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Open access
volume 496 issue 1 pages 5-9

Immortalization of Human Keratinocytes Using the Catalytic Subunit of Telomerase

Publication typeJournal Article
Publication date2021-03-10
scimago Q3
wos Q4
SJR0.223
CiteScore1.5
Impact factor0.7
ISSN16076729, 16083091
General Chemistry
Biochemistry
General Medicine
Biophysics
Abstract

A new stable line of human keratinocytes was obtained. The cells have altered morphology, both abnormal chromosomal composition and expression of keratinocyte markers, do not show contact inhibition, could be cultured in various media and have limited stratification ability in vitro. Upon transplantation into nude mice the cells have tumorigenic properties.

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GOST Copy
Beilin A. K. et al. Immortalization of Human Keratinocytes Using the Catalytic Subunit of Telomerase // Doklady Biochemistry and Biophysics. 2021. Vol. 496. No. 1. pp. 5-9.
GOST all authors (up to 50) Copy
Beilin A. K., Gurskaya N. G., Evtushenko N., Alpeeva E. V., Kosykh A. V., Terskikh V. V., Vasiliev A., Vorotelyak E. A. Immortalization of Human Keratinocytes Using the Catalytic Subunit of Telomerase // Doklady Biochemistry and Biophysics. 2021. Vol. 496. No. 1. pp. 5-9.
RIS |
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RIS Copy
TY - JOUR
DO - 10.1134/S1607672921010014
UR - https://doi.org/10.1134/S1607672921010014
TI - Immortalization of Human Keratinocytes Using the Catalytic Subunit of Telomerase
T2 - Doklady Biochemistry and Biophysics
AU - Beilin, A K
AU - Gurskaya, N G
AU - Evtushenko, N.A.
AU - Alpeeva, E V
AU - Kosykh, A V
AU - Terskikh, V. V.
AU - Vasiliev, A.V.
AU - Vorotelyak, E A
PY - 2021
DA - 2021/03/10
PB - Pleiades Publishing
SP - 5-9
IS - 1
VL - 496
PMID - 33689065
SN - 1607-6729
SN - 1608-3091
ER -
BibTex |
Cite this
BibTex (up to 50 authors) Copy
@article{2021_Beilin,
author = {A K Beilin and N G Gurskaya and N.A. Evtushenko and E V Alpeeva and A V Kosykh and V. V. Terskikh and A.V. Vasiliev and E A Vorotelyak},
title = {Immortalization of Human Keratinocytes Using the Catalytic Subunit of Telomerase},
journal = {Doklady Biochemistry and Biophysics},
year = {2021},
volume = {496},
publisher = {Pleiades Publishing},
month = {mar},
url = {https://doi.org/10.1134/S1607672921010014},
number = {1},
pages = {5--9},
doi = {10.1134/S1607672921010014}
}
MLA
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MLA Copy
Beilin, A. K., et al. “Immortalization of Human Keratinocytes Using the Catalytic Subunit of Telomerase.” Doklady Biochemistry and Biophysics, vol. 496, no. 1, Mar. 2021, pp. 5-9. https://doi.org/10.1134/S1607672921010014.
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