Optimization of the Technology for the Preparation of Cationic Liposomes for the Delivery of Nucleic Acids
A S Luneva
1
,
P A Puchkov
1
,
E V Shmendel
1
,
M. A. Zenkova
2
,
A Yu Kuzevanova
3
,
A.A. Alimov
3
,
A V Karpukhin
3
,
Publication type: Journal Article
Publication date: 2018-11-01
scimago Q4
wos Q3
SJR: 0.267
CiteScore: 1.9
Impact factor: 1.7
ISSN: 10681620, 1608330X, 15739163
Organic Chemistry
Biochemistry
Abstract
Cationic liposomes based on the cationic lipid 1,26-bis(cholest-5-en-3β-yloxycarbonylamino)- 7,11,16-2-tetraazahexacosane tetrahydrochloride (2X3) and the helper lipid 1,2-dioleoyl-sn-glycero-3-phosphatidylethanolamine (DOPE) have been prepared by two methods, namely ultrasonication and the extrusion of a lipid dispersion. The effect of the preparation method and the type of the water phase on the physicochemical characteristics of cationic liposomes and their biological activity has been studied. The optimization of the preparation of cationic liposomes made it possible to determine the technological parameters providing the reproducibility of physicochemical characteristics of liposomes from batch to batch.
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Total citations:
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Citations from 2024:
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(53%)
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GOST
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Luneva A. S. et al. Optimization of the Technology for the Preparation of Cationic Liposomes for the Delivery of Nucleic Acids // Russian Journal of Bioorganic Chemistry. 2018. Vol. 44. No. 6. pp. 724-731.
GOST all authors (up to 50)
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Luneva A. S., Puchkov P. A., Shmendel E. V., Zenkova M. A., Kuzevanova A. Yu., Alimov A., Karpukhin A. V., Maslov M. A. Optimization of the Technology for the Preparation of Cationic Liposomes for the Delivery of Nucleic Acids // Russian Journal of Bioorganic Chemistry. 2018. Vol. 44. No. 6. pp. 724-731.
Cite this
RIS
Copy
TY - JOUR
DO - 10.1134/S1068162019010084
UR - http://link.springer.com/10.1134/S1068162019010084
TI - Optimization of the Technology for the Preparation of Cationic Liposomes for the Delivery of Nucleic Acids
T2 - Russian Journal of Bioorganic Chemistry
AU - Luneva, A S
AU - Puchkov, P A
AU - Shmendel, E V
AU - Zenkova, M. A.
AU - Kuzevanova, A Yu
AU - Alimov, A.A.
AU - Karpukhin, A V
AU - Maslov, M A
PY - 2018
DA - 2018/11/01
PB - Pleiades Publishing
SP - 724-731
IS - 6
VL - 44
SN - 1068-1620
SN - 1608-330X
SN - 1573-9163
ER -
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BibTex (up to 50 authors)
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@article{2018_Luneva,
author = {A S Luneva and P A Puchkov and E V Shmendel and M. A. Zenkova and A Yu Kuzevanova and A.A. Alimov and A V Karpukhin and M A Maslov},
title = {Optimization of the Technology for the Preparation of Cationic Liposomes for the Delivery of Nucleic Acids},
journal = {Russian Journal of Bioorganic Chemistry},
year = {2018},
volume = {44},
publisher = {Pleiades Publishing},
month = {nov},
url = {http://link.springer.com/10.1134/S1068162019010084},
number = {6},
pages = {724--731},
doi = {10.1134/S1068162019010084}
}
Cite this
MLA
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Luneva, A. S., et al. “Optimization of the Technology for the Preparation of Cationic Liposomes for the Delivery of Nucleic Acids.” Russian Journal of Bioorganic Chemistry, vol. 44, no. 6, Nov. 2018, pp. 724-731. http://link.springer.com/10.1134/S1068162019010084.
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