Biochemistry (Moscow), volume 74, issue 12, pages 1350-1355
Microbial origin of phenylcarboxylic acids in the human body
Publication type: Journal Article
Publication date: 2009-12-01
Journal:
Biochemistry (Moscow)
Quartile SCImago
Q2
Quartile WOS
Q3
Impact factor: 2.8
ISSN: 00062979, 16083040
Biochemistry
General Medicine
Abstract
In previous studies we demonstrated increased amounts of phenylcarboxylic acids (PCA) in serum of patients with sepsis. This observation prompted the present study of the ability of the human microbiome bacteria to produce PCA in vitro. PCA were detected in culture media by gas chromatography-mass spectrometry. Increased amounts of phenyllactic and p-hydroxyphenyllactic acids were produced by Klebsiella pneumonia, Escherichia coli, and Staphylococcus aureus. Certain strict anaerobes (bifidobacteria, lactobacteria, eubacteria) have also been found to actively produce these PCA, but these bacteria are not etiologically linked to sepsis. Thus our results demonstrate the ability of sepsis-related bacteria to produce PCA and provide experimental support for the theory that the accumulation of PCA in the blood of patients with sepsis results from microbial degradation of phenylalanine and tyrosine.
Top-30
Citations by journals
|
1
2
3
4
|
|
|
Journal of Analytical Chemistry
4 publications, 9.52%
|
|
|
Metabolites
3 publications, 7.14%
|
|
|
Critical Care
3 publications, 7.14%
|
|
|
Molecules
2 publications, 4.76%
|
|
|
Russian Chemical Reviews
2 publications, 4.76%
|
|
|
Shock
1 publication, 2.38%
|
|
|
Animals
1 publication, 2.38%
|
|
|
Journal of Personalized Medicine
1 publication, 2.38%
|
|
|
Frontiers in Molecular Biosciences
1 publication, 2.38%
|
|
|
Journal of Genetics and Genomics
1 publication, 2.38%
|
|
|
Journal of Breath Research
1 publication, 2.38%
|
|
|
Clinical Mass Spectrometry
1 publication, 2.38%
|
|
|
Current Opinion in Immunology
1 publication, 2.38%
|
|
|
Journal of Critical Care
1 publication, 2.38%
|
|
|
Biomedical Chromatography
1 publication, 2.38%
|
|
|
Journal of Agricultural and Food Chemistry
1 publication, 2.38%
|
|
|
Biochemistry (Moscow)
1 publication, 2.38%
|
|
|
Current Research in Nutrition and Food Science
1 publication, 2.38%
|
|
|
American Journal of Physiology - Gastrointestinal and Liver Physiology
1 publication, 2.38%
|
|
|
Obshchaya Reanimatologiya
1 publication, 2.38%
|
|
|
Biomarkers in Toxicology
1 publication, 2.38%
|
|
|
Phytochemicals in Agriculture and Food [Working Title]
1 publication, 2.38%
|
|
|
Biochimica et Biophysica Acta - Molecular Basis of Disease
1 publication, 2.38%
|
|
|
Zhurnal «Patologicheskaia fiziologiia i eksperimental`naia terapiia»
1 publication, 2.38%
|
|
|
Journal of Proteome Research
1 publication, 2.38%
|
|
|
Microbiome Research Reports
1 publication, 2.38%
|
|
|
1
2
3
4
|
Citations by publishers
|
1
2
3
4
5
6
7
|
|
|
Multidisciplinary Digital Publishing Institute (MDPI)
7 publications, 16.67%
|
|
|
Elsevier
5 publications, 11.9%
|
|
|
Pleiades Publishing
5 publications, 11.9%
|
|
|
Springer Nature
4 publications, 9.52%
|
|
|
Autonomous Non-profit Organization Editorial Board of the journal Uspekhi Khimii
2 publications, 4.76%
|
|
|
American Chemical Society (ACS)
2 publications, 4.76%
|
|
|
Wolters Kluwer Health
1 publication, 2.38%
|
|
|
Frontiers Media S.A.
1 publication, 2.38%
|
|
|
IOP Publishing
1 publication, 2.38%
|
|
|
Wiley
1 publication, 2.38%
|
|
|
Enviro Research Publishers
1 publication, 2.38%
|
|
|
Cold Spring Harbor Laboratory
1 publication, 2.38%
|
|
|
American Physiological Society
1 publication, 2.38%
|
|
|
V. A. Negovsky Research Institute of General Reanimatology
1 publication, 2.38%
|
|
|
IntechOpen
1 publication, 2.38%
|
|
|
Cifra Ltd - Russian Agency for Digital Standardization (RADS)
1 publication, 2.38%
|
|
|
OAE Publishing Inc.
