volume 45 issue 8 pages 1219-1223

Synthesis and dehydrogenation of spinaceamine and spinacine 4-hetaryl derivatives

Publication typeJournal Article
Publication date2009-08-01
scimago Q4
wos Q4
SJR0.190
CiteScore1.3
Impact factor0.9
ISSN10704280, 16083393
Organic Chemistry
Abstract
The reaction of histamine and histidine with various hetarylaldehydes under the conditions of the base-catalyzed Pictet-Spengler process affords 4-hetaryl-substituted derivatives of spinaceamine and spinacine. The dehydrogenation of the 4-hetaryl-substituted spinaceamine derivatives using elemental sulfur in DMF at 120–130°C led to the formation of 4-hetaryl derivatives of imidazo[4,5-c]-pyridine. Under similar conditions the 4-hetaryl-substituted spinacine derivatives suffered both the dehydrogenation and oxidative decarboxylation resulting in the products identical to the compounds obtained by the dehydrogenation of 4-hetaryl-substituted spinaceamine.
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GOST Copy
Smolyar N. N. et al. Synthesis and dehydrogenation of spinaceamine and spinacine 4-hetaryl derivatives // Russian Journal of Organic Chemistry. 2009. Vol. 45. No. 8. pp. 1219-1223.
GOST all authors (up to 50) Copy
Smolyar N. N., Abramyants M. G., Zavyazkina T. I., Matveeva D. I., Borodkin Ya. S., Voloskii I. A. Synthesis and dehydrogenation of spinaceamine and spinacine 4-hetaryl derivatives // Russian Journal of Organic Chemistry. 2009. Vol. 45. No. 8. pp. 1219-1223.
RIS |
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RIS Copy
TY - JOUR
DO - 10.1134/s1070428009080181
UR - https://doi.org/10.1134/s1070428009080181
TI - Synthesis and dehydrogenation of spinaceamine and spinacine 4-hetaryl derivatives
T2 - Russian Journal of Organic Chemistry
AU - Smolyar, N N
AU - Abramyants, M G
AU - Zavyazkina, T I
AU - Matveeva, D I
AU - Borodkin, Ya S
AU - Voloskii, I A
PY - 2009
DA - 2009/08/01
PB - Pleiades Publishing
SP - 1219-1223
IS - 8
VL - 45
SN - 1070-4280
SN - 1608-3393
ER -
BibTex |
Cite this
BibTex (up to 50 authors) Copy
@article{2009_Smolyar,
author = {N N Smolyar and M G Abramyants and T I Zavyazkina and D I Matveeva and Ya S Borodkin and I A Voloskii},
title = {Synthesis and dehydrogenation of spinaceamine and spinacine 4-hetaryl derivatives},
journal = {Russian Journal of Organic Chemistry},
year = {2009},
volume = {45},
publisher = {Pleiades Publishing},
month = {aug},
url = {https://doi.org/10.1134/s1070428009080181},
number = {8},
pages = {1219--1223},
doi = {10.1134/s1070428009080181}
}
MLA
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MLA Copy
Smolyar, N. N., et al. “Synthesis and dehydrogenation of spinaceamine and spinacine 4-hetaryl derivatives.” Russian Journal of Organic Chemistry, vol. 45, no. 8, Aug. 2009, pp. 1219-1223. https://doi.org/10.1134/s1070428009080181.