Alkyl 2-arylhydrazinylidene-3-oxo-3-polyfluoroalkylpropionates as new effective and selective inhibitors of carboxylesterase
Тип публикации: Journal Article
Дата публикации: 2015-11-01
SCImago Q3
WOS Q4
БС3
SJR: 0.265
CiteScore: 1.3
Impact factor: 0.8
ISSN: 16076729, 16083091
PubMed ID:
26728730
General Chemistry
Biochemistry
General Medicine
Biophysics
Краткое описание
A series of alkyl 2-Arylhydrazinylidene-3-oxo-3-polyfluoroalkylpropionates was synthesized and their inhibitory activity with respect to porcine liver carboxylesterase (CaE, EC 3.1.1.1), human erythrocyte acetylcholinesterase (AChE, EC 3.1.1.7), and horse serum butyrylcholinesterase (BChE, EC 3.1.1.8) was studied. The molecular docking method was used to study the binding mode of the compounds in the active site of CaE. It was found that compounds containing the trifluoromethyl group in the third position of carbonyl chain are highly effective and selective inhibitors of CaE with nanomolar IC50 values, which agrees well with the results of molecular docking.
Найдено
Ничего не найдено, попробуйте изменить настройки фильтра.
Для доступа к списку цитирований публикации необходимо авторизоваться.
Для доступа к списку профилей, цитирующих публикацию, необходимо авторизоваться.
Топ-30
Журналы
|
1
2
3
4
5
6
|
|
|
Russian Chemical Bulletin
6 публикаций, 35.29%
|
|
|
Bioorganic and Medicinal Chemistry
2 публикации, 11.76%
|
|
|
Molecules
1 публикация, 5.88%
|
|
|
Chemistry of Heterocyclic Compounds
1 публикация, 5.88%
|
|
|
Journal of Fluorine Chemistry
1 публикация, 5.88%
|
|
|
Russian Chemical Reviews
1 публикация, 5.88%
|
|
|
Bioorganic Chemistry
1 публикация, 5.88%
|
|
|
Bioorganic and Medicinal Chemistry Letters
1 публикация, 5.88%
|
|
|
European Journal of Medicinal Chemistry
1 публикация, 5.88%
|
|
|
Biomedical Chemistry Research and Methods
1 публикация, 5.88%
|
|
|
AIP Conference Proceedings
1 публикация, 5.88%
|
|
|
1
2
3
4
5
6
|
Издатели
|
1
2
3
4
5
6
7
|
|
|
Springer Nature
7 публикаций, 41.18%
|
|
|
Elsevier
6 публикаций, 35.29%
|
|
|
MDPI
1 публикация, 5.88%
|
|
|
Autonomous Non-profit Organization Editorial Board of the journal Uspekhi Khimii
1 публикация, 5.88%
|
|
|
Institute of Biomedical Chemistry
1 публикация, 5.88%
|
|
|
AIP Publishing
1 публикация, 5.88%
|
|
|
1
2
3
4
5
6
7
|
- Мы не учитываем публикации, у которых нет DOI.
- Статистика публикаций обновляется еженедельно.
Вы ученый?
Создайте профиль, чтобы получать персональные рекомендации коллег, конференций и новых статей.
Войти с ORCID
Метрики
17
Всего цитирований:
17
Цитирований c 2025:
0
Цитировать
ГОСТ |
RIS |
BibTex |
MLA
Цитировать
ГОСТ
Скопировать
Boltneva N. P. et al. Alkyl 2-arylhydrazinylidene-3-oxo-3-polyfluoroalkylpropionates as new effective and selective inhibitors of carboxylesterase // Doklady Biochemistry and Biophysics. 2015. Vol. 465. No. 1. pp. 381-385.
ГОСТ со всеми авторами (до 50)
Скопировать
Boltneva N. P., Makhaeva G. F., Kovaleva N. V., Lushchekina S. V., Burgart Y. V., Shchegolkov E. V., Saloutin V. I., Chupakhin O. Alkyl 2-arylhydrazinylidene-3-oxo-3-polyfluoroalkylpropionates as new effective and selective inhibitors of carboxylesterase // Doklady Biochemistry and Biophysics. 2015. Vol. 465. No. 1. pp. 381-385.
Цитировать
RIS
Скопировать
TY - JOUR
DO - 10.1134/S1607672915060101
UR - https://doi.org/10.1134/S1607672915060101
TI - Alkyl 2-arylhydrazinylidene-3-oxo-3-polyfluoroalkylpropionates as new effective and selective inhibitors of carboxylesterase
T2 - Doklady Biochemistry and Biophysics
AU - Boltneva, N P
AU - Makhaeva, G. F.
AU - Kovaleva, N V
AU - Lushchekina, S V
AU - Burgart, Ya. V.
AU - Shchegolkov, E V
AU - Saloutin, V. I.
AU - Chupakhin, O.N.
PY - 2015
DA - 2015/11/01
PB - Pleiades Publishing
SP - 381-385
IS - 1
VL - 465
PMID - 26728730
SN - 1607-6729
SN - 1608-3091
ER -
Цитировать
BibTex (до 50 авторов)
Скопировать
@article{2015_Boltneva,
author = {N P Boltneva and G. F. Makhaeva and N V Kovaleva and S V Lushchekina and Ya. V. Burgart and E V Shchegolkov and V. I. Saloutin and O.N. Chupakhin},
title = {Alkyl 2-arylhydrazinylidene-3-oxo-3-polyfluoroalkylpropionates as new effective and selective inhibitors of carboxylesterase},
journal = {Doklady Biochemistry and Biophysics},
year = {2015},
volume = {465},
publisher = {Pleiades Publishing},
month = {nov},
url = {https://doi.org/10.1134/S1607672915060101},
number = {1},
pages = {381--385},
doi = {10.1134/S1607672915060101}
}
Цитировать
MLA
Скопировать
Boltneva, N. P., et al. “Alkyl 2-arylhydrazinylidene-3-oxo-3-polyfluoroalkylpropionates as new effective and selective inhibitors of carboxylesterase.” Doklady Biochemistry and Biophysics, vol. 465, no. 1, Nov. 2015, pp. 381-385. https://doi.org/10.1134/S1607672915060101.
Ошибка в публикации?