1 publication, 2.38%
|
|
|
1
2
3
4
5
6
7
|
- We do not take into account publications without a DOI.
- Statistics recalculated only for publications connected to researchers, organizations and labs registered on the platform.
- Statistics recalculated weekly.
{"yearsCitations":{"type":"bar","data":{"show":true,"labels":[2012,2013,2014,2015,2016,2017,2018,2019,2020,2021,2022,2023,2024],"ids":[0,0,0,0,0,0,0,0,0,0,0,0,0],"codes":[0,0,0,0,0,0,0,0,0,0,0,0,0],"imageUrls":["","","","","","","","","","","","",""],"datasets":[{"label":"Citations number","data":[2,0,1,2,1,3,5,3,6,7,5,2,5],"backgroundColor":["#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6"],"percentage":["4.76",0,"2.38","4.76","2.38","7.14","11.9","7.14","14.29","16.67","11.9","4.76","11.9"],"barThickness":null}]},"options":{"indexAxis":"x","maintainAspectRatio":true,"scales":{"y":{"ticks":{"precision":0,"autoSkip":false,"font":{"family":"Montserrat"},"color":"#000000"},"stacked":false},"x":{"ticks":{"stepSize":1,"precision":0,"font":{"family":"Montserrat"},"color":"#000000"},"stacked":false}},"plugins":{"legend":{"position":"top","labels":{"font":{"family":"Montserrat"},"color":"#000000"}},"title":{"display":true,"text":"Citations per year","font":{"size":24,"family":"Montserrat","weight":600},"color":"#000000"}}}},"journals":{"type":"bar","data":{"show":true,"labels":["Journal of Analytical Chemistry","Metabolites","Critical Care","Molecules","Russian Chemical Reviews","Shock","Animals","Journal of Personalized Medicine","Frontiers in Molecular Biosciences","Journal of Genetics and Genomics","Journal of Breath Research","Clinical Mass Spectrometry","Current Opinion in Immunology","Journal of Critical Care","Biomedical Chromatography","Journal of Agricultural and Food Chemistry","Biochemistry (Moscow)","Current Research in Nutrition and Food Science","American Journal of Physiology - Gastrointestinal and Liver Physiology","Obshchaya Reanimatologiya","Biomarkers in Toxicology","Phytochemicals in Agriculture and Food [Working Title]","Biochimica et Biophysica Acta - Molecular Basis of Disease","Zhurnal \u00abPatologicheskaia fiziologiia i eksperimental`naia terapiia\u00bb","Journal of Proteome Research","Microbiome Research Reports"],"ids":[21398,17024,11069,1770,23802,7578,7774,2479,3133,7249,4240,12018,2521,5401,1016,22576,2119,24878,20721,18491,63251,42730,15106,56434,14208,64885],"codes":[0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0],"imageUrls":["\/storage\/images\/resized\/oZgeErrVFhuDksyqFURLvYS1wtVSBWczh001igGo_medium.webp","\/storage\/images\/resized\/MjH1ITP7lMYGxeqUZfkt2BnVLgjkk413jwBV97XX_medium.webp","\/storage\/images\/resized\/voXLqlsvTwv5p3iMQ8Dhs95nqB4AXOG7Taj7G4ra_medium.webp","\/storage\/images\/resized\/MjH1ITP7lMYGxeqUZfkt2BnVLgjkk413jwBV97XX_medium.webp","\/storage\/images\/resized\/9Mus3KG1Tkd7Bwaurt8H3RwWh0CxRlGoO6ng9UK1_medium.webp","\/storage\/images\/resized\/6QE8LXWrLpkoy5A2te6hw7who46GeCoTYIstuoAz_medium.webp","\/storage\/images\/resized\/MjH1ITP7lMYGxeqUZfkt2BnVLgjkk413jwBV97XX_medium.webp","\/storage\/images\/resized\/MjH1ITP7lMYGxeqUZfkt2BnVLgjkk413jwBV97XX_medium.webp","\/storage\/images\/resized\/4QWA67eqfcfyOiA8Wk