Finger-Actuated Microfluidic Platform for Colorimetric Isothermal Diagnostics of Neisseria meningitidis and Herpes Simplex Virus
Publication type: Journal Article
Publication date: 2024-04-09
scimago Q4
wos Q3
SJR: 0.267
CiteScore: 1.9
Impact factor: 1.7
ISSN: 10681620, 1608330X, 15739163
Organic Chemistry
Biochemistry
Abstract
Objective: The 2020 pandemic showed a need for quick, accessible, and user-friendly diagnostic tests to detect various pathogens applicable at the point-of-care (POC) or at home. Such diagnostics should require a minimum of steps and equipment. Results and Discussion: In this study, we have manufactured and modified a one-way valve system for the microfluidic platform and integrate it to the device for DNA extraction and loop-mediated isothermal amplification (LAMP) with a color readout which allowed rapid and effective diagnosis of Neisseria meningitidis (N. meningitidis) and herpes simplex virus (HSV) without the use of expensive equipment. The article describes the aspects of the manufacturing process and a possible presentation of the platform. Conclusions: This article presents a solution of integrating of embedded flexible films with ion-dependent colorimetric visualization.
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Total citations:
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Citations from 2024:
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Shkodenko L. A. et al. Finger-Actuated Microfluidic Platform for Colorimetric Isothermal Diagnostics of Neisseria meningitidis and Herpes Simplex Virus // Russian Journal of Bioorganic Chemistry. 2024. Vol. 50. No. 2. pp. 544-553.
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Shkodenko L. A., Laushkina V. O., Rubel M. S., Sergeeva E. Finger-Actuated Microfluidic Platform for Colorimetric Isothermal Diagnostics of Neisseria meningitidis and Herpes Simplex Virus // Russian Journal of Bioorganic Chemistry. 2024. Vol. 50. No. 2. pp. 544-553.
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TY - JOUR
DO - 10.1134/s106816202411044x
UR - https://link.springer.com/10.1134/S106816202411044X
TI - Finger-Actuated Microfluidic Platform for Colorimetric Isothermal Diagnostics of Neisseria meningitidis and Herpes Simplex Virus
T2 - Russian Journal of Bioorganic Chemistry
AU - Shkodenko, L. A.
AU - Laushkina, V. O.
AU - Rubel, M. S.
AU - Sergeeva, E.
PY - 2024
DA - 2024/04/09
PB - Pleiades Publishing
SP - 544-553
IS - 2
VL - 50
SN - 1068-1620
SN - 1608-330X
SN - 1573-9163
ER -
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BibTex (up to 50 authors)
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@article{2024_Shkodenko,
author = {L. A. Shkodenko and V. O. Laushkina and M. S. Rubel and E. Sergeeva},
title = {Finger-Actuated Microfluidic Platform for Colorimetric Isothermal Diagnostics of Neisseria meningitidis and Herpes Simplex Virus},
journal = {Russian Journal of Bioorganic Chemistry},
year = {2024},
volume = {50},
publisher = {Pleiades Publishing},
month = {apr},
url = {https://link.springer.com/10.1134/S106816202411044X},
number = {2},
pages = {544--553},
doi = {10.1134/s106816202411044x}
}
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MLA
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Shkodenko, L. A., et al. “Finger-Actuated Microfluidic Platform for Colorimetric Isothermal Diagnostics of Neisseria meningitidis and Herpes Simplex Virus.” Russian Journal of Bioorganic Chemistry, vol. 50, no. 2, Apr. 2024, pp. 544-553. https://link.springer.com/10.1134/S106816202411044X.
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