New Heterocyclisation Reactions of 5-Amino-3-(cyanomethyl)-1H-pyrazole-4-carbonitrile with Some 1,3-Dielectrophilic Agents
Publication type: Journal Article
Publication date: 2022-03-01
scimago Q4
wos Q4
SJR: 0.179
CiteScore: 1.4
Impact factor: 0.8
ISSN: 10703632, 16083350
General Chemistry
Abstract
5-Amino-3-(cyanomethyl)-1H-pyrazole-4-carbonitrile enters into condensation reactions with β-diketones and dibenzalacetone to form 2-(cyanomethyl)pyrazolo[1,5-a]pyrimidine-3-carbonitrile derivatives. The reaction with cyanoguanidine in an acid medium leads to the formation of 2,4-diamino-7-(cyanomethyl)pyrazolo[1,5-a][1,3,5]triazine-8-carbonitrile. Structure of the obtained compounds was confirmed by spectral data, as well as the results of a quantum chemical study of possible reaction routes for the reaction of 5-amino-3-(cyanomethyl)-1H-pyrazole-4-carbonitrile with benzoyltrifluoroacetone. Bioavailability parameters were predicted for the obtained products in silico, and possible protein targets were predicted by protein-ligand docking.
Found
Nothing found, try to update filter.
Found
Nothing found, try to update filter.
Top-30
Journals
|
1
2
3
|
|
|
Russian Journal of General Chemistry
3 publications, 50%
|
|
|
Russian Chemical Reviews
1 publication, 16.67%
|
|
|
Журнал Общей Химии
1 publication, 16.67%
|
|
|
Molecules
1 publication, 16.67%
|
|
|
1
2
3
|
Publishers
|
1
2
3
4
|
|
|
Pleiades Publishing
4 publications, 66.67%
|
|
|
Autonomous Non-profit Organization Editorial Board of the journal Uspekhi Khimii
1 publication, 16.67%
|
|
|
MDPI
1 publication, 16.67%
|
|
|
1
2
3
4
|
- We do not take into account publications without a DOI.
- Statistics recalculated weekly.
Are you a researcher?
Create a profile to get free access to personal recommendations for colleagues and new articles.
Metrics
7
Total citations:
7
Citations from 2024:
4
(66.67%)
Cite this
GOST |
RIS |
BibTex |
MLA
Cite this
GOST
Copy
Semenova A. M. et al. New Heterocyclisation Reactions of 5-Amino-3-(cyanomethyl)-1H-pyrazole-4-carbonitrile with Some 1,3-Dielectrophilic Agents // Russian Journal of General Chemistry. 2022. Vol. 92. No. 3. pp. 367-382.
GOST all authors (up to 50)
Copy
Semenova A. M., Gadzhiakhmedova Ya. R., Bespalov A. V., Dotsenko V. V., Aksenov N. A., Aksenova I. V. New Heterocyclisation Reactions of 5-Amino-3-(cyanomethyl)-1H-pyrazole-4-carbonitrile with Some 1,3-Dielectrophilic Agents // Russian Journal of General Chemistry. 2022. Vol. 92. No. 3. pp. 367-382.
Cite this
RIS
Copy
TY - JOUR
DO - 10.1134/s1070363222030057
UR - https://doi.org/10.1134/s1070363222030057
TI - New Heterocyclisation Reactions of 5-Amino-3-(cyanomethyl)-1H-pyrazole-4-carbonitrile with Some 1,3-Dielectrophilic Agents
T2 - Russian Journal of General Chemistry
AU - Semenova, A M
AU - Gadzhiakhmedova, Ya R
AU - Bespalov, A V
AU - Dotsenko, Viktor V
AU - Aksenov, Nicolai A.
AU - Aksenova, Inna V.
PY - 2022
DA - 2022/03/01
PB - Pleiades Publishing
SP - 367-382
IS - 3
VL - 92
SN - 1070-3632
SN - 1608-3350
ER -
Cite this
BibTex (up to 50 authors)
Copy
@article{2022_Semenova,
author = {A M Semenova and Ya R Gadzhiakhmedova and A V Bespalov and Viktor V Dotsenko and Nicolai A. Aksenov and Inna V. Aksenova},
title = {New Heterocyclisation Reactions of 5-Amino-3-(cyanomethyl)-1H-pyrazole-4-carbonitrile with Some 1,3-Dielectrophilic Agents},
journal = {Russian Journal of General Chemistry},
year = {2022},
volume = {92},
publisher = {Pleiades Publishing},
month = {mar},
url = {https://doi.org/10.1134/s1070363222030057},
number = {3},
pages = {367--382},
doi = {10.1134/s1070363222030057}
}
Cite this
MLA
Copy
Semenova, A. M., et al. “New Heterocyclisation Reactions of 5-Amino-3-(cyanomethyl)-1H-pyrazole-4-carbonitrile with Some 1,3-Dielectrophilic Agents.” Russian Journal of General Chemistry, vol. 92, no. 3, Mar. 2022, pp. 367-382. https://doi.org/10.1134/s1070363222030057.