Aromatic fluorination with xenon difluoride: L -3,4-dihydroxy-6-fluoro-phenylalanine
Publication type: Journal Article
Publication date: 1980-07-15
scimago Q3
wos Q4
SJR: 0.254
CiteScore: 2.0
Impact factor: 1.0
ISSN: 00084042, 14803291
DOI:
10.1139/v80-228
General Chemistry
Catalysis
Organic Chemistry
Abstract
L-3-Methoxy-4-hydroxyphenylalanine was fluorinated directly with XeF2 in CH2Cl2 at −60 °C invacuo. After hydrolysis with 48% aqueous HBr, L-6-fluorodopa was obtained. The yield, based on XeF2, was 25%. This reaction might be applied when chiral biomolecules are to be tagged with fluorine-18.
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43
Total citations:
43
Citations from 2025:
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MLA
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GOST
Copy
Firnau G. et al. Aromatic fluorination with xenon difluoride: L-3,4-dihydroxy-6-fluoro-phenylalanine // Canadian Journal of Chemistry. 1980. Vol. 58. No. 14. pp. 1449-1450.
GOST all authors (up to 50)
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Firnau G., Chirakal R., Sood S., Garnett S. Aromatic fluorination with xenon difluoride: L-3,4-dihydroxy-6-fluoro-phenylalanine // Canadian Journal of Chemistry. 1980. Vol. 58. No. 14. pp. 1449-1450.
Cite this
RIS
Copy
TY - JOUR
DO - 10.1139/v80-228
UR - https://doi.org/10.1139/v80-228
TI - Aromatic fluorination with xenon difluoride: L-3,4-dihydroxy-6-fluoro-phenylalanine
T2 - Canadian Journal of Chemistry
AU - Firnau, Gunter
AU - Chirakal, Raman
AU - Sood, Sudesh
AU - Garnett, Stephen
PY - 1980
DA - 1980/07/15
PB - Canadian Science Publishing
SP - 1449-1450
IS - 14
VL - 58
SN - 0008-4042
SN - 1480-3291
ER -
Cite this
BibTex (up to 50 authors)
Copy
@article{1980_Firnau,
author = {Gunter Firnau and Raman Chirakal and Sudesh Sood and Stephen Garnett},
title = {Aromatic fluorination with xenon difluoride: L-3,4-dihydroxy-6-fluoro-phenylalanine},
journal = {Canadian Journal of Chemistry},
year = {1980},
volume = {58},
publisher = {Canadian Science Publishing},
month = {jul},
url = {https://doi.org/10.1139/v80-228},
number = {14},
pages = {1449--1450},
doi = {10.1139/v80-228}
}
Cite this
MLA
Copy
Firnau, Gunter, et al. “Aromatic fluorination with xenon difluoride: L-3,4-dihydroxy-6-fluoro-phenylalanine.” Canadian Journal of Chemistry, vol. 58, no. 14, Jul. 1980, pp. 1449-1450. https://doi.org/10.1139/v80-228.