3-Aminocyclobutane-1-carboxylic acid: Synthesis and some neurochemical properties
Publication type: Journal Article
Publication date: 2019-02-22
SJR: —
CiteScore: —
Impact factor: —
ISSN: 00100765, 12126950
General Chemistry
Abstract
The paper describes synthesis of 3-amino-cyclobutane-1-carboxylic acid and its resolution into diastereoisomers. Preparations of cerebral 4-aminobutyrate: 2-oxoglutarate aminotransferase were capable of utilizing both diastereoisomers for transamination. In the uptake of (2,3-H3)-4-aminobutyric acid by slices of rat cerebral tissue the two isomers fUllction as simple competitive inhibitors. The inhibitary potency of the uptake and the utilization in transamination of the cis isomer was higher than that of the trans isomer. This reflects specific steric pre-requisites for the two processes.
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Total citations:
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Citations from 2024:
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(12.5%)
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GOST
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Šafanda J., Sobotka P. 3-Aminocyclobutane-1-carboxylic acid: Synthesis and some neurochemical properties // Collection of Czechoslovak Chemical Communications. 2019. Vol. 47. No. 9. pp. 2440-2447.
GOST all authors (up to 50)
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Šafanda J., Sobotka P. 3-Aminocyclobutane-1-carboxylic acid: Synthesis and some neurochemical properties // Collection of Czechoslovak Chemical Communications. 2019. Vol. 47. No. 9. pp. 2440-2447.
Cite this
RIS
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TY - JOUR
DO - 10.1135/cccc19822440
UR - https://doi.org/10.1135/cccc19822440
TI - 3-Aminocyclobutane-1-carboxylic acid: Synthesis and some neurochemical properties
T2 - Collection of Czechoslovak Chemical Communications
AU - Šafanda, J
AU - Sobotka, Pavel
PY - 2019
DA - 2019/02/22
PB - Institute of Organic Chemistry & Biochemistry
SP - 2440-2447
IS - 9
VL - 47
SN - 0010-0765
SN - 1212-6950
ER -
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BibTex (up to 50 authors)
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@article{2019_Šafanda,
author = {J Šafanda and Pavel Sobotka},
title = {3-Aminocyclobutane-1-carboxylic acid: Synthesis and some neurochemical properties},
journal = {Collection of Czechoslovak Chemical Communications},
year = {2019},
volume = {47},
publisher = {Institute of Organic Chemistry & Biochemistry},
month = {feb},
url = {https://doi.org/10.1135/cccc19822440},
number = {9},
pages = {2440--2447},
doi = {10.1135/cccc19822440}
}
Cite this
MLA
Copy
Šafanda, J., and Pavel Sobotka. “3-Aminocyclobutane-1-carboxylic acid: Synthesis and some neurochemical properties.” Collection of Czechoslovak Chemical Communications, vol. 47, no. 9, Feb. 2019, pp. 2440-2447. https://doi.org/10.1135/cccc19822440.