International Journal of Molecular Imaging, volume 2016, pages 1-5

A Pilot Study of 18F-FLT PET/CT in Pediatric Lymphoma

Danny L. Costantini ^{1, 2}

Reza Vali ^{1, 2}

Susan McQuattie ²

Jeffrey Chan ²

Angela Punnett ³

Shiela Weitzman ³

Amer Shammas ^{1, 2}

MARTIN CHARRON ^{1, 2}

Hide authors affiliations

Department of Medical Imaging, University of Toronto, 263 McCaul Street, 4th Floor, Toronto, ON, Canada M5T 1W7 |

Department of Diagnostic Imaging, Hospital for Sick Children, 555 University Avenue, Toronto, ON, Canada M5G 1X8 |

Department of Pediatrics, Hospital for Sick Children, 555 University Avenue, Toronto, ON, Canada M5G 1X8 |

Publication type: Journal Article

Publication date: 2016-05-26

Hindawi Limited

Journal: International Journal of Molecular Imaging

SJR: —

CiteScore: —

Impact factor: —

ISSN: 20901712, 20901720

DOI: 10.1155/2016/6045894

Copy DOI

PubMed ID: 27313888

Radiology, Nuclear Medicine and imaging

Abstract

We performed an observational pilot study of 18F-FLT PET/CT in pediatric lymphoma. Eight patients with equivocal 18F-FDG PET/CT underwent imaging with 18F-FLT PET/CT. No immediate adverse reactions to 18F-FLT were observed. Compared to 18F-FDG, 18F-FLT uptake was significantly higher in bone marrow and liver (18F-FLT SUV 8.6±0.6 and 5.0±0.3, versus 18F-FDG SUV 1.9±0.1 and 3.4±0.7, resp., p<0.05). In total, 15 lesions were evaluated with average 18F-FDG and 18F-FLT SUVs of 2.6±0.1 and 2.0±0.4, respectively. Nonspecific uptake in reactive lymph nodes and thymus was observed. Future studies to assess the clinical utility of 18F-FLT PET/CT in pediatric lymphoma are planned.

Found

	1
American Journal of Roentgenology	American Journal of Roentgenology, 1, 14.29% American Journal of Roentgenology 1 publication, 14.29%
Nature Protocols	Nature Protocols, 1, 14.29% Nature Protocols 1 publication, 14.29%
PET Clinics	PET Clinics, 1, 14.29% PET Clinics 1 publication, 14.29%
Magnetic Resonance Imaging Clinics of North America	Magnetic Resonance Imaging Clinics of North America, 1, 14.29% Magnetic Resonance Imaging Clinics of North America 1 publication, 14.29%
Pediatric Blood and Cancer	Pediatric Blood and Cancer, 1, 14.29% Pediatric Blood and Cancer 1 publication, 14.29%
EJC Paediatric Oncology	EJC Paediatric Oncology, 1, 14.29% EJC Paediatric Oncology 1 publication, 14.29%
	1

	1 2 3
Elsevier	Elsevier, 3, 42.86% Elsevier 3 publications, 42.86%
American Roentgen Ray Society	American Roentgen Ray Society, 1, 14.29% American Roentgen Ray Society 1 publication, 14.29%
Springer Nature	Springer Nature, 1, 14.29% Springer Nature 1 publication, 14.29%
Wiley	Wiley, 1, 14.29% Wiley 1 publication, 14.29%
	1 2 3

Are you a researcher?

Create a profile to get free access to personal recommendations for colleagues and new articles.

Publication PDF

Metrics

Cite this

GOST | RIS | BibTex

Found error?

Publisher

Hindawi Limited

Journal

International Journal of Molecular Imaging

SJR

—

CiteScore

—

Impact factor

—

ISSN

20901712 (Print)

20901720 (Electronic)

A Pilot Study of 18F-FLT PET/CT in Pediatric Lymphoma

Top-30

Journals

Publishers

Are you a researcher?