Pleiades Publishing
Russian Journal of General Chemistry
,  volume 92 ,  issue 2 ,  pages 185-197

7-Aryl-3-(hydroxymethyl)-5-oxo-1,2,3,5-tetrahydro[1,2,4]triazolo[1,5-a]pyridine-6,8-dicarbonitriles: Synthesis and Predicted Biological Activity

Publication type: Journal Article
Publication date: 2022-02-01
Pleiades Publishing
scimago Q4
wos Q4
SJR: 0.179
CiteScore: 1.4
Impact factor: 0.8
ISSN: 10703632, 16083350
General Chemistry
Abstract
Aminomethylation of 1,6-diamino-4-aryl-2-oxo-1,2-dihydropyridine-3,5-dicarbonitriles under the action of excess of formaldehyde in ethanol has led to the formation of 7-aryl-3-(hydroxymethyl)-5-oxo-1,2,3,5-tetrahydro[1,2,4]triazolo[1,5-a]pyridine-6,8-dicarbonitriles. Bioavailability parameters of the obtained compounds have been predicted in silico and the possible protein targets have been predicted via the protein-ligand docking.
Found 
Found 
2 citations
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GOST Copy
Dolganov A. A. et al. 7-Aryl-3-(hydroxymethyl)-5-oxo-1,2,3,5-tetrahydro[1,2,4]triazolo[1,5-a]pyridine-6,8-dicarbonitriles: Synthesis and Predicted Biological Activity // Russian Journal of General Chemistry. 2022. Vol. 92. No. 2. pp. 185-197.
GOST all authors (up to 50) Copy
Dolganov A. A., Levchenko A. G., Dahno P. G., Guz D. D., Chikava A. R., Dotsenko V. V., Aksenov N. A., Aksenova I. V. 7-Aryl-3-(hydroxymethyl)-5-oxo-1,2,3,5-tetrahydro[1,2,4]triazolo[1,5-a]pyridine-6,8-dicarbonitriles: Synthesis and Predicted Biological Activity // Russian Journal of General Chemistry. 2022. Vol. 92. No. 2. pp. 185-197.
RIS |
Cite this
RIS Copy
TY - JOUR
DO - 10.1134/s1070363222020074
UR - https://doi.org/10.1134/s1070363222020074
TI - 7-Aryl-3-(hydroxymethyl)-5-oxo-1,2,3,5-tetrahydro[1,2,4]triazolo[1,5-a]pyridine-6,8-dicarbonitriles: Synthesis and Predicted Biological Activity
T2 - Russian Journal of General Chemistry
AU - Dolganov, A A
AU - Levchenko, A G
AU - Dahno, P G
AU - Guz, D D
AU - Chikava, A R
AU - Dotsenko, Viktor V
AU - Aksenov, Nicolai A.
AU - Aksenova, Inna V.
PY - 2022
DA - 2022/02/01
PB - Pleiades Publishing
SP - 185-197
IS - 2
VL - 92
SN - 1070-3632
SN - 1608-3350
ER -
BibTex |
Cite this
BibTex (up to 50 authors) Copy
@article{2022_Dolganov,
author = {A A Dolganov and A G Levchenko and P G Dahno and D D Guz and A R Chikava and Viktor V Dotsenko and Nicolai A. Aksenov and Inna V. Aksenova},
title = {7-Aryl-3-(hydroxymethyl)-5-oxo-1,2,3,5-tetrahydro[1,2,4]triazolo[1,5-a]pyridine-6,8-dicarbonitriles: Synthesis and Predicted Biological Activity},
journal = {Russian Journal of General Chemistry},
year = {2022},
volume = {92},
publisher = {Pleiades Publishing},
month = {feb},
url = {https://doi.org/10.1134/s1070363222020074},
number = {2},
pages = {185--197},
doi = {10.1134/s1070363222020074}
}
MLA
Cite this
MLA Copy
Dolganov, A. A., et al. “7-Aryl-3-(hydroxymethyl)-5-oxo-1,2,3,5-tetrahydro[1,2,4]triazolo[1,5-a]pyridine-6,8-dicarbonitriles: Synthesis and Predicted Biological Activity.” Russian Journal of General Chemistry, vol. 92, no. 2, Feb. 2022, pp. 185-197. https://doi.org/10.1134/s1070363222020074.