Synthesis and Regiospecific Bromination of (2E,4E)-5-Aryl-2-(4-arylthiazol-2-yl)penta-2,4-dienenitrile
N A Pakholka
1
,
V V Dotsenko
2, 3
,
B S Krivokolysko
4
,
K A Frolov
1, 4
,
N A Aksenov
3
,
I V Aksenova
3
,
S V Shcherbakov
3
,
S N Ovcharov
3
,
S G Krivokolysko
1, 4
1
Laboratory “KhimEx”, V. Dahl Lugansk State University, Lugansk, Ukraine
|
Publication type: Journal Article
Publication date: 2021-04-01
scimago Q4
wos Q4
SJR: 0.179
CiteScore: 1.4
Impact factor: 0.8
ISSN: 10703632, 16083350
General Chemistry
Abstract
The reaction of (2E,4E)-5-phenyl-2-cyano-2,4-pentadienethioamide or (E)-3-(2-nitrophenyl)acrolein and cyanothioacetamide with α-bromoketones afforded new (2E,4E)-5-aryl-2-(4-arylthiazol-2-yl)penta-2,4-dienenitriles. Direct bromination of the latter by the action of bromine in DMF proceeded regiospecifically at the C5 position of the thiazole ring without affecting the diene system and leads to the formation of new series of (2E,4E)-5-aryl-2-(5-bromo-4-arylthiazol-2-yl)penta-2,4-dienenitriles.
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12
Total citations:
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Citations from 2024:
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(66.67%)
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GOST
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Pakholka N. A. et al. Synthesis and Regiospecific Bromination of (2E,4E)-5-Aryl-2-(4-arylthiazol-2-yl)penta-2,4-dienenitrile // Russian Journal of General Chemistry. 2021. Vol. 91. No. 4. pp. 606-613.
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Pakholka N. A., Dotsenko V. V., Krivokolysko B. S., Frolov K. A., Aksenov N. A., Aksenova I. V., Shcherbakov S. V., Ovcharov S. N., Krivokolysko S. G. Synthesis and Regiospecific Bromination of (2E,4E)-5-Aryl-2-(4-arylthiazol-2-yl)penta-2,4-dienenitrile // Russian Journal of General Chemistry. 2021. Vol. 91. No. 4. pp. 606-613.
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RIS
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TY - JOUR
DO - 10.1134/s1070363221040058
UR - https://doi.org/10.1134/s1070363221040058
TI - Synthesis and Regiospecific Bromination of (2E,4E)-5-Aryl-2-(4-arylthiazol-2-yl)penta-2,4-dienenitrile
T2 - Russian Journal of General Chemistry
AU - Pakholka, N A
AU - Dotsenko, V V
AU - Krivokolysko, B S
AU - Frolov, K A
AU - Aksenov, N A
AU - Aksenova, I V
AU - Shcherbakov, S V
AU - Ovcharov, S N
AU - Krivokolysko, S G
PY - 2021
DA - 2021/04/01
PB - Pleiades Publishing
SP - 606-613
IS - 4
VL - 91
SN - 1070-3632
SN - 1608-3350
ER -
Cite this
BibTex (up to 50 authors)
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@article{2021_Pakholka,
author = {N A Pakholka and V V Dotsenko and B S Krivokolysko and K A Frolov and N A Aksenov and I V Aksenova and S V Shcherbakov and S N Ovcharov and S G Krivokolysko},
title = {Synthesis and Regiospecific Bromination of (2E,4E)-5-Aryl-2-(4-arylthiazol-2-yl)penta-2,4-dienenitrile},
journal = {Russian Journal of General Chemistry},
year = {2021},
volume = {91},
publisher = {Pleiades Publishing},
month = {apr},
url = {https://doi.org/10.1134/s1070363221040058},
number = {4},
pages = {606--613},
doi = {10.1134/s1070363221040058}
}
Cite this
MLA
Copy
Pakholka, N. A., et al. “Synthesis and Regiospecific Bromination of (2E,4E)-5-Aryl-2-(4-arylthiazol-2-yl)penta-2,4-dienenitrile.” Russian Journal of General Chemistry, vol. 91, no. 4, Apr. 2021, pp. 606-613. https://doi.org/10.1134/s1070363221040058.