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Russian Journal of Organic Chemistry

, том 58 , издание 3 , страницы 327-334

Synthesis and Antimicrobial, Antiplatelet, and Anticoagulant Activities of New Isatin Deivatives Containing a Hetero-Fused Imidazole Fragment

Andrei V Bogdanov ^{1, 2}

A R Sirazieva ¹

A. D. Voloshina ¹

T A Abzalilov ³

Aleksandr V Samorodov ³

Valery L. Mironov ¹

Скрыть аффилиации авторов Показать аффилиации авторов: 3 аффилиации

Arbuzov Institute of Organic and Physical Chemistry, Kazan Scientific Center, Russian Academy of Sciences, Kazan, Russia

Институт органической и физической химии им. А.Е. Арбузова КазНЦ РАН

Казанский научный центр РАН

Kazan (Volga region) Federal university, Kazan, Russia |

Bashkir State Medical University, Ministry of Health of the Russian Federation, Ufa, Russia |

Тип публикации: Journal Article

Дата публикации: 2022-03-01

Pleiades Publishing

Russian Journal of Organic Chemistry

scimago Q4

wos Q4

БС3

SJR: 0.190

CiteScore: 1.3

Impact factor: 0.9

ISSN: 10704280, 16083393

DOI: 10.1134/S1070428022030101

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Organic Chemistry

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A series of isatin derivatives containing an adenine or theophylline fragment have been synthesized. The corresponding N′-[2-(trimethylammonio)acetyl] and N′-(2-pyridinioacetyl) hydrazones have been found to exhibit neither cytotoxicity nor hemotoxicity. Quaternary salts based on adenine derivatives of 5-methyl- and 5-ethylisatins showed the highest antiplatelet activity which exceeded the activity of acetylsalicylic acid by a factor of 1.5.

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Russian Journal of General Chemistry	Russian Journal of General Chemistry, 2, 25% Russian Journal of General Chemistry 2 публикации, 25%
Drug development & registration	Drug development & registration, 1, 12.5% Drug development & registration 1 публикация, 12.5%
European Journal of Pharmaceutical Sciences	European Journal of Pharmaceutical Sciences, 1, 12.5% European Journal of Pharmaceutical Sciences 1 публикация, 12.5%
Russian Journal of Organic Chemistry	Russian Journal of Organic Chemistry, 1, 12.5% Russian Journal of Organic Chemistry 1 публикация, 12.5%
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Журнал органической химии	Журнал органической химии, 1, 12.5% Журнал органической химии 1 публикация, 12.5%
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Bogdanov A. V. et al. Synthesis and Antimicrobial, Antiplatelet, and Anticoagulant Activities of New Isatin Deivatives Containing a Hetero-Fused Imidazole Fragment // Russian Journal of Organic Chemistry. 2022. Vol. 58. No. 3. pp. 327-334.

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Bogdanov A. V., Sirazieva A. R., Voloshina A. D., Abzalilov T. A., Samorodov A. V., Mironov V. L. Synthesis and Antimicrobial, Antiplatelet, and Anticoagulant Activities of New Isatin Deivatives Containing a Hetero-Fused Imidazole Fragment // Russian Journal of Organic Chemistry. 2022. Vol. 58. No. 3. pp. 327-334.

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TY - JOUR

DO - 10.1134/S1070428022030101

UR - https://doi.org/10.1134/S1070428022030101

TI - Synthesis and Antimicrobial, Antiplatelet, and Anticoagulant Activities of New Isatin Deivatives Containing a Hetero-Fused Imidazole Fragment

T2 - Russian Journal of Organic Chemistry

AU - Bogdanov, Andrei V

AU - Sirazieva, A R

AU - Voloshina, A. D.

AU - Abzalilov, T A

AU - Samorodov, Aleksandr V

AU - Mironov, Valery L.

PY - 2022

DA - 2022/03/01

PB - Pleiades Publishing

SP - 327-334

IS - 3

VL - 58

SN - 1070-4280

SN - 1608-3393

ER -

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@article{2022_Bogdanov,

author = {Andrei V Bogdanov and A R Sirazieva and A. D. Voloshina and T A Abzalilov and Aleksandr V Samorodov and Valery L. Mironov},

title = {Synthesis and Antimicrobial, Antiplatelet, and Anticoagulant Activities of New Isatin Deivatives Containing a Hetero-Fused Imidazole Fragment},

journal = {Russian Journal of Organic Chemistry},

year = {2022},

volume = {58},

publisher = {Pleiades Publishing},

month = {mar},

url = {https://doi.org/10.1134/S1070428022030101},

number = {3},

pages = {327--334},

doi = {10.1134/S1070428022030101}

}

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Bogdanov, Andrei V., et al. “Synthesis and Antimicrobial, Antiplatelet, and Anticoagulant Activities of New Isatin Deivatives Containing a Hetero-Fused Imidazole Fragment.” Russian Journal of Organic Chemistry, vol. 58, no. 3, Mar. 2022, pp. 327-334. https://doi.org/10.1134/S1070428022030101.