Biochemistry (Moscow)

, volume 87 , issue 7 , pages 590-604

Will Peptides Help to Stop COVID-19?

Viktoriya G Krut ¹

Sergei A Chuvpilo ¹

Irina V Astrakhantseva ¹

Liubov I Kozlovskaya ^{2, 3}

Grigory A. Efimov ⁴

Andrei A Kruglov ^{5, 6, 7}

Marina S. Drutskaya ^{1, 8}

Sergei A. Nedospasov ^{1, 5, 7, 8}

Hide authors affiliations Show authors affiliations: 8 affiliations

Sirius University of Science and Technology, Federal Territory Sirius, Russia |

Chumakov Federal Scientific Center for Research and Development of Immunobiological Products, Russian Academy of Sciences, Moscow, Russia |

Institute of Translational Medicine and Biotechnology, Sechenov Moscow State Medical University, Moscow, Russia |

⁴

National Medical Research Center of Hematology, Ministry of Health of the Russian Federation, Moscow, Russia |

⁵

Faculty of Biology, Lomonosov Moscow State University, Moscow, Russia |

⁶

German Rheumatism Research Center (DRFZ), Leibniz Institute, Berlin, Germany |

⁷

Belozersky Institute of Physico-chemical Biology, Lomonosov Moscow State University, Moscow, Russia |

⁸

Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, Moscow, Russia |

Publication type: Journal Article

Publication date: 2022-07-14

Pleiades Publishing

Biochemistry (Moscow)

scimago Q2

wos Q4

SJR: 0.659

CiteScore: 3.8

Impact factor: 2.2

ISSN: 00062979, 16083040

DOI: 10.1134/s0006297922070021

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PubMed ID: 36154880

Biochemistry

General Medicine

Biophysics

Geriatrics and Gerontology

Biochemistry, Genetics and Molecular Biology (miscellaneous)

Abstract

Peptides are widely used for the diagnostics, prevention, and therapy of certain human diseases. How useful can they be for the disease caused by the SARS-CoV-2 coronavirus? In this review, we discuss the possibility of using synthetic and recombinant peptides and polypeptides for prevention of COVID-19 via blocking the interaction between the virus and its main receptor ACE2, as well as components of antiviral vaccines, in particular, against new emerging virus variants.

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Krut V. G. et al. Will Peptides Help to Stop COVID-19? // Biochemistry (Moscow). 2022. Vol. 87. No. 7. pp. 590-604.

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Krut V. G., Chuvpilo S. A., Astrakhantseva I. V., Kozlovskaya L., Efimov G. A., Kruglov A. A., Drutskaya M. S., Nedospasov S. A. Will Peptides Help to Stop COVID-19? // Biochemistry (Moscow). 2022. Vol. 87. No. 7. pp. 590-604.

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