Hydrolysis of Substituted 3-(Thien-2-yl)imino-3H-furan-2-ones and Anti-Inflammatory Activity of the Reaction Products
Publication type: Journal Article
Publication date: 2021-10-01
scimago Q4
wos Q4
SJR: 0.179
CiteScore: 1.4
Impact factor: 0.8
ISSN: 10703632, 16083350
General Chemistry
Abstract
The hydrolysis of substituted 3-(thien-2-yl)imino-3H-furan-2-ones in the presence of trifluoroacetic acid afforded a series of substituted 4-oxo-2-thienylaminobut-2-enoic acids. Anti-inflammatory activity and acute toxicity of the obtained substituted 4-oxo-2-thienylaminobut-2-enoic acids were studied. It was found that the obtained compounds have a pronounced anti-inflammatory activity and low toxicity.
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Shipilovskikh D. A. et al. Hydrolysis of Substituted 3-(Thien-2-yl)imino-3H-furan-2-ones and Anti-Inflammatory Activity of the Reaction Products // Russian Journal of General Chemistry. 2021. Vol. 91. No. 10. pp. 2025-2030.
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Shipilovskikh D. A., Makhmudov R. R., Rubtsov A. E., Shipilovskikh S. A. Hydrolysis of Substituted 3-(Thien-2-yl)imino-3H-furan-2-ones and Anti-Inflammatory Activity of the Reaction Products // Russian Journal of General Chemistry. 2021. Vol. 91. No. 10. pp. 2025-2030.
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TY - JOUR
DO - 10.1134/s1070363221100157
UR - https://doi.org/10.1134/s1070363221100157
TI - Hydrolysis of Substituted 3-(Thien-2-yl)imino-3H-furan-2-ones and Anti-Inflammatory Activity of the Reaction Products
T2 - Russian Journal of General Chemistry
AU - Shipilovskikh, D A
AU - Makhmudov, R R
AU - Rubtsov, Aleksandr E
AU - Shipilovskikh, Sergei A
PY - 2021
DA - 2021/10/01
PB - Pleiades Publishing
SP - 2025-2030
IS - 10
VL - 91
SN - 1070-3632
SN - 1608-3350
ER -
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BibTex (up to 50 authors)
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@article{2021_Shipilovskikh,
author = {D A Shipilovskikh and R R Makhmudov and Aleksandr E Rubtsov and Sergei A Shipilovskikh},
title = {Hydrolysis of Substituted 3-(Thien-2-yl)imino-3H-furan-2-ones and Anti-Inflammatory Activity of the Reaction Products},
journal = {Russian Journal of General Chemistry},
year = {2021},
volume = {91},
publisher = {Pleiades Publishing},
month = {oct},
url = {https://doi.org/10.1134/s1070363221100157},
number = {10},
pages = {2025--2030},
doi = {10.1134/s1070363221100157}
}
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MLA
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Shipilovskikh, D. A., et al. “Hydrolysis of Substituted 3-(Thien-2-yl)imino-3H-furan-2-ones and Anti-Inflammatory Activity of the Reaction Products.” Russian Journal of General Chemistry, vol. 91, no. 10, Oct. 2021, pp. 2025-2030. https://doi.org/10.1134/s1070363221100157.