Synthesis and Prediction of Antitumor Activity of New Fused Pyrano[3,4-c]pyridines and Pyrano[4′,3′:4,5]pyrido[2,3-d]pyrimidines
Publication type: Journal Article
Publication date: 2022-03-01
scimago Q4
wos Q4
SJR: 0.179
CiteScore: 1.4
Impact factor: 0.8
ISSN: 10703632, 16083350
General Chemistry
Abstract
One-pot methods were developed for the preparation of 6-amino-3-isopropyl-7-aryl substituted-8-thioxo(oxo)pyrano[3,4-c]pyridines derivatives. The latter served as starting materials for the synthesis of a new pyrano[4′,3′:4,5]pyrido[2,3-d]pyrimidine heterosystems. The proposed mechanisms of one-pot reactions were presented. Antitumor activity of new synthesized compounds was predicted by in silico methods.
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Dashyan S. S. et al. Synthesis and Prediction of Antitumor Activity of New Fused Pyrano[3,4-c]pyridines and Pyrano[4′,3′:4,5]pyrido[2,3-d]pyrimidines // Russian Journal of General Chemistry. 2022. Vol. 92. No. 3. pp. 383-392.
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Dashyan S. S., Paronikyan E. G., Ayvazyan A. S., Mamyan S. S., Hunanyan L. S. Synthesis and Prediction of Antitumor Activity of New Fused Pyrano[3,4-c]pyridines and Pyrano[4′,3′:4,5]pyrido[2,3-d]pyrimidines // Russian Journal of General Chemistry. 2022. Vol. 92. No. 3. pp. 383-392.
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TY - JOUR
DO - 10.1134/s1070363222030069
UR - https://doi.org/10.1134/s1070363222030069
TI - Synthesis and Prediction of Antitumor Activity of New Fused Pyrano[3,4-c]pyridines and Pyrano[4′,3′:4,5]pyrido[2,3-d]pyrimidines
T2 - Russian Journal of General Chemistry
AU - Dashyan, Sh Sh
AU - Paronikyan, E G
AU - Ayvazyan, A S
AU - Mamyan, S S
AU - Hunanyan, L S
PY - 2022
DA - 2022/03/01
PB - Pleiades Publishing
SP - 383-392
IS - 3
VL - 92
SN - 1070-3632
SN - 1608-3350
ER -
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@article{2022_Dashyan,
author = {Sh Sh Dashyan and E G Paronikyan and A S Ayvazyan and S S Mamyan and L S Hunanyan},
title = {Synthesis and Prediction of Antitumor Activity of New Fused Pyrano[3,4-c]pyridines and Pyrano[4′,3′:4,5]pyrido[2,3-d]pyrimidines},
journal = {Russian Journal of General Chemistry},
year = {2022},
volume = {92},
publisher = {Pleiades Publishing},
month = {mar},
url = {https://doi.org/10.1134/s1070363222030069},
number = {3},
pages = {383--392},
doi = {10.1134/s1070363222030069}
}
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MLA
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Dashyan, Sh Sh, et al. “Synthesis and Prediction of Antitumor Activity of New Fused Pyrano[3,4-c]pyridines and Pyrano[4′,3′:4,5]pyrido[2,3-d]pyrimidines.” Russian Journal of General Chemistry, vol. 92, no. 3, Mar. 2022, pp. 383-392. https://doi.org/10.1134/s1070363222030069.