Synthesis and Antioxidant Activity of Furan Derivatives Containing a 1,3,4-Oxadiazole Ring
Publication type: Journal Article
Publication date: 2024-04-01
scimago Q4
wos Q4
SJR: 0.190
CiteScore: 1.3
Impact factor: 0.9
ISSN: 10704280, 16083393
Abstract
Methyl 5-aminomethylfuran-2-carboxylates reacted with methylamine to give 5-aminomethylN-methylfuran-2-carboxamides, and their hydrolysis afforded the corresponding carboxylic acids. The reaction of methyl 5-aminomethylfuran-2-carboxylates with hydrazine hydrate produced hydrazides which were acylated with benzoyl or 2-furoyl chloride and then subjected to heterocyclization to obtain furan derivatives containing a 1,3,4-oxadiazole ring. The target products were also synthesized in one step by reacting 5-aminomethylfuran-2-carbohydrazides with acid chlorides in the presence of phosphoryl chloride.
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Russian Journal of General Chemistry
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Aghekyan A. A. et al. Synthesis and Antioxidant Activity of Furan Derivatives Containing a 1,3,4-Oxadiazole Ring // Russian Journal of Organic Chemistry. 2024. Vol. 60. No. 4. pp. 655-663.
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Aghekyan A. A., Panosyan H. A., Buniatyan Z. M., Muradyan R. E., Mkryan G. G. Synthesis and Antioxidant Activity of Furan Derivatives Containing a 1,3,4-Oxadiazole Ring // Russian Journal of Organic Chemistry. 2024. Vol. 60. No. 4. pp. 655-663.
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TY - JOUR
DO - 10.1134/s1070428024040146
UR - https://link.springer.com/10.1134/S1070428024040146
TI - Synthesis and Antioxidant Activity of Furan Derivatives Containing a 1,3,4-Oxadiazole Ring
T2 - Russian Journal of Organic Chemistry
AU - Aghekyan, A A
AU - Panosyan, H A
AU - Buniatyan, Zh. M.
AU - Muradyan, R E
AU - Mkryan, G G
PY - 2024
DA - 2024/04/01
PB - Pleiades Publishing
SP - 655-663
IS - 4
VL - 60
SN - 1070-4280
SN - 1608-3393
ER -
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@article{2024_Aghekyan,
author = {A A Aghekyan and H A Panosyan and Zh. M. Buniatyan and R E Muradyan and G G Mkryan},
title = {Synthesis and Antioxidant Activity of Furan Derivatives Containing a 1,3,4-Oxadiazole Ring},
journal = {Russian Journal of Organic Chemistry},
year = {2024},
volume = {60},
publisher = {Pleiades Publishing},
month = {apr},
url = {https://link.springer.com/10.1134/S1070428024040146},
number = {4},
pages = {655--663},
doi = {10.1134/s1070428024040146}
}
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MLA
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Aghekyan, A. A., et al. “Synthesis and Antioxidant Activity of Furan Derivatives Containing a 1,3,4-Oxadiazole Ring.” Russian Journal of Organic Chemistry, vol. 60, no. 4, Apr. 2024, pp. 655-663. https://link.springer.com/10.1134/S1070428024040146.