Peroxide-Induced Oxidative Modification of Hemoglobin
A D Vasilyeva
1
,
L V Yurina
1
,
A. E. Bugrova
1
,
M. I. Indeykina
1, 2
,
D. Y. Azarova
1, 3
,
A.V. Bychkova
1
,
K. I. Akzhigitova
1, 4
,
A. S. Kononikhin
1, 2, 5
,
E. N. Nikolaev
1, 5, 6
,
M. A. Rosenfeld
1
Publication type: Journal Article
Publication date: 2019-05-01
scimago Q3
wos Q4
SJR: 0.223
CiteScore: 1.5
Impact factor: 0.7
ISSN: 16076729, 16083091
PubMed ID:
31367820
General Chemistry
Biochemistry
General Medicine
Biophysics
Abstract
The oxidative modification of human hemoglobin (Hb) treated with hydrogen peroxide was investigated. Using the mass spectrometry method, the oxidized amino acid residues of the hemoglobin molecule were detected: αTrp14, αTyr24, αArg31, αMet32, αTyr42, αHis45, αHis72, αMet76, αPro77, αLys90, αCys104, αTyr140, βHis2, βTrp15, βTrp37, βMet55, βCys93, βCys112, βTyr130, βLys144, and βHis146. The antioxidant potential of the Hb molecule in the intracellular space and in the blood plasma is discussed.
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Vasilyeva A. D. et al. Peroxide-Induced Oxidative Modification of Hemoglobin // Doklady Biochemistry and Biophysics. 2019. Vol. 486. No. 1. pp. 197-200.
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Vasilyeva A. D., Yurina L. V., Bugrova A. E., Indeykina M. I., Azarova D. Y., Bychkova A., Akzhigitova K. I., Kononikhin A. S., Nikolaev E. N., Rosenfeld M. A. Peroxide-Induced Oxidative Modification of Hemoglobin // Doklady Biochemistry and Biophysics. 2019. Vol. 486. No. 1. pp. 197-200.
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TY - JOUR
DO - 10.1134/S1607672919030116
UR - https://doi.org/10.1134/S1607672919030116
TI - Peroxide-Induced Oxidative Modification of Hemoglobin
T2 - Doklady Biochemistry and Biophysics
AU - Vasilyeva, A D
AU - Yurina, L V
AU - Bugrova, A. E.
AU - Indeykina, M. I.
AU - Azarova, D. Y.
AU - Bychkova, A.V.
AU - Akzhigitova, K. I.
AU - Kononikhin, A. S.
AU - Nikolaev, E. N.
AU - Rosenfeld, M. A.
PY - 2019
DA - 2019/05/01
PB - Pleiades Publishing
SP - 197-200
IS - 1
VL - 486
PMID - 31367820
SN - 1607-6729
SN - 1608-3091
ER -
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@article{2019_Vasilyeva,
author = {A D Vasilyeva and L V Yurina and A. E. Bugrova and M. I. Indeykina and D. Y. Azarova and A.V. Bychkova and K. I. Akzhigitova and A. S. Kononikhin and E. N. Nikolaev and M. A. Rosenfeld},
title = {Peroxide-Induced Oxidative Modification of Hemoglobin},
journal = {Doklady Biochemistry and Biophysics},
year = {2019},
volume = {486},
publisher = {Pleiades Publishing},
month = {may},
url = {https://doi.org/10.1134/S1607672919030116},
number = {1},
pages = {197--200},
doi = {10.1134/S1607672919030116}
}
Cite this
MLA
Copy
Vasilyeva, A. D., et al. “Peroxide-Induced Oxidative Modification of Hemoglobin.” Doklady Biochemistry and Biophysics, vol. 486, no. 1, May. 2019, pp. 197-200. https://doi.org/10.1134/S1607672919030116.
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