7YnqroHFqQbTsmDJUYTCTg_medium.webp","\/storage\/images\/resized\/GDnYOu1UpMMfMMRV6Aqle4H0YLLsraeD9IP9qScG_medium.webp","\/storage\/images\/resized\/LsKy6OnmmmRGcAU6CZgWQvNiP1polbaSLNrN7zqj_medium.webp","\/storage\/images\/resized\/GDnYOu1UpMMfMMRV6Aqle4H0YLLsraeD9IP9qScG_medium.webp","\/storage\/images\/resized\/GDnYOu1UpMMfMMRV6Aqle4H0YLLsraeD9IP9qScG_medium.webp","\/storage\/images\/resized\/GDnYOu1UpMMfMMRV6Aqle4H0YLLsraeD9IP9qScG_medium.webp","\/storage\/images\/resized\/bRyGpdm98BkAUYiK1YFNpl5Z7hPu6Gd87gbIeuG3_medium.webp","\/storage\/images\/resized\/iLiQsFqFaSEx6chlGQ5fbAwF6VYU3WWa08hkss0g_medium.webp","\/storage\/images\/resized\/oZgeErrVFhuDksyqFURLvYS1wtVSBWczh001igGo_medium.webp","","\/storage\/images\/resized\/eZQGZ1aBN8Xm8Yr5YG7nBeNQtWLPrca5SfDreLbq_medium.webp","\/storage\/images\/resized\/dIXgZVXZ9QdQ3x3VBZzswbdEzP8zjWjWy3CRMtLp_medium.webp","\/storage\/images\/resized\/voXLqlsvTwv5p3iMQ8Dhs95nqB4AXOG7Taj7G4ra_medium.webp","","\/storage\/images\/resized\/GDnYOu1UpMMfMMRV6Aqle4H0YLLsraeD9IP9qScG_medium.webp","","\/storage\/images\/resized\/iLiQsFqFaSEx6chlGQ5fbAwF6VYU3WWa08hkss0g_medium.webp","\/storage\/images\/resized\/0oGA3odz6rRHYyWD8vQnHiPJ8KIaP1PtNoJm7RE1_medium.webp"],"datasets":[{"label":"","data":[4,3,3,2,2,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1],"backgroundColor":["#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6"],"percentage":[9.52,7.14,7.14,4.76,4.76,2.38,2.38,2.38,2.38,2.38,2.38,2.38,2.38,2.38,2.38,2.38,2.38,2.38,2.38,2.38,2.38,2.38,2.38,2.38,2.38,2.38],"barThickness":13}]},"options":{"indexAxis":"y","maintainAspectRatio":false,"scales":{"y":{"ticks":{"precision":0,"autoSkip":false,"font":{"family":"Montserrat"},"color":"#000000"},"stacked":false},"x":{"ticks":{"stepSize":null,"precision":0,"font":{"family":"Montserrat"},"color":"#000000"},"stacked":false}},"plugins":{"legend":{"position":"top","labels":{"font":{"family":"Montserrat"},"color":"#000000"}},"title":{"display":true,"text":"Journals","font":{"size":24,"family":"Montserrat","weight":600},"color":"#000000"}}}},"publishers":{"type":"bar","data":{"show":true,"labels":["Multidisciplinary Digital Publishing Institute (MDPI)","Elsevier","Pleiades Publishing","Springer Nature","Autonomous Non-profit Organization Editorial Board of the journal Uspekhi Khimii","American Chemical Society (ACS)","Wolters Kluwer Health","Frontiers Media S.A.","IOP Publishing","Wiley","Enviro Research Publishers","Cold Spring Harbor Laboratory","American Physiological Society","V. A. Negovsky Research Institute of General Reanimatology","IntechOpen","Cifra Ltd - Russian Agency for Digital Standardization (RADS)","OAE Publishing Inc."],"ids":[202,17,101,8,9422,40,32,208,2075,11,6795,6909,166,5301,8015,7219,7181],"codes":[0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0],"imageUrls":["\/storage\/images\/resized\/MjH1ITP7lMYGxeqUZfkt2BnVLgjkk413jwBV97XX_medium.webp","\/storage\/images\/resized\/GDnYOu1UpMMfMMRV6Aqle4H0YLLsraeD9IP9qScG_medium.webp","\/storage\/images\/resized\/oZgeErrVFhuDksyqFURLvYS1wtVSBWczh001igGo_medium.webp","\/storage\/images\/resized\/voXLqlsvTwv5p3iMQ8Dhs95nqB4AXOG7Taj7G4ra_medium.webp","\/storage\/images\/resized