Skin Pharmacology and Physiology, volume 17, issue 5, pages 232-237

Ectoin: An Effective Natural Substance to Prevent UVA-Induced Premature Photoaging

J. Buenger ¹

H. Driller ²

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Merck KGaA, Pigments Cosmetics Actives, Business Unit Cosmetics, Research and Development, Darmstadt, Germany. |

Merck KGaA, Pigments Cosmetics Actives, Business Unit Cosmetics, Research and Development, Darmstadt, Germany |

Publication type: Journal Article

Publication date: 2004-09-24

S. Karger AG

Journal: Skin Pharmacology and Physiology

scimago Q2

SJR: 0.623

CiteScore: 5.2

Impact factor: 2.8

ISSN: 16605527, 16605535

DOI: 10.1159/000080216

Copy DOI

PubMed ID: 15452409

General Medicine

Pharmacology

Physiology

Dermatology

Abstract

With the help of a new ‘UVA stress model’, it was shown that Ectoin protects the skin from the effects of UVA-induced cell damage in a number of different ways. Using cell cultures, high-performance thin-layer chromatography, gel electrophoresis mobility shift assays, reverse transcriptase polymerase chain reaction, ion exchange chromatography and UV spectroscopy, it was demonstrated that the UVA-induced second messenger release, transcription factor AP-2 activation, intercellular adhesion molecule-1 expression and mitochondrial DNA mutation could be prevented. The results obtained clearly demonstrate that Ectoin counteracts the effects of UVA-induced and accelerated skin aging at different cell levels.

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16 Field Citation Ratio

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Buenger J., Driller H. Ectoin: An Effective Natural Substance to Prevent UVA-Induced Premature Photoaging // Skin Pharmacology and Physiology. 2004. Vol. 17. No. 5. pp. 232-237.

GOST all authors (up to 50) Copy

Buenger J., Driller H. Ectoin: An Effective Natural Substance to Prevent UVA-Induced Premature Photoaging // Skin Pharmacology and Physiology. 2004. Vol. 17. No. 5. pp. 232-237.

RIS |

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RIS Copy

TY - JOUR

DO - 10.1159/000080216

UR - https://www.karger.com/Article/FullText/80216

TI - Ectoin: An Effective Natural Substance to Prevent UVA-Induced Premature Photoaging

T2 - Skin Pharmacology and Physiology

AU - Buenger, J.

AU - Driller, H.

PY - 2004

DA - 2004/09/24

PB - S. Karger AG

SP - 232-237

IS - 5

VL - 17

PMID - 15452409

SN - 1660-5527

SN - 1660-5535

ER -

BibTex |

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BibTex (up to 50 authors) Copy

@article{2004_Buenger,

author = {J. Buenger and H. Driller},

title = {Ectoin: An Effective Natural Substance to Prevent UVA-Induced Premature Photoaging},

journal = {Skin Pharmacology and Physiology},

year = {2004},

volume = {17},

publisher = {S. Karger AG},

month = {sep},

url = {https://www.karger.com/Article/FullText/80216},

number = {5},

pages = {232--237},

doi = {10.1159/000080216}

}

MLA

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MLA Copy

Buenger, J., et al. “Ectoin: An Effective Natural Substance to Prevent UVA-Induced Premature Photoaging.” Skin Pharmacology and Physiology, vol. 17, no. 5, Sep. 2004, pp. 232-237. https://www.karger.com/Article/FullText/80216.

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Publisher

S. Karger AG

Journal

Skin Pharmacology and Physiology

scimago Q2

SJR

0.623

CiteScore

5.2

Impact factor

2.8

ISSN

16605527 (Print)

16605535 (Electronic)