Colloid Journal

, том 80 , издание 3 , страницы 312-319

The Effect of Molecular Architecture of Sulfobutyl Ether β-Cyclodextrin Nanoparticles on Physicochemical Properties of Complexes with Moxifloxacin

A A Skuredina ¹

I M Le Deygen ¹

E V Kudryashova ¹

Скрыть аффилиации авторов Показать аффилиации авторов: 1 аффилиация

Department of Chemistry, Moscow State University, Moscow, Russia |

Тип публикации: Journal Article

Дата публикации: 2018-05-01

Pleiades Publishing

Colloid Journal

scimago Q4

wos Q4

БС2

SJR: 0.220

CiteScore: 2.3

Impact factor: 1.1

ISSN: 1061933X, 16083067

DOI: 10.1134/S1061933X18030134

Скопировать DOI

Physical and Theoretical Chemistry

Colloid and Surface Chemistry

Surfaces and Interfaces

Краткое описание

A method has been developed for nanoparticles synthesis based on oligomers of sulfobutyl ether β-cyclodextrin (SBE-β-CD) and their structure has been studied by FTIR spectroscopy. The physicochemical properties of “guest−host” inclusion complexes formed by SBE-β-CD and its oligomers with moxifloxacin have been investigated. It has been shown that, as compared with SBE-β-CD, the synthesized oligomers have an increased affinity for moxifloxacin: the dissociation constants for the complexes of monomeric and oligomeric SBE-β-CD are (1.0 ± 0.3) × 10−4 and nearly 5 × 10−6 M, respectively. The binding efficiency increases due to the multy-point interaction of a moxifloxacin molecule with functional groups of the oligomeric carrier. SBE-β-CD oligomers are promising carriers for drugs, in particular, fluoroquinolone-based antibacterial agents, and may be used for the development of new compositions with improved solubility, bioavailability, and prolonged drug release.

Найдено

6 цитирований

Ле-Дейген Ирина

🥼 🤝

к.х.н.

67 публикаций, 2 728 цитирований, 8 рецензий

Индекс Хирша: 18

Московский государственный университет имени М.В. Ломоносова

Области научных интересов

Полимеры для доставки лекарств

Системы доставки лекарственных веществ

Ферменты

Хитозан

Экзосомы

Топ-30

Журналы

	1 2
Colloid Journal	Colloid Journal, 2, 12.5% Colloid Journal 2 публикации, 12.5%
Moscow University Chemistry Bulletin	Moscow University Chemistry Bulletin, 2, 12.5% Moscow University Chemistry Bulletin 2 публикации, 12.5%
Pharmaceutics	Pharmaceutics, 2, 12.5% Pharmaceutics 2 публикации, 12.5%
Biotekhnologiya	Biotekhnologiya, 2, 12.5% Biotekhnologiya 2 публикации, 12.5%
Reactive and Functional Polymers	Reactive and Functional Polymers, 1, 6.25% Reactive and Functional Polymers 1 публикация, 6.25%
Polymers	Polymers, 1, 6.25% Polymers 1 публикация, 6.25%
Nanomaterials	Nanomaterials, 1, 6.25% Nanomaterials 1 публикация, 6.25%
Molecules	Molecules, 1, 6.25% Molecules 1 публикация, 6.25%
Colloids and Surfaces A: Physicochemical and Engineering Aspects	Colloids and Surfaces A: Physicochemical and Engineering Aspects, 1, 6.25% Colloids and Surfaces A: Physicochemical and Engineering Aspects 1 публикация, 6.25%
Journal of Molecular Structure	Journal of Molecular Structure, 1, 6.25% Journal of Molecular Structure 1 публикация, 6.25%
Коллоидный журнал	Коллоидный журнал, 1, 6.25% Коллоидный журнал 1 публикация, 6.25%
Lomonosov chemistry journal	Lomonosov chemistry journal, 1, 6.25% Lomonosov chemistry journal 1 публикация, 6.25%
	1 2

Издатели

	1 2 3 4 5
MDPI	MDPI, 5, 31.25% MDPI 5 публикаций, 31.25%
Pleiades Publishing	Pleiades Publishing, 4, 25% Pleiades Publishing 4 публикации, 25%
Elsevier	Elsevier, 3, 18.75% Elsevier 3 публикации, 18.75%
State Research Institute for Genetics and Selection of Industrial Microorganisms	State Research Institute for Genetics and Selection of Industrial Microorganisms, 2, 12.5% State Research Institute for Genetics and Selection of Industrial Microorganisms 2 публикации, 12.5%
The Russian Academy of Sciences	The Russian Academy of Sciences, 1, 6.25% The Russian Academy of Sciences 1 публикация, 6.25%
Moscow University Press	Moscow University Press, 1, 6.25% Moscow University Press 1 публикация, 6.25%
	1 2 3 4 5

Мы не учитываем публикации, у которых нет DOI.
Статистика публикаций обновляется еженедельно.

Вы ученый?

Создайте профиль, чтобы получать персональные рекомендации коллег, конференций и новых статей.

Войти с ORCID

Метрики

Цитировать

ГОСТ |

Цитировать

ГОСТ Скопировать

Skuredina A. A., Le Deygen I. M., Kudryashova E. V. The Effect of Molecular Architecture of Sulfobutyl Ether β-Cyclodextrin Nanoparticles on Physicochemical Properties of Complexes with Moxifloxacin // Colloid Journal. 2018. Vol. 80. No. 3. pp. 312-319.

ГОСТ со всеми авторами (до 50) Скопировать

RIS |

Цитировать

RIS Скопировать

TY - JOUR

DO - 10.1134/S1061933X18030134

UR - https://doi.org/10.1134/S1061933X18030134

TI - The Effect of Molecular Architecture of Sulfobutyl Ether β-Cyclodextrin Nanoparticles on Physicochemical Properties of Complexes with Moxifloxacin

T2 - Colloid Journal

AU - Skuredina, A A

AU - Le Deygen, I M

AU - Kudryashova, E V

PY - 2018

DA - 2018/05/01

PB - Pleiades Publishing

SP - 312-319

IS - 3

VL - 80

SN - 1061-933X

SN - 1608-3067

ER -

BibTex |

Цитировать

BibTex (до 50 авторов) Скопировать

@article{2018_Skuredina,

author = {A A Skuredina and I M Le Deygen and E V Kudryashova},

title = {The Effect of Molecular Architecture of Sulfobutyl Ether β-Cyclodextrin Nanoparticles on Physicochemical Properties of Complexes with Moxifloxacin},

journal = {Colloid Journal},

year = {2018},

volume = {80},

publisher = {Pleiades Publishing},

month = {may},

url = {https://doi.org/10.1134/S1061933X18030134},

number = {3},

pages = {312--319},

doi = {10.1134/S1061933X18030134}

}

MLA

Цитировать

MLA Скопировать

Skuredina, A. A., et al. “The Effect of Molecular Architecture of Sulfobutyl Ether β-Cyclodextrin Nanoparticles on Physicochemical Properties of Complexes with Moxifloxacin.” Colloid Journal, vol. 80, no. 3, May. 2018, pp. 312-319. https://doi.org/10.1134/S1061933X18030134.

Издатель

Pleiades Publishing

Журнал

Colloid Journal

scimago Q4

wos Q4

БС2

SJR

0.220

CiteScore

2.3

Impact factor

1.1

ISSN

1061933X (Print)

16083067 (Electronic)

Профили