Sodium Alginate Interpolymer Complexes as a Platform for pH-Tunable Drug Carriers
Publication type: Journal Article
Publication date: 2020-11-01
scimago Q3
wos Q4
SJR: 0.234
CiteScore: 1.8
Impact factor: 1.0
ISSN: 15600904, 15556123
Materials Chemistry
Ceramics and Composites
Polymers and Plastics
Abstract
The method of obtaining hydrogels from sodium alginate interpolymer complexes with the copolymer of methyl vinyl ether and maleic anhydride is developed. It is shown that the interpolymer network is formed via hydrogen bonding between the hydroxyl groups of alginate and the carboxyl groups of the copolymer. The structure of the network, namely, the type of bonds and their density, is primarily controlled by the treatment temperature of the polymer mixture. Using lidocaine as a model drug, it is demonstrated that these complexes can be used as a platform for рН-tunable drug delivery systems.
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Gorshkova M. Yu. et al. Sodium Alginate Interpolymer Complexes as a Platform for pH-Tunable Drug Carriers // Polymer Science - Series B. 2020. Vol. 62. No. 6. pp. 678-684.
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Gorshkova M. Yu., Volkova I. F., Grigoryan E. S., Valuev L. I. Sodium Alginate Interpolymer Complexes as a Platform for pH-Tunable Drug Carriers // Polymer Science - Series B. 2020. Vol. 62. No. 6. pp. 678-684.
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TY - JOUR
DO - 10.1134/s1560090420060044
UR - https://doi.org/10.1134/s1560090420060044
TI - Sodium Alginate Interpolymer Complexes as a Platform for pH-Tunable Drug Carriers
T2 - Polymer Science - Series B
AU - Gorshkova, M Yu
AU - Volkova, I F
AU - Grigoryan, E S
AU - Valuev, L. I.
PY - 2020
DA - 2020/11/01
PB - Pleiades Publishing
SP - 678-684
IS - 6
VL - 62
SN - 1560-0904
SN - 1555-6123
ER -
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BibTex (up to 50 authors)
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@article{2020_Gorshkova,
author = {M Yu Gorshkova and I F Volkova and E S Grigoryan and L. I. Valuev},
title = {Sodium Alginate Interpolymer Complexes as a Platform for pH-Tunable Drug Carriers},
journal = {Polymer Science - Series B},
year = {2020},
volume = {62},
publisher = {Pleiades Publishing},
month = {nov},
url = {https://doi.org/10.1134/s1560090420060044},
number = {6},
pages = {678--684},
doi = {10.1134/s1560090420060044}
}
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MLA
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Gorshkova, M. Yu., et al. “Sodium Alginate Interpolymer Complexes as a Platform for pH-Tunable Drug Carriers.” Polymer Science - Series B, vol. 62, no. 6, Nov. 2020, pp. 678-684. https://doi.org/10.1134/s1560090420060044.