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Doklady Biochemistry and Biophysics

, том 496 , издание 1 , страницы 5-9

Immortalization of Human Keratinocytes Using the Catalytic Subunit of Telomerase

A K Beilin ^{1, 2}

N G Gurskaya ^{1, 2}

N.A. Evtushenko ²

E V Alpeeva ¹

A V Kosykh ^{1, 2}

V. V. Terskikh ¹

A.V. Vasiliev ^{1, 3}

E A Vorotelyak ^{1, 2, 3}

Скрыть аффилиации авторов Показать аффилиации авторов: 3 аффилиации

Koltzov Institute of Developmental Biology, Russian Academy of Sciences, Moscow, Russia |

Pirogov Russian National Research Medical University, Moscow, Russia |

Moscow State University, Moscow, Russia |

Тип публикации: Journal Article

Дата публикации: 2021-03-10

Pleiades Publishing

Doklady Biochemistry and Biophysics

scimago Q3

wos Q4

БС3

SJR: 0.223

CiteScore: 1.5

Impact factor: 0.7

ISSN: 16076729, 16083091

DOI: 10.1134/S1607672921010014

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PubMed ID: 33689065

General Chemistry

Biochemistry

General Medicine

Biophysics

Краткое описание

A new stable line of human keratinocytes was obtained. The cells have altered morphology, both abnormal chromosomal composition and expression of keratinocyte markers, do not show contact inhibition, could be cultured in various media and have limited stratification ability in vitro. Upon transplantation into nude mice the cells have tumorigenic properties.

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Processes	Processes, 1, 20% Processes 1 публикация, 20%
International Journal of Molecular Sciences	International Journal of Molecular Sciences, 1, 20% International Journal of Molecular Sciences 1 публикация, 20%
Experimental Dermatology	Experimental Dermatology, 1, 20% Experimental Dermatology 1 публикация, 20%
Biomolecules	Biomolecules, 1, 20% Biomolecules 1 публикация, 20%
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Beilin A. K. et al. Immortalization of Human Keratinocytes Using the Catalytic Subunit of Telomerase // Doklady Biochemistry and Biophysics. 2021. Vol. 496. No. 1. pp. 5-9.

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Beilin A. K., Gurskaya N. G., Evtushenko N., Alpeeva E. V., Kosykh A. V., Terskikh V. V., Vasiliev A., Vorotelyak E. A. Immortalization of Human Keratinocytes Using the Catalytic Subunit of Telomerase // Doklady Biochemistry and Biophysics. 2021. Vol. 496. No. 1. pp. 5-9.

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TY - JOUR

DO - 10.1134/S1607672921010014

UR - https://doi.org/10.1134/S1607672921010014

TI - Immortalization of Human Keratinocytes Using the Catalytic Subunit of Telomerase

T2 - Doklady Biochemistry and Biophysics

AU - Beilin, A K

AU - Gurskaya, N G

AU - Evtushenko, N.A.

AU - Alpeeva, E V

AU - Kosykh, A V

AU - Terskikh, V. V.

AU - Vasiliev, A.V.

AU - Vorotelyak, E A

PY - 2021

DA - 2021/03/10

PB - Pleiades Publishing

SP - 5-9

IS - 1

VL - 496

PMID - 33689065

SN - 1607-6729

SN - 1608-3091

ER -

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@article{2021_Beilin,

author = {A K Beilin and N G Gurskaya and N.A. Evtushenko and E V Alpeeva and A V Kosykh and V. V. Terskikh and A.V. Vasiliev and E A Vorotelyak},

title = {Immortalization of Human Keratinocytes Using the Catalytic Subunit of Telomerase},

journal = {Doklady Biochemistry and Biophysics},

year = {2021},

volume = {496},

publisher = {Pleiades Publishing},

month = {mar},

url = {https://doi.org/10.1134/S1607672921010014},

number = {1},

pages = {5--9},

doi = {10.1134/S1607672921010014}

}

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Beilin, A. K., et al. “Immortalization of Human Keratinocytes Using the Catalytic Subunit of Telomerase.” Doklady Biochemistry and Biophysics, vol. 496, no. 1, Mar. 2021, pp. 5-9. https://doi.org/10.1134/S1607672921010014.