Pleiades Publishing
Russian Journal of Bioorganic Chemistry
,  volume 41 ,  issue 5 ,  pages 548-553

Enantioselective synthesis of (R)- and (S)-3-methylspermidines

Publication type: Journal Article
Publication date: 2015-09-22
Pleiades Publishing
scimago Q4
wos Q3
SJR: 0.267
CiteScore: 1.9
Impact factor: 1.7
ISSN: 10681620, 1608330X, 15739163
Organic Chemistry
Biochemistry
Abstract
Earlier unknown enantiomerically pure (R)- and (S)-1,8-diamino-3-methyl-4-azaoctane’s (3-MeSpd’s) were synthesized within 11 steps with high overall yields and optical purity starting from commercially available R- and S-isomers of N-Boc-2-aminopropanol-1. Application of R- and S-isomers of 3-MeSpd for the investigation of the stereospecificity of spermidine transporter and peculiarities of deoxyhypusine synthase reaction are discussed.
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GOST |
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GOST Copy
Khomutov M. A. et al. Enantioselective synthesis of (R)- and (S)-3-methylspermidines // Russian Journal of Bioorganic Chemistry. 2015. Vol. 41. No. 5. pp. 548-553.
GOST all authors (up to 50) Copy
Khomutov M. A., Keinänen T., Hyvönen M., Weisell J., Vepsäläinen J., Alhonen L., Kochetkov S. N., Khomutov A. R. Enantioselective synthesis of (R)- and (S)-3-methylspermidines // Russian Journal of Bioorganic Chemistry. 2015. Vol. 41. No. 5. pp. 548-553.
RIS |
Cite this
RIS Copy
TY - JOUR
DO - 10.1134/S1068162015050064
UR - https://doi.org/10.1134/S1068162015050064
TI - Enantioselective synthesis of (R)- and (S)-3-methylspermidines
T2 - Russian Journal of Bioorganic Chemistry
AU - Khomutov, M A
AU - Keinänen, T.A.
AU - Hyvönen, M.T.
AU - Weisell, J
AU - Vepsäläinen, J.
AU - Alhonen, L
AU - Kochetkov, S. N.
AU - Khomutov, A R
PY - 2015
DA - 2015/09/22
PB - Pleiades Publishing
SP - 548-553
IS - 5
VL - 41
PMID - 26762100
SN - 1068-1620
SN - 1608-330X
SN - 1573-9163
ER -
BibTex |
Cite this
BibTex (up to 50 authors) Copy
@article{2015_Khomutov,
author = {M A Khomutov and T.A. Keinänen and M.T. Hyvönen and J Weisell and J. Vepsäläinen and L Alhonen and S. N. Kochetkov and A R Khomutov},
title = {Enantioselective synthesis of (R)- and (S)-3-methylspermidines},
journal = {Russian Journal of Bioorganic Chemistry},
year = {2015},
volume = {41},
publisher = {Pleiades Publishing},
month = {sep},
url = {https://doi.org/10.1134/S1068162015050064},
number = {5},
pages = {548--553},
doi = {10.1134/S1068162015050064}
}
MLA
Cite this
MLA Copy
Khomutov, M. A., et al. “Enantioselective synthesis of (R)- and (S)-3-methylspermidines.” Russian Journal of Bioorganic Chemistry, vol. 41, no. 5, Sep. 2015, pp. 548-553. https://doi.org/10.1134/S1068162015050064.