Review—Non-Enzymatic Hydrogen Peroxide Electrochemical Sensors Based on Reduced Graphene Oxide

The determination of hydrogen peroxide (H₂O₂) plays a crucial role in many industrial applications as well as clinical diagnoses. Electrochemical sensing techniques can provide a rapid, accurate, and simple approach to determine the level of hydrogen peroxide accurately. Recently, reduced graphene oxide (rGO) has been employed extensively to develop amperometric sensors for sensitive and selective detection of H₂O₂ because of its good catalytic activity, mass scalability, and cost-effectiveness. During the past decade, various reduction methods have been used to produce rGO for electrochemical sensing applications. Besides, these electrodes have been modified with functional materials to improve the response of the sensors. Depending on the used materials, characteristics and sensitivity of the sensors varied a lot. Also, the production method of rGO affects the performance of the electrochemical sensor and needs to be taken into account to correlate the results from the sensor with the physical and chemical properties of the sensing material. This article provides an insightful overview of the utilization of rGO in the developments of enzyme-free H₂O₂ electrochemical sensors. This review includes the recent advances in the area from both rGO production method and electrocatalyst performance. Also, the challenges and prospects were discussed in this review.