A. A. LEBEDEV and E R Bychkov and P D Shabanov},
title = {Interleukin-11 in Pathologies of the Nervous System},
journal = {Molecular Biology},
year = {2023},
volume = {57},
publisher = {Pleiades Publishing},
month = {feb},
url = {https://doi.org/10.1134%2Fs0026893323010028},
number = {1},
pages = {1--6},
doi = {10.1134/s0026893323010028}
}
MLA
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MLA Copy
Airapetov, M. I., et al. “Interleukin-11 in Pathologies of the Nervous System.” Molecular Biology, vol. 57, no. 1, Feb. 2023, pp. 1-6. https://doi.org/10.1134%2Fs0026893323010028.
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