Synthesis and Properties of N,N′-Disubstituted Ureas and Their Isosteric Analogs Containing Polycyclic Fragments: XVIII. N-[2-(Adamantan-2-yl)ethyl]-N′-R-ureas and -Thioureas
Publication type: Journal Article
Publication date: 2024-01-01
scimago Q4
wos Q4
SJR: 0.190
CiteScore: 1.3
Impact factor: 0.9
ISSN: 10704280, 16083393
Abstract
Methods have been developed for the synthesis of N-[2-(adamantan-2-yl)ethyl]-N′-R-ureas and -thioureas in 36–87% yields by the reaction of 2-(adamantan-2-yl)ethanamine with aromatic isocyanates and isothiocyanates. The displacement of the ethylene bridge from position 1 to position 2 of the adamantane fragment has been found to exert no significant effect on the logP values and melting points of the corresponding ureas.
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Russian Journal of Organic Chemistry
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Pleiades Publishing
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Burmistrov V. et al. Synthesis and Properties of N,N′-Disubstituted Ureas and Their Isosteric Analogs Containing Polycyclic Fragments: XVIII. N-[2-(Adamantan-2-yl)ethyl]-N′-R-ureas and -Thioureas // Russian Journal of Organic Chemistry. 2024. Vol. 60. No. 1. pp. 12-17.
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Burmistrov V., Zapravdina D. M., Savelyev E. N., Orlinson B. S., Butov G. M., Novakov I. A. Synthesis and Properties of N,N′-Disubstituted Ureas and Their Isosteric Analogs Containing Polycyclic Fragments: XVIII. N-[2-(Adamantan-2-yl)ethyl]-N′-R-ureas and -Thioureas // Russian Journal of Organic Chemistry. 2024. Vol. 60. No. 1. pp. 12-17.
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TY - JOUR
DO - 10.1134/s1070428024010020
UR - https://link.springer.com/10.1134/S1070428024010020
TI - Synthesis and Properties of N,N′-Disubstituted Ureas and Their Isosteric Analogs Containing Polycyclic Fragments: XVIII. N-[2-(Adamantan-2-yl)ethyl]-N′-R-ureas and -Thioureas
T2 - Russian Journal of Organic Chemistry
AU - Burmistrov, Vladimir
AU - Zapravdina, D. M.
AU - Savelyev, E N
AU - Orlinson, Boris S
AU - Butov, Gennady M.
AU - Novakov, I A
PY - 2024
DA - 2024/01/01
PB - Pleiades Publishing
SP - 12-17
IS - 1
VL - 60
SN - 1070-4280
SN - 1608-3393
ER -
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@article{2024_Burmistrov,
author = {Vladimir Burmistrov and D. M. Zapravdina and E N Savelyev and Boris S Orlinson and Gennady M. Butov and I A Novakov},
title = {Synthesis and Properties of N,N′-Disubstituted Ureas and Their Isosteric Analogs Containing Polycyclic Fragments: XVIII. N-[2-(Adamantan-2-yl)ethyl]-N′-R-ureas and -Thioureas},
journal = {Russian Journal of Organic Chemistry},
year = {2024},
volume = {60},
publisher = {Pleiades Publishing},
month = {jan},
url = {https://link.springer.com/10.1134/S1070428024010020},
number = {1},
pages = {12--17},
doi = {10.1134/s1070428024010020}
}
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MLA
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Burmistrov, Vladimir, et al. “Synthesis and Properties of N,N′-Disubstituted Ureas and Their Isosteric Analogs Containing Polycyclic Fragments: XVIII. N-[2-(Adamantan-2-yl)ethyl]-N′-R-ureas and -Thioureas.” Russian Journal of Organic Chemistry, vol. 60, no. 1, Jan. 2024, pp. 12-17. https://link.springer.com/10.1134/S1070428024010020.