α-Fetoprotein Influence on the Conversion of Naïve T-Helpers into Memory T-Cell Effector Subpopulations
S. A. Zamorina
1, 2
,
V P Timganova
1
,
M S Bochkova
1
,
P V Khramtsov
1, 2
,
K A Fomicheva
2
,
M.B Rayev
1, 2, 3
,
V. A. Chereshnev
1, 2, 3
Publication type: Journal Article
Publication date: 2018-09-01
scimago Q3
SJR: 0.265
CiteScore: 1.2
Impact factor: —
ISSN: 00124966, 16083105
PubMed ID:
30402762
General Biochemistry, Genetics and Molecular Biology
General Medicine
General Agricultural and Biological Sciences
General Immunology and Microbiology
Abstract
The effect of native α-fetoprotein (AFP) on the conversion of naïve T-helpers into central memory T-cells (TCM) and effector subpopulations of the preterminally differentiated (TEM) and terminally differentiated (TEMRA) memory T-cells was studied. AFP was found to prevent the conversion of naïve T-helpers into effector subpopulations of memory T cells (TEM and TEMRA) while reducing the total production of IL-4 and IFN-γ by the studied cell populations. The data reveal a new role of AFP in the immune tolerance formation during pregnancy.
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Zamorina S. A. et al. α-Fetoprotein Influence on the Conversion of Naïve T-Helpers into Memory T-Cell Effector Subpopulations // Doklady Biological Sciences. 2018. Vol. 482. No. 1. pp. 210-213.
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Zamorina S. A., Timganova V. P., Bochkova M. S., Khramtsov P. V., Fomicheva K. A., Rayev M., Chereshnev V. A. α-Fetoprotein Influence on the Conversion of Naïve T-Helpers into Memory T-Cell Effector Subpopulations // Doklady Biological Sciences. 2018. Vol. 482. No. 1. pp. 210-213.
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TY - JOUR
DO - 10.1134/S0012496618050113
UR - https://doi.org/10.1134/S0012496618050113
TI - α-Fetoprotein Influence on the Conversion of Naïve T-Helpers into Memory T-Cell Effector Subpopulations
T2 - Doklady Biological Sciences
AU - Zamorina, S. A.
AU - Timganova, V P
AU - Bochkova, M S
AU - Khramtsov, P V
AU - Fomicheva, K A
AU - Rayev, M.B
AU - Chereshnev, V. A.
PY - 2018
DA - 2018/09/01
PB - Pleiades Publishing
SP - 210-213
IS - 1
VL - 482
PMID - 30402762
SN - 0012-4966
SN - 1608-3105
ER -
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BibTex (up to 50 authors)
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@article{2018_Zamorina,
author = {S. A. Zamorina and V P Timganova and M S Bochkova and P V Khramtsov and K A Fomicheva and M.B Rayev and V. A. Chereshnev},
title = {α-Fetoprotein Influence on the Conversion of Naïve T-Helpers into Memory T-Cell Effector Subpopulations},
journal = {Doklady Biological Sciences},
year = {2018},
volume = {482},
publisher = {Pleiades Publishing},
month = {sep},
url = {https://doi.org/10.1134/S0012496618050113},
number = {1},
pages = {210--213},
doi = {10.1134/S0012496618050113}
}
Cite this
MLA
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Zamorina, S. A., et al. “α-Fetoprotein Influence on the Conversion of Naïve T-Helpers into Memory T-Cell Effector Subpopulations.” Doklady Biological Sciences, vol. 482, no. 1, Sep. 2018, pp. 210-213. https://doi.org/10.1134/S0012496618050113.
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