Pleiades Publishing
Russian Journal of General Chemistry
,  volume 89 ,  issue 9 ,  pages 1744-1751

Synthesis and Properties of New Fluorine-Containing Thieno[2,3-b]pyridine Derivatives

Publication type: Journal Article
Publication date: 2019-09-01
Pleiades Publishing
scimago Q4
wos Q4
SJR: 0.179
CiteScore: 1.4
Impact factor: 0.8
ISSN: 10703632, 16083350
General Chemistry
Abstract
Cyanothioacetamide reacted with 1,1,5,5-tetrafluoroacetylacetone to give 4,6-bis(difluoromethyl)-2-thioxo-1,2-dihydropyridine-3-carbonitrile, and alkylation of the latter with α-chloroacetamides afforded 3-amino-4,6-bis(difluoromethyl)thieno[2,3-b]pyridine-2-carboxamides. The structure of the key compounds was proved using two-dimensional NMR techniques. In silico analysis of potential biological activity and bioavailability of the synthesized compounds was performed.
Found 
Found 
6 citations
Dotsenko Viktor
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N.D. Zelinsky Institute of Organic Chemistry of the Russian Academy of Sciences
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A.N. Frumkin Institute of Physical Chemistry and Electrochemistry of the Russian Academy of Sciences
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Volcho Konstantin
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A.E. Arbuzov Institute of Organic and Physical Chemistry of the Kazan Scientific Center of the Russian Academy of Sciences
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GOST Copy
Buryi D. S. et al. Synthesis and Properties of New Fluorine-Containing Thieno[2,3-b]pyridine Derivatives // Russian Journal of General Chemistry. 2019. Vol. 89. No. 9. pp. 1744-1751.
GOST all authors (up to 50) Copy
Buryi D. S., Dotsenko V. V., Aksenov N. A., Aksenova I. V. Synthesis and Properties of New Fluorine-Containing Thieno[2,3-b]pyridine Derivatives // Russian Journal of General Chemistry. 2019. Vol. 89. No. 9. pp. 1744-1751.
RIS |
Cite this
RIS Copy
TY - JOUR
DO - 10.1134/s1070363219090032
UR - https://doi.org/10.1134/s1070363219090032
TI - Synthesis and Properties of New Fluorine-Containing Thieno[2,3-b]pyridine Derivatives
T2 - Russian Journal of General Chemistry
AU - Buryi, D S
AU - Dotsenko, V V
AU - Aksenov, N A
AU - Aksenova, I V
PY - 2019
DA - 2019/09/01
PB - Pleiades Publishing
SP - 1744-1751
IS - 9
VL - 89
SN - 1070-3632
SN - 1608-3350
ER -
BibTex |
Cite this
BibTex (up to 50 authors) Copy
@article{2019_Buryi,
author = {D S Buryi and V V Dotsenko and N A Aksenov and I V Aksenova},
title = {Synthesis and Properties of New Fluorine-Containing Thieno[2,3-b]pyridine Derivatives},
journal = {Russian Journal of General Chemistry},
year = {2019},
volume = {89},
publisher = {Pleiades Publishing},
month = {sep},
url = {https://doi.org/10.1134/s1070363219090032},
number = {9},
pages = {1744--1751},
doi = {10.1134/s1070363219090032}
}
MLA
Cite this
MLA Copy
Buryi, D. S., et al. “Synthesis and Properties of New Fluorine-Containing Thieno[2,3-b]pyridine Derivatives.” Russian Journal of General Chemistry, vol. 89, no. 9, Sep. 2019, pp. 1744-1751. https://doi.org/10.1134/s1070363219090032.