Effect of pregnancy-specific β1-glycoprotein on indoleamine-2,3-dioxygenase activity in human monocytes
Publication type: Journal Article
Publication date: 2016-07-01
scimago Q3
SJR: 0.265
CiteScore: 1.2
Impact factor: —
ISSN: 00124966, 16083105
PubMed ID:
27595833
General Biochemistry, Genetics and Molecular Biology
General Medicine
General Agricultural and Biological Sciences
General Immunology and Microbiology
Abstract
The role of heterogenic human pregnancy-specific glycoprotein (PSG), obtained by the authors’ technology, in the regulation of the indoleamine-2,3-dioxygenase (IDO) activity in female blood monocytes has been studied in vitro. PSG stimulated IDO activity under the conditions of induction of the monocytes by interferon-γ. Upon the induction of cell proliferation by lipopolysaccharides, the stimulating effect was obtained only with 10 μg/mL of PSG. Enhanced IDO activity is probably a factor of peripheral immunological tolerance and antimicrobial protection against intracellular infections in the gestation period.
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Zamorina S. A. et al. Effect of pregnancy-specific β1-glycoprotein on indoleamine-2,3-dioxygenase activity in human monocytes // Doklady Biological Sciences. 2016. Vol. 469. No. 1. pp. 206-208.
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Zamorina S. A., Timganova V. P., Bochkova M. S., Khramtsov P. V., Raev M. B. Effect of pregnancy-specific β1-glycoprotein on indoleamine-2,3-dioxygenase activity in human monocytes // Doklady Biological Sciences. 2016. Vol. 469. No. 1. pp. 206-208.
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TY - JOUR
DO - 10.1134/S0012496616040165
UR - https://doi.org/10.1134/S0012496616040165
TI - Effect of pregnancy-specific β1-glycoprotein on indoleamine-2,3-dioxygenase activity in human monocytes
T2 - Doklady Biological Sciences
AU - Zamorina, S. A.
AU - Timganova, V P
AU - Bochkova, M S
AU - Khramtsov, P V
AU - Raev, M B
PY - 2016
DA - 2016/07/01
PB - Pleiades Publishing
SP - 206-208
IS - 1
VL - 469
PMID - 27595833
SN - 0012-4966
SN - 1608-3105
ER -
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BibTex (up to 50 authors)
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@article{2016_Zamorina,
author = {S. A. Zamorina and V P Timganova and M S Bochkova and P V Khramtsov and M B Raev},
title = {Effect of pregnancy-specific β1-glycoprotein on indoleamine-2,3-dioxygenase activity in human monocytes},
journal = {Doklady Biological Sciences},
year = {2016},
volume = {469},
publisher = {Pleiades Publishing},
month = {jul},
url = {https://doi.org/10.1134/S0012496616040165},
number = {1},
pages = {206--208},
doi = {10.1134/S0012496616040165}
}
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MLA
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Zamorina, S. A., et al. “Effect of pregnancy-specific β1-glycoprotein on indoleamine-2,3-dioxygenase activity in human monocytes.” Doklady Biological Sciences, vol. 469, no. 1, Jul. 2016, pp. 206-208. https://doi.org/10.1134/S0012496616040165.
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