Isatin Derivatives Containing Sterically Hindered Phenolic Fragment and Water-Soluble Acyl Hydrazones on Their Basis: Synthesis and Antimicrobial Activity
A. V. BOGDANOV
1
,
I F Zaripova
2
,
A D Voloshina
1
,
A S Strobykina
1
,
N V Kulik
1
,
S V Bukharov
2
,
Publication type: Journal Article
Publication date: 2018-01-01
scimago Q4
wos Q4
SJR: 0.179
CiteScore: 1.4
Impact factor: 0.8
ISSN: 10703632, 16083350
General Chemistry
Abstract
Condensation reactions of isatin derivatives with 3,5-di(tert-butyl)-4-hydroxybenzyl acetate and the Girard’s reagent T has afforded a series of novel water-soluble isatin-3-acyl hydrazones containing a sterically hindered phenolic fragment in position 1 of the heterocycle; antimicrobial activity of the products has been estimated. It has been shown that the isatin derivatives with bromine or methoxy substituent in the benzo fragment as well as the acyl hydrazones containing 5-methyl or 5-ethyl group are the most active against Staphylococcus aureus and Bacillus cereus.
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BOGDANOV A. V. et al. Isatin Derivatives Containing Sterically Hindered Phenolic Fragment and Water-Soluble Acyl Hydrazones on Their Basis: Synthesis and Antimicrobial Activity // Russian Journal of General Chemistry. 2018. Vol. 88. No. 1. pp. 57-67.
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BOGDANOV A. V., Zaripova I. F., Voloshina A. D., Strobykina A. S., Kulik N. V., Bukharov S. V., Mironov V. F. Isatin Derivatives Containing Sterically Hindered Phenolic Fragment and Water-Soluble Acyl Hydrazones on Their Basis: Synthesis and Antimicrobial Activity // Russian Journal of General Chemistry. 2018. Vol. 88. No. 1. pp. 57-67.
Cite this
RIS
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TY - JOUR
DO - 10.1134/S1070363218010097
UR - https://doi.org/10.1134/S1070363218010097
TI - Isatin Derivatives Containing Sterically Hindered Phenolic Fragment and Water-Soluble Acyl Hydrazones on Their Basis: Synthesis and Antimicrobial Activity
T2 - Russian Journal of General Chemistry
AU - BOGDANOV, A. V.
AU - Zaripova, I F
AU - Voloshina, A D
AU - Strobykina, A S
AU - Kulik, N V
AU - Bukharov, S V
AU - Mironov, V F
PY - 2018
DA - 2018/01/01
PB - Pleiades Publishing
SP - 57-67
IS - 1
VL - 88
SN - 1070-3632
SN - 1608-3350
ER -
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BibTex (up to 50 authors)
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@article{2018_BOGDANOV,
author = {A. V. BOGDANOV and I F Zaripova and A D Voloshina and A S Strobykina and N V Kulik and S V Bukharov and V F Mironov},
title = {Isatin Derivatives Containing Sterically Hindered Phenolic Fragment and Water-Soluble Acyl Hydrazones on Their Basis: Synthesis and Antimicrobial Activity},
journal = {Russian Journal of General Chemistry},
year = {2018},
volume = {88},
publisher = {Pleiades Publishing},
month = {jan},
url = {https://doi.org/10.1134/S1070363218010097},
number = {1},
pages = {57--67},
doi = {10.1134/S1070363218010097}
}
Cite this
MLA
Copy
BOGDANOV, A. V., et al. “Isatin Derivatives Containing Sterically Hindered Phenolic Fragment and Water-Soluble Acyl Hydrazones on Their Basis: Synthesis and Antimicrobial Activity.” Russian Journal of General Chemistry, vol. 88, no. 1, Jan. 2018, pp. 57-67. https://doi.org/10.1134/S1070363218010097.