volume 59 issue 7 pages 1149-1157

Synthesis and Properties of N,N′-Disubstituted Ureas Containing Adamantane and Pyridine (Quinoline) Fragments

Publication typeJournal Article
Publication date2023-07-01
scimago Q4
wos Q4
SJR0.190
CiteScore1.3
Impact factor0.9
ISSN10704280, 16083393
Organic Chemistry
Abstract
A series of N,N′-disubstituted ureas containing a pyridine or quinoline fragment and a lipophilic adamantane moiety (13 examples, 53–94% yield) have been synthesized by the reaction of N,N-dimethyl-N′-(pyridin-2-yl or quinoline-2-yl)ureas with amine hydrochlorides. The synthesized compounds differed from each other by the position of substitution in the adamantane fragment, structure of the alkyl linker between the adamantane fragment and amide group, and heterocyclic substituent. They are potential target-oriented inhibitors of human soluble epoxide hydrolase (sEH).
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Kasatkina S. O. et al. Synthesis and Properties of N,N′-Disubstituted Ureas Containing Adamantane and Pyridine (Quinoline) Fragments // Russian Journal of Organic Chemistry. 2023. Vol. 59. No. 7. pp. 1149-1157.
GOST all authors (up to 50) Copy
Kasatkina S. O., Baykov S. V., Petrov A. A., Burmistrov V., Boyarskiy V. P. Synthesis and Properties of N,N′-Disubstituted Ureas Containing Adamantane and Pyridine (Quinoline) Fragments // Russian Journal of Organic Chemistry. 2023. Vol. 59. No. 7. pp. 1149-1157.
RIS |
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RIS Copy
TY - JOUR
DO - 10.1134/s1070428023070059
UR - https://doi.org/10.1134/s1070428023070059
TI - Synthesis and Properties of N,N′-Disubstituted Ureas Containing Adamantane and Pyridine (Quinoline) Fragments
T2 - Russian Journal of Organic Chemistry
AU - Kasatkina, Svetlana O.
AU - Baykov, Sergey V
AU - Petrov, A. A.
AU - Burmistrov, Vladimir
AU - Boyarskiy, Vadim P
PY - 2023
DA - 2023/07/01
PB - Pleiades Publishing
SP - 1149-1157
IS - 7
VL - 59
SN - 1070-4280
SN - 1608-3393
ER -
BibTex |
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BibTex (up to 50 authors) Copy
@article{2023_Kasatkina,
author = {Svetlana O. Kasatkina and Sergey V Baykov and A. A. Petrov and Vladimir Burmistrov and Vadim P Boyarskiy},
title = {Synthesis and Properties of N,N′-Disubstituted Ureas Containing Adamantane and Pyridine (Quinoline) Fragments},
journal = {Russian Journal of Organic Chemistry},
year = {2023},
volume = {59},
publisher = {Pleiades Publishing},
month = {jul},
url = {https://doi.org/10.1134/s1070428023070059},
number = {7},
pages = {1149--1157},
doi = {10.1134/s1070428023070059}
}
MLA
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MLA Copy
Kasatkina, Svetlana O., et al. “Synthesis and Properties of N,N′-Disubstituted Ureas Containing Adamantane and Pyridine (Quinoline) Fragments.” Russian Journal of Organic Chemistry, vol. 59, no. 7, Jul. 2023, pp. 1149-1157. https://doi.org/10.1134/s1070428023070059.