Elemental Boron Nanoparticles: Production by Ultrasonication in Aqueous Medium and Application in Boron Neutron Capture Therapy
S A Uspenskii
1, 2
,
P A Khaptakhanova
1, 2
,
A A Zaboronok
3, 4
,
T S Kurkin
1
,
O Yu Volkova
5
,
L V Mechetina
5
,
A V Taranin
5
,
V V Kanygin
4
,
Akira Matsumura
3
,
S Yu Taskaev
6
1
Publication type: Journal Article
Publication date: 2020-03-01
scimago Q3
wos Q4
SJR: 0.205
CiteScore: 1.3
Impact factor: 1.0
ISSN: 00125008, 16083113
General Chemistry
Abstract
A method for producing elemental boron nanoparticles with a size of less than 100 nm by ultrasonic dispersion in a liquid medium and subsequent cascade fractionation is described. The resulting boron nanoparticles were used as a target for boron neutron capture therapy (BNCT). According to the results of an experimental preclinical study of BNCT with the synthesized boron nanoparticles, neutron irradiation for 1 h of T98G human glioma cells pre-incubated in a medium with boron nanoparticles (10, 20, and 40 ppm in terms of boron-10 isotope) leads to a significant suppression of cell viability.
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Uspenskii S. A. et al. Elemental Boron Nanoparticles: Production by Ultrasonication in Aqueous Medium and Application in Boron Neutron Capture Therapy // Doklady Chemistry. 2020. Vol. 491. No. 1. pp. 45-48.
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Uspenskii S. A., Khaptakhanova P. A., Zaboronok A. A., Kurkin T. S., Volkova O. Yu., Mechetina L. V., Taranin A. V., Kanygin V. V., Matsumura A., Taskaev S. Yu. Elemental Boron Nanoparticles: Production by Ultrasonication in Aqueous Medium and Application in Boron Neutron Capture Therapy // Doklady Chemistry. 2020. Vol. 491. No. 1. pp. 45-48.
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TY - JOUR
DO - 10.1134/s0012500820030027
UR - https://doi.org/10.1134/s0012500820030027
TI - Elemental Boron Nanoparticles: Production by Ultrasonication in Aqueous Medium and Application in Boron Neutron Capture Therapy
T2 - Doklady Chemistry
AU - Uspenskii, S A
AU - Khaptakhanova, P A
AU - Zaboronok, A A
AU - Kurkin, T S
AU - Volkova, O Yu
AU - Mechetina, L V
AU - Taranin, A V
AU - Kanygin, V V
AU - Matsumura, Akira
AU - Taskaev, S Yu
PY - 2020
DA - 2020/03/01
PB - Pleiades Publishing
SP - 45-48
IS - 1
VL - 491
SN - 0012-5008
SN - 1608-3113
ER -
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@article{2020_Uspenskii,
author = {S A Uspenskii and P A Khaptakhanova and A A Zaboronok and T S Kurkin and O Yu Volkova and L V Mechetina and A V Taranin and V V Kanygin and Akira Matsumura and S Yu Taskaev},
title = {Elemental Boron Nanoparticles: Production by Ultrasonication in Aqueous Medium and Application in Boron Neutron Capture Therapy},
journal = {Doklady Chemistry},
year = {2020},
volume = {491},
publisher = {Pleiades Publishing},
month = {mar},
url = {https://doi.org/10.1134/s0012500820030027},
number = {1},
pages = {45--48},
doi = {10.1134/s0012500820030027}
}
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MLA
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Uspenskii, S. A., et al. “Elemental Boron Nanoparticles: Production by Ultrasonication in Aqueous Medium and Application in Boron Neutron Capture Therapy.” Doklady Chemistry, vol. 491, no. 1, Mar. 2020, pp. 45-48. https://doi.org/10.1134/s0012500820030027.