S. Karger AG
Chemotherapy
,  volume 38 ,  issue 1 ,  pages 74-76

Netilmicin plus Ceftriaxone versus Amikacin plus Ceftriaxone in the Treatment of Infections in Granulocytopenic Patients

Publication type: Journal Article
Publication date: 1992-01-01
S. Karger AG
scimago Q3
wos Q3
SJR: 0.510
CiteScore: 4.0
Impact factor: 1.7
ISSN: 00093157, 14219794, 21677700
DOI:  10.1159/000238944
PubMed ID:  1618007
Drug Discovery
Oncology
General Medicine
Pharmacology
Infectious Diseases
Pharmacology (medical)
Abstract
For the treatment of febrile episodes in granulocytopenic cancer patients, a combination of bactericidal and intravenously administered broad spectrum agents is recommended. An aminoglycoside plus a β-lactame (piperacillin, azlocillin or IIIrd generation cephalosporins) are the drugs of first choice in an empiric approach. Because of frequent parenteral interventions (e.g. catheters, cannulations) in thrombopenic patients with multifactorial immunosuppression, we consider the application of once daily drugs, such as ceftriaxone, netilmicin or amikacin. For single dose treatment (1st day two applications), we used ceftriaxone in combination with netilmicin or amikacin as the first approach and retrospectively evaluated 47 patients for efficacy and safety.

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Krčméry, Jr. V. et al. Netilmicin plus Ceftriaxone versus Amikacin plus Ceftriaxone in the Treatment of Infections in Granulocytopenic Patients // Chemotherapy. 1992. Vol. 38. No. 1. pp. 74-76.
GOST all authors (up to 50) Copy
Krčméry, Jr. V., Koza I., Mardiak J., Fuchsberger P., Špánik S., Trupl J., Horníková M., Kusenda Z., Šufliarsky J., Švec J. G. Netilmicin plus Ceftriaxone versus Amikacin plus Ceftriaxone in the Treatment of Infections in Granulocytopenic Patients // Chemotherapy. 1992. Vol. 38. No. 1. pp. 74-76.
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RIS Copy
TY - JOUR
DO - 10.1159/000238944
UR - https://www.karger.com/Article/FullText/238944
TI - Netilmicin plus Ceftriaxone versus Amikacin plus Ceftriaxone in the Treatment of Infections in Granulocytopenic Patients
T2 - Chemotherapy
AU - Krčméry, Jr., V.
AU - Koza, I.
AU - Mardiak, J.
AU - Fuchsberger, P.
AU - Špánik, S.
AU - Trupl, J
AU - Horníková, M.
AU - Kusenda, Z.
AU - Šufliarsky, J.
AU - Švec, Jan G.
PY - 1992
DA - 1992/01/01
PB - S. Karger AG
SP - 74-76
IS - 1
VL - 38
PMID - 1618007
SN - 0009-3157
SN - 1421-9794
SN - 2167-7700
ER -
BibTex |
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BibTex (up to 50 authors) Copy
@article{1992_Krčméry, Jr.,
author = {V. Krčméry, Jr. and I. Koza and J. Mardiak and P. Fuchsberger and S. Špánik and J Trupl and M. Horníková and Z. Kusenda and J. Šufliarsky and Jan G. Švec},
title = {Netilmicin plus Ceftriaxone versus Amikacin plus Ceftriaxone in the Treatment of Infections in Granulocytopenic Patients},
journal = {Chemotherapy},
year = {1992},
volume = {38},
publisher = {S. Karger AG},
month = {jan},
url = {https://www.karger.com/Article/FullText/238944},
number = {1},
pages = {74--76},
doi = {10.1159/000238944}
}
MLA
Cite this
MLA Copy
Krčméry, Jr., V., et al. “Netilmicin plus Ceftriaxone versus Amikacin plus Ceftriaxone in the Treatment of Infections in Granulocytopenic Patients.” Chemotherapy, vol. 38, no. 1, Jan. 1992, pp. 74-76. https://www.karger.com/Article/FullText/238944.