Open Access
Synthesis and Antimicrobial, Antiplatelet, and Anticoagulant Activities of New Isatin Deivatives Containing a Hetero-Fused Imidazole Fragment
Publication type: Journal Article
Publication date: 2022-03-01
scimago Q4
wos Q4
SJR: 0.190
CiteScore: 1.3
Impact factor: 0.9
ISSN: 10704280, 16083393
Organic Chemistry
Abstract
A series of isatin derivatives containing an adenine or theophylline fragment have been synthesized. The corresponding N′-[2-(trimethylammonio)acetyl] and N′-(2-pyridinioacetyl) hydrazones have been found to exhibit neither cytotoxicity nor hemotoxicity. Quaternary salts based on adenine derivatives of 5-methyl- and 5-ethylisatins showed the highest antiplatelet activity which exceeded the activity of acetylsalicylic acid by a factor of 1.5.
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Total citations:
8
Citations from 2024:
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(50%)
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GOST
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Bogdanov A. V. et al. Synthesis and Antimicrobial, Antiplatelet, and Anticoagulant Activities of New Isatin Deivatives Containing a Hetero-Fused Imidazole Fragment // Russian Journal of Organic Chemistry. 2022. Vol. 58. No. 3. pp. 327-334.
GOST all authors (up to 50)
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Bogdanov A. V., Sirazieva A. R., Voloshina A. D., Abzalilov T. A., Samorodov A. V., Mironov V. L. Synthesis and Antimicrobial, Antiplatelet, and Anticoagulant Activities of New Isatin Deivatives Containing a Hetero-Fused Imidazole Fragment // Russian Journal of Organic Chemistry. 2022. Vol. 58. No. 3. pp. 327-334.
Cite this
RIS
Copy
TY - JOUR
DO - 10.1134/S1070428022030101
UR - https://doi.org/10.1134/S1070428022030101
TI - Synthesis and Antimicrobial, Antiplatelet, and Anticoagulant Activities of New Isatin Deivatives Containing a Hetero-Fused Imidazole Fragment
T2 - Russian Journal of Organic Chemistry
AU - Bogdanov, Andrei V
AU - Sirazieva, A R
AU - Voloshina, A. D.
AU - Abzalilov, T A
AU - Samorodov, Aleksandr V
AU - Mironov, Valery L.
PY - 2022
DA - 2022/03/01
PB - Pleiades Publishing
SP - 327-334
IS - 3
VL - 58
SN - 1070-4280
SN - 1608-3393
ER -
Cite this
BibTex (up to 50 authors)
Copy
@article{2022_Bogdanov,
author = {Andrei V Bogdanov and A R Sirazieva and A. D. Voloshina and T A Abzalilov and Aleksandr V Samorodov and Valery L. Mironov},
title = {Synthesis and Antimicrobial, Antiplatelet, and Anticoagulant Activities of New Isatin Deivatives Containing a Hetero-Fused Imidazole Fragment},
journal = {Russian Journal of Organic Chemistry},
year = {2022},
volume = {58},
publisher = {Pleiades Publishing},
month = {mar},
url = {https://doi.org/10.1134/S1070428022030101},
number = {3},
pages = {327--334},
doi = {10.1134/S1070428022030101}
}
Cite this
MLA
Copy
Bogdanov, Andrei V., et al. “Synthesis and Antimicrobial, Antiplatelet, and Anticoagulant Activities of New Isatin Deivatives Containing a Hetero-Fused Imidazole Fragment.” Russian Journal of Organic Chemistry, vol. 58, no. 3, Mar. 2022, pp. 327-334. https://doi.org/10.1134/S1070428022030101.