On the possibility of determination of stereological characteristics of interactions of biological micro objects with nanoparticles based on analysis of 2-dimensional images of cytological and histological specimens
A V Zhukotsky
1
,
V. I. Baranov
1
,
A V Karnaukhov
1, 2
,
N I Yakubova
1
,
E. V. Karnaukhova
2
,
O A Katkova Zhukotskaya
3
,
S A Rubchenkova
1
,
V N Karnaukhov
2
3
Research Laboratory on the Molecular Mechanisms of Aging “GeronLab”, Moscow, Russia
|
Publication type: Journal Article
Publication date: 2013-09-01
scimago Q4
SJR: 0.185
CiteScore: 1.2
Impact factor: —
ISSN: 00063509, 15556654
Biophysics
Abstract
In this article the method for studying 3-dimensional (stereological) characteristics of interactions of biological micro objects with nanoparticles on a basis of morphodensitometry analysis of standard 2-dimensional images of cytological and histological specimens is proposed. The performance of the task of determining the distance from registered nanoparticle to the center of the nucleus of the cell is described in detail. It is shown that using specific nanoparticles the results obtained may find application in science and diagnostics. Furthermore, it is possible to employ these results in nanotoxicology, in particular for determination of quantity characteristics of translocation of nanoparticles of different types in biological structures.
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Zhukotsky A. V. et al. On the possibility of determination of stereological characteristics of interactions of biological micro objects with nanoparticles based on analysis of 2-dimensional images of cytological and histological specimens // Biophysics (Russian Federation). 2013. Vol. 58. No. 5. pp. 664-668.
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Zhukotsky A. V., Baranov V. I., Karnaukhov A. V., Yakubova N. I., Karnaukhova E. V., Katkova Zhukotskaya O. A., Rubchenkova S. A., Karnaukhov V. N. On the possibility of determination of stereological characteristics of interactions of biological micro objects with nanoparticles based on analysis of 2-dimensional images of cytological and histological specimens // Biophysics (Russian Federation). 2013. Vol. 58. No. 5. pp. 664-668.
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TY - JOUR
DO - 10.1134/S0006350913050217
UR - https://doi.org/10.1134/S0006350913050217
TI - On the possibility of determination of stereological characteristics of interactions of biological micro objects with nanoparticles based on analysis of 2-dimensional images of cytological and histological specimens
T2 - Biophysics (Russian Federation)
AU - Zhukotsky, A V
AU - Baranov, V. I.
AU - Karnaukhov, A V
AU - Yakubova, N I
AU - Karnaukhova, E. V.
AU - Katkova Zhukotskaya, O A
AU - Rubchenkova, S A
AU - Karnaukhov, V N
PY - 2013
DA - 2013/09/01
PB - Pleiades Publishing
SP - 664-668
IS - 5
VL - 58
SN - 0006-3509
SN - 1555-6654
ER -
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BibTex (up to 50 authors)
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@article{2013_Zhukotsky,
author = {A V Zhukotsky and V. I. Baranov and A V Karnaukhov and N I Yakubova and E. V. Karnaukhova and O A Katkova Zhukotskaya and S A Rubchenkova and V N Karnaukhov},
title = {On the possibility of determination of stereological characteristics of interactions of biological micro objects with nanoparticles based on analysis of 2-dimensional images of cytological and histological specimens},
journal = {Biophysics (Russian Federation)},
year = {2013},
volume = {58},
publisher = {Pleiades Publishing},
month = {sep},
url = {https://doi.org/10.1134/S0006350913050217},
number = {5},
pages = {664--668},
doi = {10.1134/S0006350913050217}
}
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MLA
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Zhukotsky, A. V., et al. “On the possibility of determination of stereological characteristics of interactions of biological micro objects with nanoparticles based on analysis of 2-dimensional images of cytological and histological specimens.” Biophysics (Russian Federation), vol. 58, no. 5, Sep. 2013, pp. 664-668. https://doi.org/10.1134/S0006350913050217.