volume 7 issue 5-6 pages 302-307

Estimation of membrane activity of water-soluble polysubstituted fullerene derivatives by luminescence methods

D A Poletaeva 1
R A Kotelnikova 1
D V Mischenko 1
A Yu Rybkin 1
A. V. Smolina 1
I. I. Faingold 1
P A Troshin 1
A B Kornev 1
E A Khakina 1
A. I. Kotelnikov 1
Publication typeJournal Article
Publication date2012-05-01
SJR
CiteScore
Impact factor
ISSN19950780, 19950799
Condensed Matter Physics
General Materials Science
General Engineering
Abstract
Patterns of the interaction between water-soluble polysubstituted fullerene derivatives (PFDs) and the lipid bilayer of phosphatidylcholine liposomes were investigated by applying triplet and fluorescent probes. Objective quantitative criteria have been proposed for the evaluation of membranotropic action of chemical substances, notably, fullerene derivatives that quench fluorescent probes with different localizations within the membrane. Thus, the defined criteria are the rate constants for the quenching of the fluorescence of triplet probes and the equilibrium constants for PFD-probe complexes, which characterize their stability. The localization of PFDs in the membrane was determined by comparing rate constants for the quenching of eosin phosphorescence and equilibrium constants for PFD-chromophore complexes. In addition, the efficiency of the interaction of PFDs with various sites of the phospholipid membrane has been seen to depend on the charge of addends that are attached to the polysubstituted derivatives.
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GOST Copy
Poletaeva D. A. et al. Estimation of membrane activity of water-soluble polysubstituted fullerene derivatives by luminescence methods // Nanotechnologies in Russia. 2012. Vol. 7. No. 5-6. pp. 302-307.
GOST all authors (up to 50) Copy
Poletaeva D. A., Kotelnikova R. A., Mischenko D. V., Rybkin A. Yu., Smolina A. V., Faingold I. I., Troshin P. A., Kornev A. B., Khakina E. A., Kotelnikov A. I. Estimation of membrane activity of water-soluble polysubstituted fullerene derivatives by luminescence methods // Nanotechnologies in Russia. 2012. Vol. 7. No. 5-6. pp. 302-307.
RIS |
Cite this
RIS Copy
TY - JOUR
DO - 10.1134/S1995078012030135
UR - https://doi.org/10.1134/S1995078012030135
TI - Estimation of membrane activity of water-soluble polysubstituted fullerene derivatives by luminescence methods
T2 - Nanotechnologies in Russia
AU - Poletaeva, D A
AU - Kotelnikova, R A
AU - Mischenko, D V
AU - Rybkin, A Yu
AU - Smolina, A. V.
AU - Faingold, I. I.
AU - Troshin, P A
AU - Kornev, A B
AU - Khakina, E A
AU - Kotelnikov, A. I.
PY - 2012
DA - 2012/05/01
PB - Pleiades Publishing
SP - 302-307
IS - 5-6
VL - 7
SN - 1995-0780
SN - 1995-0799
ER -
BibTex |
Cite this
BibTex (up to 50 authors) Copy
@article{2012_Poletaeva,
author = {D A Poletaeva and R A Kotelnikova and D V Mischenko and A Yu Rybkin and A. V. Smolina and I. I. Faingold and P A Troshin and A B Kornev and E A Khakina and A. I. Kotelnikov},
title = {Estimation of membrane activity of water-soluble polysubstituted fullerene derivatives by luminescence methods},
journal = {Nanotechnologies in Russia},
year = {2012},
volume = {7},
publisher = {Pleiades Publishing},
month = {may},
url = {https://doi.org/10.1134/S1995078012030135},
number = {5-6},
pages = {302--307},
doi = {10.1134/S1995078012030135}
}
MLA
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MLA Copy
Poletaeva, D. A., et al. “Estimation of membrane activity of water-soluble polysubstituted fullerene derivatives by luminescence methods.” Nanotechnologies in Russia, vol. 7, no. 5-6, May. 2012, pp. 302-307. https://doi.org/10.1134/S1995078012030135.