Kinetics of Chemical Processes in the Human Brain. Trigger Effect and Self-Stabilization of N-Acetylaspartic Acid
Publication type: Journal Article
Publication date: 2019-02-01
scimago Q4
wos Q4
SJR: 0.195
CiteScore: 1.7
Impact factor: 1.5
ISSN: 00125016, 16083121
Physical and Theoretical Chemistry
Abstract
A kinetic model was proposed for the response of nerve tissue to an external signal stimulus. The model is based on the views of a multistep and non-linear nature of the dynamic variation of the concentrations of N-acetylaspartic acid and N-acetylaspartate in the human nerve tissue. The substrate inhibition effect in this system is a necessary factor for the self-stabilization of N-acetylaspartate as a key brain metabolite. The existence of three stationary states accounts for the trigger behavior of the system.
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Total citations:
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Citations from 2024:
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(33.34%)
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GOST
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Varfolomeev S. D. et al. Kinetics of Chemical Processes in the Human Brain. Trigger Effect and Self-Stabilization of N-Acetylaspartic Acid // Doklady Physical Chemistry. 2019. Vol. 484. No. 2. pp. 23-27.
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Varfolomeev S. D., Semenova N. A., Bykov V. I., Tsybenova S. B. Kinetics of Chemical Processes in the Human Brain. Trigger Effect and Self-Stabilization of N-Acetylaspartic Acid // Doklady Physical Chemistry. 2019. Vol. 484. No. 2. pp. 23-27.
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RIS
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TY - JOUR
DO - 10.1134/s0012501619020039
UR - https://doi.org/10.1134/s0012501619020039
TI - Kinetics of Chemical Processes in the Human Brain. Trigger Effect and Self-Stabilization of N-Acetylaspartic Acid
T2 - Doklady Physical Chemistry
AU - Varfolomeev, S. D.
AU - Semenova, N. A.
AU - Bykov, V. I.
AU - Tsybenova, S. B.
PY - 2019
DA - 2019/02/01
PB - Pleiades Publishing
SP - 23-27
IS - 2
VL - 484
SN - 0012-5016
SN - 1608-3121
ER -
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BibTex (up to 50 authors)
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@article{2019_Varfolomeev,
author = {S. D. Varfolomeev and N. A. Semenova and V. I. Bykov and S. B. Tsybenova},
title = {Kinetics of Chemical Processes in the Human Brain. Trigger Effect and Self-Stabilization of N-Acetylaspartic Acid},
journal = {Doklady Physical Chemistry},
year = {2019},
volume = {484},
publisher = {Pleiades Publishing},
month = {feb},
url = {https://doi.org/10.1134/s0012501619020039},
number = {2},
pages = {23--27},
doi = {10.1134/s0012501619020039}
}
Cite this
MLA
Copy
Varfolomeev, S. D., et al. “Kinetics of Chemical Processes in the Human Brain. Trigger Effect and Self-Stabilization of N-Acetylaspartic Acid.” Doklady Physical Chemistry, vol. 484, no. 2, Feb. 2019, pp. 23-27. https://doi.org/10.1134/s0012501619020039.