Pleiades Publishing
Doklady Biochemistry and Biophysics
,  volume 467 ,  issue 1 ,  pages 128-131

The oxidative modification of cellular fibrin-stabilizing factor

M. A. Rosenfeld 1
, 
A N Shchegolikhin 1
, 
V B Leonova 1
, 
E A Kostanova 1
, 
M I Biryukova 1
, 
A.V. Bychkova 1
, 
M L Konstantinova 1
, 
A D Vasilyeva 1
1
 
Publication type: Journal Article
Publication date: 2016-03-01
Pleiades Publishing
scimago Q3
wos Q4
SJR: 0.223
CiteScore: 1.5
Impact factor: 0.7
ISSN: 16076729, 16083091
General Chemistry
Biochemistry
General Medicine
Biophysics
Abstract
For the first time, the induced oxidative modification of cellular fibrin-stabilizing factor (cFXIII) has been studied. According to the electrophoresis analysis, the conversion of oxidized cFXIII into FXIIIa resulted in producing the enzyme that significantly lost the initial enzymatic activity. At the same time, FXIIIa subjected to induced oxidation was completely devoid of enzymatic activity. The results of FTIR spectroscopy showed that the oxidation of cFXIII or FXIIIa was accompanied by profound changes both in chemical and spatial structures of the protein. The results of this study are in good agreement with our earlier assumption regarding the antioxidant role of the regulatory subunits B of plasma fibrin-stabilizing factor.
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GOST Copy
Rosenfeld M. A. et al. The oxidative modification of cellular fibrin-stabilizing factor // Doklady Biochemistry and Biophysics. 2016. Vol. 467. No. 1. pp. 128-131.
GOST all authors (up to 50) Copy
Rosenfeld M. A., Shchegolikhin A. N., Leonova V. B., Kostanova E. A., Biryukova M. I., Bychkova A., Konstantinova M. L., Vasilyeva A. D. The oxidative modification of cellular fibrin-stabilizing factor // Doklady Biochemistry and Biophysics. 2016. Vol. 467. No. 1. pp. 128-131.
RIS |
Cite this
RIS Copy
TY - JOUR
DO - 10.1134/S1607672916020149
UR - https://doi.org/10.1134/S1607672916020149
TI - The oxidative modification of cellular fibrin-stabilizing factor
T2 - Doklady Biochemistry and Biophysics
AU - Rosenfeld, M. A.
AU - Shchegolikhin, A N
AU - Leonova, V B
AU - Kostanova, E A
AU - Biryukova, M I
AU - Bychkova, A.V.
AU - Konstantinova, M L
AU - Vasilyeva, A D
PY - 2016
DA - 2016/03/01
PB - Pleiades Publishing
SP - 128-131
IS - 1
VL - 467
PMID - 27193716
SN - 1607-6729
SN - 1608-3091
ER -
BibTex |
Cite this
BibTex (up to 50 authors) Copy
@article{2016_Rosenfeld,
author = {M. A. Rosenfeld and A N Shchegolikhin and V B Leonova and E A Kostanova and M I Biryukova and A.V. Bychkova and M L Konstantinova and A D Vasilyeva},
title = {The oxidative modification of cellular fibrin-stabilizing factor},
journal = {Doklady Biochemistry and Biophysics},
year = {2016},
volume = {467},
publisher = {Pleiades Publishing},
month = {mar},
url = {https://doi.org/10.1134/S1607672916020149},
number = {1},
pages = {128--131},
doi = {10.1134/S1607672916020149}
}
MLA
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MLA Copy
Rosenfeld, M. A., et al. “The oxidative modification of cellular fibrin-stabilizing factor.” Doklady Biochemistry and Biophysics, vol. 467, no. 1, Mar. 2016, pp. 128-131. https://doi.org/10.1134/S1607672916020149.