Synthesis and biological activity of oxindolylidene derivatives of imidazo[4,5-e]thiazolo[3,2-b]-1,2,4-triazin-7-ones and imidazo[4,5-e]thiazolo[2,3-N]-1,2,4-triazin-8-ones
Publication type: Journal Article
Publication date: 2017-05-01
scimago Q4
wos Q4
SJR: 0.190
CiteScore: 1.3
Impact factor: 0.9
ISSN: 10704280, 16083393
Organic Chemistry
Abstract
Reactions of 1,3-dialkyl-2-thioxo-1,2,3,3a,9,9a-hexahydroimidazo[4,5-e]thiazolo[3,2-b]-1,2,4-triazin-7(6H)-ones with isatin and its derivatives under base catalysis conditions lead to the corresponding 1,3-dialkyl-6(7)-(2-oxoindolin-3-ylidene)derivatives of 2-thioxo-1,2,3,3a,9,9a-hexahydroimidazo[4,5-e]thiazolo[3,2-b]-1,2,4-triazin-7(6H)-one or 2-thioxo-1,2,3,3a,4,9a-hexahydroimidazo[4,5-e]thiazolo[2,3-c]-1,2,4-triazin-8(7H)-one resulting from the aldol-crotonic condensation and skeletal amidine rearrangement of the thiazolotriazine fragment, depending on the amount of added alkali.
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Izmestev A. N. et al. Synthesis and biological activity of oxindolylidene derivatives of imidazo[4,5-e]thiazolo[3,2-b]-1,2,4-triazin-7-ones and imidazo[4,5-e]thiazolo[2,3-N]-1,2,4-triazin-8-ones // Russian Journal of Organic Chemistry. 2017. Vol. 53. No. 5. pp. 753-763.
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Izmestev A. N., Gazieva G. A., Kulikov A., Anikina L. V., Kolotyrkina N. G., Kravchenko A. N. Synthesis and biological activity of oxindolylidene derivatives of imidazo[4,5-e]thiazolo[3,2-b]-1,2,4-triazin-7-ones and imidazo[4,5-e]thiazolo[2,3-N]-1,2,4-triazin-8-ones // Russian Journal of Organic Chemistry. 2017. Vol. 53. No. 5. pp. 753-763.
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TY - JOUR
DO - 10.1134/S1070428017050177
UR - http://link.springer.com/10.1134/S1070428017050177
TI - Synthesis and biological activity of oxindolylidene derivatives of imidazo[4,5-e]thiazolo[3,2-b]-1,2,4-triazin-7-ones and imidazo[4,5-e]thiazolo[2,3-N]-1,2,4-triazin-8-ones
T2 - Russian Journal of Organic Chemistry
AU - Izmestev, A N
AU - Gazieva, G A
AU - Kulikov, A.S
AU - Anikina, L V
AU - Kolotyrkina, N G
AU - Kravchenko, A N
PY - 2017
DA - 2017/05/01
PB - Pleiades Publishing
SP - 753-763
IS - 5
VL - 53
SN - 1070-4280
SN - 1608-3393
ER -
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@article{2017_Izmestev,
author = {A N Izmestev and G A Gazieva and A.S Kulikov and L V Anikina and N G Kolotyrkina and A N Kravchenko},
title = {Synthesis and biological activity of oxindolylidene derivatives of imidazo[4,5-e]thiazolo[3,2-b]-1,2,4-triazin-7-ones and imidazo[4,5-e]thiazolo[2,3-N]-1,2,4-triazin-8-ones},
journal = {Russian Journal of Organic Chemistry},
year = {2017},
volume = {53},
publisher = {Pleiades Publishing},
month = {may},
url = {http://link.springer.com/10.1134/S1070428017050177},
number = {5},
pages = {753--763},
doi = {10.1134/S1070428017050177}
}
Cite this
MLA
Copy
Izmestev, A. N., et al. “Synthesis and biological activity of oxindolylidene derivatives of imidazo[4,5-e]thiazolo[3,2-b]-1,2,4-triazin-7-ones and imidazo[4,5-e]thiazolo[2,3-N]-1,2,4-triazin-8-ones.” Russian Journal of Organic Chemistry, vol. 53, no. 5, May. 2017, pp. 753-763. http://link.springer.com/10.1134/S1070428017050177.