The effect of pregnancy-specific β1-glycoprotein 1 on the transcription factor FOXP3 expression by immunocompetent cells
S. A. Zamorina
1
,
L. S. Litvinova
2
,
K A Yurova
2
,
N A Dunets
2
,
O G Khaziakhmatova
2
,
V P Timganova
1
,
M S Bochkova
1
,
P V Khramtsov
1
,
M.B Rayev
1, 3
Publication type: Journal Article
Publication date: 2016-09-01
scimago Q3
wos Q4
SJR: 0.223
CiteScore: 1.5
Impact factor: 0.7
ISSN: 16076729, 16083091
PubMed ID:
27817017
General Chemistry
Biochemistry
General Medicine
Biophysics
Abstract
The role of human pregnancy-specific β1-glycoprotein (PSG) in the regulation of expression of the transcription factor FOXP3 was studied. It is found that, under conditions of directed induction of phenotypic changes in CD4+ lymphocytes to regulatory T cells (Treg), PSG at high concentrations (10 and 100 μg/mL) increased FOXP3 expression. The evaluation of the spontaneous expression level of FOXP3 mRNA showed that PSG (1 and 100 μg/mL) stimulated the expression of this factor in mononuclear cells and isolated CD4+ lymphocytes. Thus, PSG stimulates FOXP3 expression in immunocompetent cells.
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Zamorina S. A. et al. The effect of pregnancy-specific β1-glycoprotein 1 on the transcription factor FOXP3 expression by immunocompetent cells // Doklady Biochemistry and Biophysics. 2016. Vol. 470. No. 1. pp. 361-363.
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Zamorina S. A., Litvinova L. S., Yurova K. A., Dunets N. A., Khaziakhmatova O. G., Timganova V. P., Bochkova M. S., Khramtsov P. V., Rayev M. The effect of pregnancy-specific β1-glycoprotein 1 on the transcription factor FOXP3 expression by immunocompetent cells // Doklady Biochemistry and Biophysics. 2016. Vol. 470. No. 1. pp. 361-363.
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RIS
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TY - JOUR
DO - 10.1134/S1607672916050161
UR - https://doi.org/10.1134/S1607672916050161
TI - The effect of pregnancy-specific β1-glycoprotein 1 on the transcription factor FOXP3 expression by immunocompetent cells
T2 - Doklady Biochemistry and Biophysics
AU - Zamorina, S. A.
AU - Litvinova, L. S.
AU - Yurova, K A
AU - Dunets, N A
AU - Khaziakhmatova, O G
AU - Timganova, V P
AU - Bochkova, M S
AU - Khramtsov, P V
AU - Rayev, M.B
PY - 2016
DA - 2016/09/01
PB - Pleiades Publishing
SP - 361-363
IS - 1
VL - 470
PMID - 27817017
SN - 1607-6729
SN - 1608-3091
ER -
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BibTex (up to 50 authors)
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@article{2016_Zamorina,
author = {S. A. Zamorina and L. S. Litvinova and K A Yurova and N A Dunets and O G Khaziakhmatova and V P Timganova and M S Bochkova and P V Khramtsov and M.B Rayev},
title = {The effect of pregnancy-specific β1-glycoprotein 1 on the transcription factor FOXP3 expression by immunocompetent cells},
journal = {Doklady Biochemistry and Biophysics},
year = {2016},
volume = {470},
publisher = {Pleiades Publishing},
month = {sep},
url = {https://doi.org/10.1134/S1607672916050161},
number = {1},
pages = {361--363},
doi = {10.1134/S1607672916050161}
}
Cite this
MLA
Copy
Zamorina, S. A., et al. “The effect of pregnancy-specific β1-glycoprotein 1 on the transcription factor FOXP3 expression by immunocompetent cells.” Doklady Biochemistry and Biophysics, vol. 470, no. 1, Sep. 2016, pp. 361-363. https://doi.org/10.1134/S1607672916050161.
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