Pleiades Publishing
Russian Journal of Bioorganic Chemistry
,  volume 46 ,  issue 6 ,  pages 1250-1260

Uncharged Gemini-Amphiphiles as Components of Cationic Liposomes for Delivery of Nucleic Acids

Publication type: Journal Article
Publication date: 2020-11-01
Pleiades Publishing
scimago Q4
wos Q3
SJR: 0.267
CiteScore: 1.9
Impact factor: 1.7
ISSN: 10681620, 1608330X, 15739163
Organic Chemistry
Biochemistry
Abstract
New uncharged gemini-amphiphiles have been synthesized. A series of cationic liposomes based on the polycationic amphiphile 1,26-bis(cholest-5-en-3β-yloxycarbonylamino)-7,11,16,20-tetraazahexacosan tetrahydrochloride (2X3), 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine (DOPE) and uncharged gemini-amphiphiles that contain short hydrophobic and long hydrophilic spacers have been prepared. The physicochemical characteristics, cytotoxicity, and transfection activity of cationic liposomes have been studied. Cationic liposomes that include 10% (mol) of a uncharged gemini-amphiphile with the oligooxymethylene spacer have formed small complexes with plasmid DNA and efficiently delivered it into eukaryotic cells.
Found 
Found 

Top-30

Journals

1
2
Russian Journal of Bioorganic Chemistry
Russian Journal of Bioorganic Chemistry, 2, 50%
Russian Journal of Bioorganic Chemistry
2 publications, 50%
Pharmaceutics
Pharmaceutics, 1, 25%
Pharmaceutics
1 publication, 25%
Molecules
Molecules, 1, 25%
Molecules
1 publication, 25%
1
2

Publishers

1
2
Pleiades Publishing
Pleiades Publishing, 2, 50%
Pleiades Publishing
2 publications, 50%
MDPI
MDPI, 2, 50%
MDPI
2 publications, 50%
1
2
  • We do not take into account publications without a DOI.
  • Statistics recalculated weekly.

Are you a researcher?

Create a profile to get free access to personal recommendations for colleagues and new articles.
Metrics
4
Share
Cite this
GOST |
Cite this
GOST Copy
Shmendel E. V. et al. Uncharged Gemini-Amphiphiles as Components of Cationic Liposomes for Delivery of Nucleic Acids // Russian Journal of Bioorganic Chemistry. 2020. Vol. 46. No. 6. pp. 1250-1260.
GOST all authors (up to 50) Copy
Shmendel E. V., Bakhareva S. A., Makarova D. M., Chernikov I. V., Morozova N. G., Chernolovskaya E. L., Zenkova M. A., Maslov M. A. Uncharged Gemini-Amphiphiles as Components of Cationic Liposomes for Delivery of Nucleic Acids // Russian Journal of Bioorganic Chemistry. 2020. Vol. 46. No. 6. pp. 1250-1260.
RIS |
Cite this
RIS Copy
TY - JOUR
DO - 10.1134/S106816202006031X
UR - http://link.springer.com/10.1134/S106816202006031X
TI - Uncharged Gemini-Amphiphiles as Components of Cationic Liposomes for Delivery of Nucleic Acids
T2 - Russian Journal of Bioorganic Chemistry
AU - Shmendel, E V
AU - Bakhareva, S A
AU - Makarova, D M
AU - Chernikov, I V
AU - Morozova, N G
AU - Chernolovskaya, E. L.
AU - Zenkova, M. A.
AU - Maslov, M A
PY - 2020
DA - 2020/11/01
PB - Pleiades Publishing
SP - 1250-1260
IS - 6
VL - 46
SN - 1068-1620
SN - 1608-330X
SN - 1573-9163
ER -
BibTex |
Cite this
BibTex (up to 50 authors) Copy
@article{2020_Shmendel,
author = {E V Shmendel and S A Bakhareva and D M Makarova and I V Chernikov and N G Morozova and E. L. Chernolovskaya and M. A. Zenkova and M A Maslov},
title = {Uncharged Gemini-Amphiphiles as Components of Cationic Liposomes for Delivery of Nucleic Acids},
journal = {Russian Journal of Bioorganic Chemistry},
year = {2020},
volume = {46},
publisher = {Pleiades Publishing},
month = {nov},
url = {http://link.springer.com/10.1134/S106816202006031X},
number = {6},
pages = {1250--1260},
doi = {10.1134/S106816202006031X}
}
MLA
Cite this
MLA Copy
Shmendel, E. V., et al. “Uncharged Gemini-Amphiphiles as Components of Cationic Liposomes for Delivery of Nucleic Acids.” Russian Journal of Bioorganic Chemistry, vol. 46, no. 6, Nov. 2020, pp. 1250-1260. http://link.springer.com/10.1134/S106816202006031X.