Journal of Analytical Chemistry, volume 70, issue 4, pages 495-501

Development of methods of the gas chromatographic determination of phenylcarboxylic acids in blood serum and their adaptation to clinical laboratory conditions

Publication typeJournal Article
Publication date2015-03-21
Quartile SCImago
Q4
Quartile WOS
Q4
Impact factor1.1
ISSN10619348, 16083199
Analytical Chemistry
Abstract
A method has been developed for the determination of phenylcarboxylic acids (benzoic, p-hydroxyphenyllactic, p-hydroxyphenylacetic, phenyllactic, 3-phenylpropanoic, and phenylacetic) in blood serum by gas chromatography with a flame-ionization detector (FID). The quantitative characteristics of analysis obtained with the FID and mass spectrometric detectors are in the same range and exhibit common trends for different groups of samples. It has been shown that the reproducibility of the results increases with the addition of a stage of salting out to the sample preparation procedure. The accuracy of the results is estimated using the added-found method. A possibility of the application of widely used FID to the quantitative determination of phenylcarboxylic acids in blood serum has been demonstrated for routine clinical practice.

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Moroz V. V. et al. Development of methods of the gas chromatographic determination of phenylcarboxylic acids in blood serum and their adaptation to clinical laboratory conditions // Journal of Analytical Chemistry. 2015. Vol. 70. No. 4. pp. 495-501.
GOST all authors (up to 50) Copy
Moroz V. V., Beloborodova N. V., Bedova A. Yu., Revelskii A. I., Getsina M. L., Osipov A. A., Sarshor Yu. N., Buchinskaya A. A., Olenin A. Yu. Development of methods of the gas chromatographic determination of phenylcarboxylic acids in blood serum and their adaptation to clinical laboratory conditions // Journal of Analytical Chemistry. 2015. Vol. 70. No. 4. pp. 495-501.
RIS |
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RIS Copy
TY - JOUR
DO - 10.1134/s1061934815040103
UR - https://doi.org/10.1134/s1061934815040103
TI - Development of methods of the gas chromatographic determination of phenylcarboxylic acids in blood serum and their adaptation to clinical laboratory conditions
T2 - Journal of Analytical Chemistry
AU - Moroz, V V
AU - Beloborodova, N V
AU - Bedova, A Yu
AU - Revelskii, A I
AU - Getsina, M L
AU - Osipov, A. A.
AU - Sarshor, Yu N
AU - Buchinskaya, A A
AU - Olenin, A Yu
PY - 2015
DA - 2015/03/21 00:00:00
PB - Pleiades Publishing
SP - 495-501
IS - 4
VL - 70
SN - 1061-9348
SN - 1608-3199
ER -
BibTex |
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BibTex Copy
@article{2015_Moroz,
author = {V V Moroz and N V Beloborodova and A Yu Bedova and A I Revelskii and M L Getsina and A. A. Osipov and Yu N Sarshor and A A Buchinskaya and A Yu Olenin},
title = {Development of methods of the gas chromatographic determination of phenylcarboxylic acids in blood serum and their adaptation to clinical laboratory conditions},
journal = {Journal of Analytical Chemistry},
year = {2015},
volume = {70},
publisher = {Pleiades Publishing},
month = {mar},
url = {https://doi.org/10.1134/s1061934815040103},
number = {4},
pages = {495--501},
doi = {10.1134/s1061934815040103}
}
MLA
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MLA Copy
Moroz, V. V., et al. “Development of methods of the gas chromatographic determination of phenylcarboxylic acids in blood serum and their adaptation to clinical laboratory conditions.” Journal of Analytical Chemistry, vol. 70, no. 4, Mar. 2015, pp. 495-501. https://doi.org/10.1134/s1061934815040103.
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