Graphene Oxide Nanoparticels Interaction with Jurkat Cell Line in Cell-IQ System.
S. A. Zamorina
1
,
P V Khramtsov
1
,
M.B Rayev
1
,
V P Timganova
1
,
M S Bochkova
1
,
A I Nechaev
2
,
E O Shunkin
3
,
O G Khaziakhmatova
3
,
V V Malaschenko
3
,
L. S. Litvinova
3
1
2
Тип публикации: Journal Article
Дата публикации: 2021-11-01
scimago Q3
wos Q4
БС3
SJR: 0.223
CiteScore: 1.5
Impact factor: 0.7
ISSN: 16076729, 16083091
PubMed ID:
34966968
General Chemistry
Biochemistry
General Medicine
Biophysics
Краткое описание
In recent years, materials based on graphene oxide (GO) have been actively studied for their use in biomedicine. The aim of our study was to investigate the increase in cell mass and viability of Jurkat tumor line T cells during 24 h of contact with GO nanoparticles in the Cell-IQ system of intravital observation. We used nanoparticles of different sizes coated with linear or branched polyethylene glycol (PEG) at concentrations of 5 and 25 μg/mL. It was shown for the first time that direct contact with GO nanoparticles reduced the growth in cell mass at the visualization points by more than twofold, regardless of nanoparticle size and concentration. Moreover, the number of live cells in the culture decreased by 5–9% after 24 h of monitoring. Thus, PEG-coated GO nanoparticles were found to suppress the proliferation and viability of Jurkat cell line T lymphocytes.
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Zamorina S. A. et al. Graphene Oxide Nanoparticels Interaction with Jurkat Cell Line in Cell-IQ System. // Doklady Biochemistry and Biophysics. 2021. Vol. 501. No. 1. pp. 438-443.
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Zamorina S. A., Khramtsov P. V., Rayev M., Timganova V. P., Bochkova M. S., Nechaev A. I., Shunkin E. O., Khaziakhmatova O. G., Malaschenko V. V., Litvinova L. S. Graphene Oxide Nanoparticels Interaction with Jurkat Cell Line in Cell-IQ System. // Doklady Biochemistry and Biophysics. 2021. Vol. 501. No. 1. pp. 438-443.
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TY - JOUR
DO - 10.1134/S1607672921060089
UR - https://doi.org/10.1134/S1607672921060089
TI - Graphene Oxide Nanoparticels Interaction with Jurkat Cell Line in Cell-IQ System.
T2 - Doklady Biochemistry and Biophysics
AU - Zamorina, S. A.
AU - Khramtsov, P V
AU - Rayev, M.B
AU - Timganova, V P
AU - Bochkova, M S
AU - Nechaev, A I
AU - Shunkin, E O
AU - Khaziakhmatova, O G
AU - Malaschenko, V V
AU - Litvinova, L. S.
PY - 2021
DA - 2021/11/01
PB - Pleiades Publishing
SP - 438-443
IS - 1
VL - 501
PMID - 34966968
SN - 1607-6729
SN - 1608-3091
ER -
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@article{2021_Zamorina,
author = {S. A. Zamorina and P V Khramtsov and M.B Rayev and V P Timganova and M S Bochkova and A I Nechaev and E O Shunkin and O G Khaziakhmatova and V V Malaschenko and L. S. Litvinova},
title = {Graphene Oxide Nanoparticels Interaction with Jurkat Cell Line in Cell-IQ System.},
journal = {Doklady Biochemistry and Biophysics},
year = {2021},
volume = {501},
publisher = {Pleiades Publishing},
month = {nov},
url = {https://doi.org/10.1134/S1607672921060089},
number = {1},
pages = {438--443},
doi = {10.1134/S1607672921060089}
}
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MLA
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Zamorina, S. A., et al. “Graphene Oxide Nanoparticels Interaction with Jurkat Cell Line in Cell-IQ System..” Doklady Biochemistry and Biophysics, vol. 501, no. 1, Nov. 2021, pp. 438-443. https://doi.org/10.1134/S1607672921060089.
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