\/9Mus3KG1Tkd7Bwaurt8H3RwWh0CxRlGoO6ng9UK1_medium.webp","\/storage\/images\/resized\/iLiQsFqFaSEx6chlGQ5fbAwF6VYU3WWa08hkss0g_medium.webp","\/storage\/images\/resized\/6QE8LXWrLpkoy5A2te6hw7who46GeCoTYIstuoAz_medium.webp","\/storage\/images\/resized\/4QWA67eqfcfyOiA8Wk7YnqroHFqQbTsmDJUYTCTg_medium.webp","\/storage\/images\/resized\/LsKy6OnmmmRGcAU6CZgWQvNiP1polbaSLNrN7zqj_medium.webp","\/storage\/images\/resized\/bRyGpdm98BkAUYiK1YFNpl5Z7hPu6Gd87gbIeuG3_medium.webp","","\/storage\/images\/resized\/hg4jJjT8wVGtHstBCc0zk465Mg9pLx3G4odCDOqE_medium.webp","\/storage\/images\/resized\/eZQGZ1aBN8Xm8Yr5YG7nBeNQtWLPrca5SfDreLbq_medium.webp","\/storage\/images\/resized\/dIXgZVXZ9QdQ3x3VBZzswbdEzP8zjWjWy3CRMtLp_medium.webp","","","\/storage\/images\/resized\/0oGA3odz6rRHYyWD8vQnHiPJ8KIaP1PtNoJm7RE1_medium.webp"],"datasets":[{"label":"","data":[7,5,5,4,2,2,1,1,1,1,1,1,1,1,1,1,1],"backgroundColor":["#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6"],"percentage":[16.67,11.9,11.9,9.52,4.76,4.76,2.38,2.38,2.38,2.38,2.38,2.38,2.38,2.38,2.38,2.38,2.38],"barThickness":13}]},"options":{"indexAxis":"y","maintainAspectRatio":false,"scales":{"y":{"ticks":{"precision":0,"autoSkip":false,"font":{"family":"Montserrat"},"color":"#000000"},"stacked":false},"x":{"ticks":{"stepSize":null,"precision":0,"font":{"family":"Montserrat"},"color":"#000000"},"stacked":false}},"plugins":{"legend":{"position":"top","labels":{"font":{"family":"Montserrat"},"color":"#000000"}},"title":{"display":true,"text":"Publishers","font":{"size":24,"family":"Montserrat","weight":600},"color":"#000000"}}}},"yearsCitationsQuartiles":{"type":"bar","data":{"show":true,"labels":[2012,2013,2014,2015,2016,2017,2018,2019,2020,2021,2022,2023,2024],"ids":[],"codes":[],"imageUrls":[],"datasets":[{"label":"Q4","backgroundColor":"rgb(221,90,78)","data":[1,0,0,1,0,1,2,0,0,0,0,0,0],"percentage":["2.38","0","0","2.38","0","2.38","4.76","0","0","0","0","0","0"]},{"label":"Q3","backgroundColor":"rgb(251, 163,83)","data":[0,0,0,0,0,0,0,0,1,1,0,0,0],"percentage":["0","0","0","0","0","0","0","0","2.38","2.38","0","0","0"]},{"label":"Q2","backgroundColor":"rgb(232, 213, 89)","data":[0,0,0,1,0,0,0,2,0,2,1,0,0],"percentage":["0","0","0","2.38","0","0","0","4.76","0","4.76","2.38","0","0"]},{"label":"Q1","backgroundColor":"rgb(164, 207, 99)","data":[1,0,1,0,1,1,2,0,3,3,2,0,3],"percentage":["2.38","0","2.38","0","2.38","2.38","4.76","0","7.14","7.14","4.76","0","7.14"]},{"label":"Quartile not defined","backgroundColor":"#E5E7EB","data":[0,0,0,0,0,1,1,1,2,1,2,2,2],"percentage":["0","0","0","0","0","2.38","2.38","2.38","4.76","2.38","4.76","4.76","4.76"]}]},"options":{"indexAxis":"x","maintainAspectRatio":true,"scales":{"y":{"ticks":{"precision":0,"autoSkip":false,"font":{"family":"Montserrat"},"color":"#000000"},"stacked":true},"x":{"ticks":{"stepSize":1,"precision":0,"font":{"family":"Montserrat"},"color":"#000000"},"stacked":true}},"plugins":{"legend":{"position":"top","labels":{"font":{"family":"Montserrat"},"color":"#000000"}},"title":{"display":true,"text":"Citations quartiles by SCImago per