Russian Journal of Genetics, volume 60, issue 11, pages 1504-1515

Differential Expression of Skeletal Muscle Sites and Fast and Slow Muscle Fibers in Mongolian Horses

Z. Jia 1
T. Bou 1
W. Ding 1
X. Ren 1
H. Liu 1
W. Gong 1
H. Hu 1
L. Shi 1
M. Dugarjaviin 1
D. Bai 1
Show full list: 10 authors
1
 
Inner Mongolia Key Laboratory of Equine Science Research and Technology Innovation; Scientific Observing and Experimental Station of Equine Genetics, Breeding and Reproduction, Ministry of Agriculture and Rural Affairs; Equine Research Center, College of Animal Science, Inner Mongolia Agricultural University, Hohhot, China
Publication typeJournal Article
Publication date2024-11-25
scimago Q4
wos Q4
SJR0.185
CiteScore1.0
Impact factor0.6
ISSN10227954, 16083369
Abstract
Mongolian horses are characterized by strong endurance in sports and their meat is a special food resource in Inner Mongolia, China. To assess the characteristics of the Mongolian horses in terms of exercise and meat quality, in this study, we selected healthy and untrained adult stallions and collected a total of 24 skeletal muscles from representative parts of the whole body (head and neck, forelimb, trunk, abdominal wall side, and hindlimb) for transcriptome sequencing. After grouping by site, using RNA-Sequencing (RNA-Seq) data, differential expression analysis between two sites was performed to obtain the differentially expressed genes (DEGs) between different skeletal muscle sites, and the up-regulated DEGs at each site were pooled and enriched to obtain the relevant genes and pathways specific to each skeletal muscle site. The semimembranosus and gastrocnemius were selected from the hindlimb for phenotypic studies of fast and slow muscle fibers as well as RNA-Seq analysis. We found that the semimembranosus had 71.69% of slow muscle fibers and 124 up-regulated DEGs. The gastrocnemius had 78.93% of fast muscle fibers and 31 up-regulated DEGs. The results showed that the biochemical properties of horse skeletal muscle were altered by site and the percentage of fast and slow muscle fibers in the skeletal muscle.
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