Synthesis of Novel Benzothiophene Derivatives via Cyclization Reactions
Тип публикации: Journal Article
Дата публикации: 2020-07-01
scimago Q4
wos Q4
БС3
SJR: 0.190
CiteScore: 1.3
Impact factor: 0.9
ISSN: 10704280, 16083393
Organic Chemistry
Краткое описание
The Sonogashira cross coupling reaction of 2-bromo-5-(4-methoxyphenyl)thiophene and 1-ethynyl-2-(methylsulfanyl)benzene gave 2-(4-methoxyphenyl)-5-{[2-(methylsulfanyl)phenyl]ethynyl}thiophene which was subjected to electrophilic cyclization by the action of iodine to obtain 3-iodo-2-[5-(4-methoxyphenyl)thiophen-2-yl]-1-benzothiophene. Stille and Sonogashira coupling reactions of the latter afforded a series of new 3-substituted 2-[5-(4-methoxyphenyl)thiophen-2-yl]-1-benzothiophene derivatives of potential pharmacological interest.
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Hama A. K. et al. Synthesis of Novel Benzothiophene Derivatives via Cyclization Reactions // Russian Journal of Organic Chemistry. 2020. Vol. 56. No. 7. pp. 1272-1278.
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Hama A. K., Algso M. A. S., Kavak E., Kivrak A. Synthesis of Novel Benzothiophene Derivatives via Cyclization Reactions // Russian Journal of Organic Chemistry. 2020. Vol. 56. No. 7. pp. 1272-1278.
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TY - JOUR
DO - 10.1134/s1070428020070222
UR - https://doi.org/10.1134/s1070428020070222
TI - Synthesis of Novel Benzothiophene Derivatives via Cyclization Reactions
T2 - Russian Journal of Organic Chemistry
AU - Hama, A K
AU - Algso, M A S
AU - Kavak, E.
AU - Kivrak, A
PY - 2020
DA - 2020/07/01
PB - Pleiades Publishing
SP - 1272-1278
IS - 7
VL - 56
SN - 1070-4280
SN - 1608-3393
ER -
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@article{2020_Hama,
author = {A K Hama and M A S Algso and E. Kavak and A Kivrak},
title = {Synthesis of Novel Benzothiophene Derivatives via Cyclization Reactions},
journal = {Russian Journal of Organic Chemistry},
year = {2020},
volume = {56},
publisher = {Pleiades Publishing},
month = {jul},
url = {https://doi.org/10.1134/s1070428020070222},
number = {7},
pages = {1272--1278},
doi = {10.1134/s1070428020070222}
}
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Hama, A. K., et al. “Synthesis of Novel Benzothiophene Derivatives via Cyclization Reactions.” Russian Journal of Organic Chemistry, vol. 56, no. 7, Jul. 2020, pp. 1272-1278. https://doi.org/10.1134/s1070428020070222.