Journal of Neurology, Neurosurgery and Psychiatry, volume 85, issue 7, pages 716-720

Complications to invasive epilepsy surgery workup with subdural and depth electrodes: a prospective population-based observational study

Publication typeJournal Article
Publication date2013-11-29
BMJ
BMJ
Quartile SCImago
Q1
Quartile WOS
Q1
Impact factor8.7
ISSN00223050, 1468330X
Psychiatry and Mental health
Surgery
Neurology (clinical)
Abstract

Objective

In some patients who undergo presurgical workup for drug-resistant epilepsy invasive seizure monitoring is needed to define the seizure onset zone and delineate eloquent cortex. Such procedures carry risks for complications causing permanent morbidity and even mortality. In this study, prospective data on complications in a national population-based sample were analysed.

Design

Complication data from the prospective Swedish National Epilepsy Surgery Register were analysed for 271 patients in whom therapeutic surgery was preceded by invasive monitoring 1996–2010.

Results

Complications occurred in 13/271 patients (4.8%). Subdural grids carried the highest risk of complications (7.4%). There was no surgical mortality or permanent morbidity. Subdural haematomas were most common (n=7) followed by epidural haematomas (n=3). Valproate treatment and having a haematoma was associated with an OR of 1.53 (CI 0.38 to 6.12) compared to having a haematoma without valproate treatment. Having a complication during invasive monitoring was associated with a significant OR of 6.27 (CI 1.32 to 29.9) of also having a complication at therapeutic surgery compared to the risk of having a complication only at surgery.

Conclusions

In this prospective population-based epilepsy surgery series, the most common complications were haematomas, and subdural grids carried the highest risk. Close supervision and rapid interventions led to avoidance of permanent morbidity. The clinical implications of the slightly increased risk of haematomas with valproate treatment needs further investigation as does the finding of an increased risk for complications at epilepsy surgery for patients who had a complication during invasive monitoring.

Top-30

Journals

1
2
3
4
5
6
7
Epilepsia
7 publications, 9.86%
World Neurosurgery
4 publications, 5.63%
Epilepsy and Behavior
3 publications, 4.23%
Seizure : the journal of the British Epilepsy Association
3 publications, 4.23%
Stereotactic and Functional Neurosurgery
2 publications, 2.82%
Neurology
2 publications, 2.82%
Current Opinion in Neurology
2 publications, 2.82%
Neurosurgery
2 publications, 2.82%
Journal of Neurosurgery
2 publications, 2.82%
Acta Neurochirurgica
2 publications, 2.82%
Epilepsy Research
2 publications, 2.82%
JAMA Neurology
2 publications, 2.82%
Current Medical Imaging Reviews
1 publication, 1.41%
Journal of Neurosurgery: Pediatrics
1 publication, 1.41%
Brain Sciences
1 publication, 1.41%
Micromachines
1 publication, 1.41%
Der Nervenarzt
1 publication, 1.41%
Neurotherapeutics
1 publication, 1.41%
Neuroradiology
1 publication, 1.41%
Journal of Neurology
1 publication, 1.41%
Clinical Neurophysiology
1 publication, 1.41%
Annals of Medicine and Surgery
1 publication, 1.41%
Neurobiology of Disease
1 publication, 1.41%
Biomedical Physics and Engineering Express
1 publication, 1.41%
PLoS ONE
1 publication, 1.41%
Neuron
1 publication, 1.41%
Advanced Functional Materials
1 publication, 1.41%
Artificial Organs
1 publication, 1.41%
Neurological Research
1 publication, 1.41%
1
2
3
4
5
6
7

Publishers

2
4
6
8
10
12
14
16
18
20
Elsevier
19 publications, 26.76%
Wiley
11 publications, 15.49%
Springer Nature
9 publications, 12.68%
Ovid Technologies (Wolters Kluwer Health)
6 publications, 8.45%
Journal of Neurosurgery Publishing Group (JNSPG)
3 publications, 4.23%
MDPI
3 publications, 4.23%
S. Karger AG
2 publications, 2.82%
American Medical Association (AMA)
2 publications, 2.82%
Bentham Science Publishers Ltd.
1 publication, 1.41%
IOP Publishing
1 publication, 1.41%
Public Library of Science (PLoS)
1 publication, 1.41%
Taylor & Francis
1 publication, 1.41%
American Physiological Society
1 publication, 1.41%
Proceedings of the National Academy of Sciences (PNAS)
1 publication, 1.41%
Siberian State Medical University
1 publication, 1.41%
Publishing House ABV Press
1 publication, 1.41%
Media Sphere Publishing House
1 publication, 1.41%
Cambridge University Press
1 publication, 1.41%
American Association for the Advancement of Science (AAAS)
1 publication, 1.41%
Cold Spring Harbor Laboratory
1 publication, 1.41%
2
4
6
8
10
12
14
16
18
20
  • We do not take into account publications without a DOI.
  • Statistics recalculated only for publications connected to researchers, organizations and labs registered on the platform.
  • Statistics recalculated weekly.

Are you a researcher?

Create a profile to get free access to personal recommendations for colleagues and new articles.
Metrics
Share
Cite this
GOST |
Cite this
GOST Copy
Hedegard E. et al. Complications to invasive epilepsy surgery workup with subdural and depth electrodes: a prospective population-based observational study // Journal of Neurology, Neurosurgery and Psychiatry. 2013. Vol. 85. No. 7. pp. 716-720.
GOST all authors (up to 50) Copy
Hedegard E., Bjellvi J., Edelvik A., Rydenhag B., Flink R., Malmgren K. Complications to invasive epilepsy surgery workup with subdural and depth electrodes: a prospective population-based observational study // Journal of Neurology, Neurosurgery and Psychiatry. 2013. Vol. 85. No. 7. pp. 716-720.
RIS |
Cite this
RIS Copy
TY - JOUR
DO - 10.1136/jnnp-2013-306465
UR - https://doi.org/10.1136/jnnp-2013-306465
TI - Complications to invasive epilepsy surgery workup with subdural and depth electrodes: a prospective population-based observational study
T2 - Journal of Neurology, Neurosurgery and Psychiatry
AU - Hedegard, E
AU - Bjellvi, J
AU - Edelvik, A
AU - Rydenhag, B.
AU - Flink, R.
AU - Malmgren, K
PY - 2013
DA - 2013/11/29
PB - BMJ
SP - 716-720
IS - 7
VL - 85
SN - 0022-3050
SN - 1468-330X
ER -
BibTex |
Cite this
BibTex Copy
@article{2013_Hedegard,
author = {E Hedegard and J Bjellvi and A Edelvik and B. Rydenhag and R. Flink and K Malmgren},
title = {Complications to invasive epilepsy surgery workup with subdural and depth electrodes: a prospective population-based observational study},
journal = {Journal of Neurology, Neurosurgery and Psychiatry},
year = {2013},
volume = {85},
publisher = {BMJ},
month = {nov},
url = {https://doi.org/10.1136/jnnp-2013-306465},
number = {7},
pages = {716--720},
doi = {10.1136/jnnp-2013-306465}
}
MLA
Cite this
MLA Copy
Hedegard, E., et al. “Complications to invasive epilepsy surgery workup with subdural and depth electrodes: a prospective population-based observational study.” Journal of Neurology, Neurosurgery and Psychiatry, vol. 85, no. 7, Nov. 2013, pp. 716-720. https://doi.org/10.1136/jnnp-2013-306465.
Found error?