volume 43 issue 4 pages 626-631

Selection of DNA aptamers specifically interacting with the fibrillar form of the yeast Sup35 protein

E R Surina 1
E. V. Morozkina 1
A.N. Marchenko 1
A A Antipin 2
O. V. Mitkevich 3
V V Kushnirov 3
M. D. Ter-Avanesyan 3
S.V. Benevolensky 1
Publication typeJournal Article
Publication date2009-08-25
scimago Q3
wos Q4
SJR0.331
CiteScore1.6
Impact factor1.2
ISSN00268933, 16083245, 21689547
Structural Biology
Biophysics
Abstract
Single-stranded DNA aptamers interacting with fibrils of Saccharomyces cerevisiae Sup35p were obtained by the SELEX procedure. The specificity of interactions with Sup35p was investigated for 10 out of 40 selected aptamers. Nine aptamers were found to bind to the fibrillar but not to the monomeric form of Sup35p. The dissociation constant of the aptamer-fibril complex ranged from 0.1 to 1.0 μM for different aptamers. The aptamers can be used to study the prion transformation of Sup35p.
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Surina E. R. et al. Selection of DNA aptamers specifically interacting with the fibrillar form of the yeast Sup35 protein // Molecular Biology. 2009. Vol. 43. No. 4. pp. 626-631.
GOST all authors (up to 50) Copy
Surina E. R., Morozkina E. V., Marchenko A., Antipin A. A., Mitkevich O. V., Kushnirov V. V., Ter-Avanesyan M. D., Benevolensky S. Selection of DNA aptamers specifically interacting with the fibrillar form of the yeast Sup35 protein // Molecular Biology. 2009. Vol. 43. No. 4. pp. 626-631.
RIS |
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RIS Copy
TY - JOUR
DO - 10.1134/s0026893309040153
UR - https://doi.org/10.1134/s0026893309040153
TI - Selection of DNA aptamers specifically interacting with the fibrillar form of the yeast Sup35 protein
T2 - Molecular Biology
AU - Surina, E R
AU - Morozkina, E. V.
AU - Marchenko, A.N.
AU - Antipin, A A
AU - Mitkevich, O. V.
AU - Kushnirov, V V
AU - Ter-Avanesyan, M. D.
AU - Benevolensky, S.V.
PY - 2009
DA - 2009/08/25
PB - Pleiades Publishing
SP - 626-631
IS - 4
VL - 43
SN - 0026-8933
SN - 1608-3245
SN - 2168-9547
ER -
BibTex |
Cite this
BibTex (up to 50 authors) Copy
@article{2009_Surina,
author = {E R Surina and E. V. Morozkina and A.N. Marchenko and A A Antipin and O. V. Mitkevich and V V Kushnirov and M. D. Ter-Avanesyan and S.V. Benevolensky},
title = {Selection of DNA aptamers specifically interacting with the fibrillar form of the yeast Sup35 protein},
journal = {Molecular Biology},
year = {2009},
volume = {43},
publisher = {Pleiades Publishing},
month = {aug},
url = {https://doi.org/10.1134/s0026893309040153},
number = {4},
pages = {626--631},
doi = {10.1134/s0026893309040153}
}
MLA
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MLA Copy
Surina, E. R., et al. “Selection of DNA aptamers specifically interacting with the fibrillar form of the yeast Sup35 protein.” Molecular Biology, vol. 43, no. 4, Aug. 2009, pp. 626-631. https://doi.org/10.1134/s0026893309040153.