Russian Journal of Organic Chemistry, volume 57, issue 10, pages 1700-1718
An Overview on Biological Importance of Pyrrolone and Pyrrolidinone Derivatives as Promising Scaffolds
1
Glocal School of Pharmacy, Glocal University, Saharanpur, India
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Publication type: Journal Article
Publication date: 2021-10-01
Journal:
Russian Journal of Organic Chemistry
Quartile SCImago
Q4
Quartile WOS
Q4
Impact factor: 0.8
ISSN: 10704280, 16083393
Organic Chemistry
Abstract
Pyrrolones and pyrrolidinones are five-membered heterocycles and are versatile lead compounds for designing powerful bioactive agents. Pyrrolone and pyrrolidinone moieties are among the most essential heterocyclic pharmacophores inducing prominent pharmaceutical effects. Therefore, researchers paid attention to synthesize various pyrrolone and pyrrolidinone derivatives. Numerous methods for the synthesis of pyrrolones and pyrrolidinones offer a great scope in the field of medicinal chemistry. This attractive group of compounds has diverse biological activities like antimicrobial, anti-inflammatory, anticancer, antidepressant, anticonvulsant, etc. The purpose of this review is to classify broad information on the chemistry and pharmaceutical effects of pyrrolones and pyrrolidinones to open a new perspective for future studies. It is clear that a wide spectrum of pyrrolones and pyrrolidinone derivatives have been synthesized and that most of them have various significant biological activities. Thus, these derivatives can be used for the future development of novel compounds active against different infections and diseases.
Top-30
Citations by journals
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1
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Journal of Organic Chemistry
2 publications, 33.33%
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Organic Chemistry Frontiers
1 publication, 16.67%
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Chemical Data Collections
1 publication, 16.67%
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Marine Drugs
1 publication, 16.67%
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Russian Journal of Organic Chemistry
1 publication, 16.67%
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2
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Citations by publishers
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1
2
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American Chemical Society (ACS)
2 publications, 33.33%
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Royal Society of Chemistry (RSC)
1 publication, 16.67%
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Elsevier
1 publication, 16.67%
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Multidisciplinary Digital Publishing Institute (MDPI)
1 publication, 16.67%
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Pleiades Publishing
1 publication, 16.67%
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2
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- We do not take into account publications without a DOI.
- Statistics recalculated only for publications connected to researchers, organizations and labs registered on the platform.
- Statistics recalculated weekly.
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Asif M., alghamdi S. An Overview on Biological Importance of Pyrrolone and Pyrrolidinone Derivatives as Promising Scaffolds // Russian Journal of Organic Chemistry. 2021. Vol. 57. No. 10. pp. 1700-1718.
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Asif M., alghamdi S. An Overview on Biological Importance of Pyrrolone and Pyrrolidinone Derivatives as Promising Scaffolds // Russian Journal of Organic Chemistry. 2021. Vol. 57. No. 10. pp. 1700-1718.
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TY - JOUR
DO - 10.1134/s1070428021100201
UR - https://doi.org/10.1134/s1070428021100201
TI - An Overview on Biological Importance of Pyrrolone and Pyrrolidinone Derivatives as Promising Scaffolds
T2 - Russian Journal of Organic Chemistry
AU - Asif, M.
AU - alghamdi, S.
PY - 2021
DA - 2021/10/01 00:00:00
PB - Pleiades Publishing
SP - 1700-1718
IS - 10
VL - 57
SN - 1070-4280
SN - 1608-3393
ER -
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@article{2021_Asif,
author = {M. Asif and S. alghamdi},
title = {An Overview on Biological Importance of Pyrrolone and Pyrrolidinone Derivatives as Promising Scaffolds},
journal = {Russian Journal of Organic Chemistry},
year = {2021},
volume = {57},
publisher = {Pleiades Publishing},
month = {oct},
url = {https://doi.org/10.1134/s1070428021100201},
number = {10},
pages = {1700--1718},
doi = {10.1134/s1070428021100201}
}
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MLA
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Asif, M., and S. alghamdi. “An Overview on Biological Importance of Pyrrolone and Pyrrolidinone Derivatives as Promising Scaffolds.” Russian Journal of Organic Chemistry, vol. 57, no. 10, Oct. 2021, pp. 1700-1718. https://doi.org/10.1134/s1070428021100201.