Pseudo-Five-Component Stereoselective Synthesis of Highly Functionalized 3-Azabicyclo[3.3.1]nona-2,7-dienes
Publication type: Journal Article
Publication date: 2021-05-01
scimago Q4
wos Q4
SJR: 0.179
CiteScore: 1.4
Impact factor: 0.8
ISSN: 10703632, 16083350
General Chemistry
Abstract
The reaction of aromatic aldehydes with malononitrile, ethyl or butyl cyanoacetate and acetylacetone in the presence of NaOH under mild conditions (EtOH, 25°C) led to the formation of new series of (1S,5R,6R,9R)/(1R,5S,6S,9S)-2-amino-6,9-diaryl-7-acetyl-8-methyl-4-oxo-5-cyano-3-azabicyclo[3.3.1]nona-2,7-diene-1-carboxylic acids esters. A plausible mechanism of the cascade reaction was proposed.
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Ismiyev A. I. et al. Pseudo-Five-Component Stereoselective Synthesis of Highly Functionalized 3-Azabicyclo[3.3.1]nona-2,7-dienes // Russian Journal of General Chemistry. 2021. Vol. 91. No. 5. pp. 758-767.
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Ismiyev A. I., Dotsenko V. V., Aksenov N. A., Aksenova I. V., Magarramov A. M. Pseudo-Five-Component Stereoselective Synthesis of Highly Functionalized 3-Azabicyclo[3.3.1]nona-2,7-dienes // Russian Journal of General Chemistry. 2021. Vol. 91. No. 5. pp. 758-767.
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TY - JOUR
DO - 10.1134/s1070363221050029
UR - https://doi.org/10.1134/s1070363221050029
TI - Pseudo-Five-Component Stereoselective Synthesis of Highly Functionalized 3-Azabicyclo[3.3.1]nona-2,7-dienes
T2 - Russian Journal of General Chemistry
AU - Ismiyev, A I
AU - Dotsenko, V V
AU - Aksenov, N A
AU - Aksenova, I V
AU - Magarramov, A M
PY - 2021
DA - 2021/05/01
PB - Pleiades Publishing
SP - 758-767
IS - 5
VL - 91
SN - 1070-3632
SN - 1608-3350
ER -
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@article{2021_Ismiyev,
author = {A I Ismiyev and V V Dotsenko and N A Aksenov and I V Aksenova and A M Magarramov},
title = {Pseudo-Five-Component Stereoselective Synthesis of Highly Functionalized 3-Azabicyclo[3.3.1]nona-2,7-dienes},
journal = {Russian Journal of General Chemistry},
year = {2021},
volume = {91},
publisher = {Pleiades Publishing},
month = {may},
url = {https://doi.org/10.1134/s1070363221050029},
number = {5},
pages = {758--767},
doi = {10.1134/s1070363221050029}
}
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Ismiyev, A. I., et al. “Pseudo-Five-Component Stereoselective Synthesis of Highly Functionalized 3-Azabicyclo[3.3.1]nona-2,7-dienes.” Russian Journal of General Chemistry, vol. 91, no. 5, May. 2021, pp. 758-767. https://doi.org/10.1134/s1070363221050029.