year","font":{"size":24,"family":"Montserrat","weight":600},"color":"#000000"}}}},"yearsCitationsQuartilesWs":{"type":"bar","data":{"show":true,"labels":[2012,2013,2014,2015,2016,2017,2018,2019,2020,2021,2022,2023,2024],"ids":[],"codes":[],"imageUrls":[],"datasets":[{"label":"Q4","backgroundColor":"rgb(221,90,78)","data":[1,0,0,1,0,1,1,0,0,0,0,0,0],"percentage":["2.38","0","0","2.38","0","2.38","2.38","0","0","0","0","0","0"]},{"label":"Q3","backgroundColor":"rgb(251, 163,83)","data":[0,0,0,1,0,0,0,1,1,0,0,0,0],"percentage":["0","0","0","2.38","0","0","0","2.38","2.38","0","0","0","0"]},{"label":"Q2","backgroundColor":"rgb(232, 213, 89)","data":[0,0,0,0,0,0,1,2,1,3,1,0,0],"percentage":["0","0","0","0","0","0","2.38","4.76","2.38","7.14","2.38","0","0"]},{"label":"Q1","backgroundColor":"rgb(164, 207, 99)","data":[1,0,1,0,1,1,1,0,2,2,1,0,3],"percentage":["2.38","0","2.38","0","2.38","2.38","2.38","0","4.76","4.76","2.38","0","7.14"]},{"label":"Quartile not defined","backgroundColor":"#E5E7EB","data":[0,0,0,0,0,1,2,0,2,2,3,2,2],"percentage":["0","0","0","0","0","2.38","4.76","0","4.76","4.76","7.14","4.76","4.76"]}]},"options":{"indexAxis":"x","maintainAspectRatio":true,"scales":{"y":{"ticks":{"precision":0,"autoSkip":false,"font":{"family":"Montserrat"},"color":"#000000"},"stacked":true},"x":{"ticks":{"stepSize":1,"precision":0,"font":{"family":"Montserrat"},"color":"#000000"},"stacked":true}},"plugins":{"legend":{"position":"top","labels":{"font":{"family":"Montserrat"},"color":"#000000"}},"title":{"display":true,"text":"Citations quartiles by WoS per year","font":{"size":24,"family":"Montserrat","weight":600},"color":"#000000"}}}}}
Are you a researcher?
Create a profile to get free access to personal recommendations for colleagues and new articles.
Metrics
Cite this
GOST |
RIS |
BibTex |
MLA
Cite this
GOST
Copy
Beloborodov N. V. et al. Microbial origin of phenylcarboxylic acids in the human body // Biochemistry (Moscow). 2009. Vol. 74. No. 12. pp. 1350-1355.
GOST all authors (up to 50)
Copy
Beloborodov N. V., Khodakova A. S., Bairamov I. T., Olenin A. Yu. Microbial origin of phenylcarboxylic acids in the human body // Biochemistry (Moscow). 2009. Vol. 74. No. 12. pp. 1350-1355.
Cite this
RIS
Copy
TY - JOUR
DO - 10.1134/s0006297909120086
UR - https://doi.org/10.1134/s0006297909120086
TI - Microbial origin of phenylcarboxylic acids in the human body
T2 - Biochemistry (Moscow)
AU - Beloborodov, N V
AU - Khodakova, A S
AU - Bairamov, I T
AU - Olenin, A Yu
PY - 2009
DA - 2009/12/01 00:00:00
PB - Pleiades Publishing
SP - 1350-1355
IS - 12
VL - 74
SN - 0006-2979
SN - 1608-3040
ER -
Cite this
BibTex
Copy
@article{2009_Beloborodov,
author = {N V Beloborodov and A S Khodakova and I T Bairamov and A Yu Olenin},
title = {Microbial origin of phenylcarboxylic acids in the human body},
journal = {Biochemistry (Moscow)},
year = {2009},
volume = {74},
publisher = {Pleiades Publishing},
month = {dec},
url = {https://doi.org/10.1134/s0006297909120086},
number = {12},
pages = {1350--1355},
doi = {10.1134/s0006297909120086}
}
Cite this
MLA
Copy
Beloborodov, N. V., et al. “Microbial origin of phenylcarboxylic acids in the human body.” Biochemistry (Moscow), vol. 74, no. 12, Dec. 2009, pp. 1350-1355. https://doi.org/10.1134/s0006297909120086.