SAGE
European Journal of Ophthalmology
,  volume 35 ,  issue 3

Faricimab efficacy in a poorly responsive case of Polypoidal Choroidal Vasculopathy (PCV): A case report

Publication type: Journal Article
Publication date: 2025-02-12
SAGE
scimago Q2
wos Q3
SJR: 0.647
CiteScore: 3.9
Impact factor: 1.4
ISSN: 11206721, 17246016
Abstract
Purpose

To evaluate anatomical and functional outcomes of Faricimab therapy on a case of polypoidal choroidal vasculopathy (PCV) refractory to previous treatments.

Major findings

A 56-year-old patient with PCV presenting with a large pigment epithelial detachment (PED) showed best-corrected visual acuity (BCVA) improvement, subretinal fluid (SRF) reduction and PED height reduction at 2 months follow up after a loading phase of 4 monthly Faricimab injections. The patient had previously undergone Aflibercept, Brolucizumab and photodynamic therapy (PDT) treatments with a suboptimal response.

Conclusion

Despite Faricimab proving itself as an efficient alternative in a case of PCV poorly responsive to previous treatments, definite evidence still needs to be confirmed in larger studies.

Found 

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Rizzo C. et al. Faricimab efficacy in a poorly responsive case of Polypoidal Choroidal Vasculopathy (PCV): A case report // European Journal of Ophthalmology. 2025. Vol. 35. No. 3.
GOST all authors (up to 50) Copy
Rizzo C., Savastano M. C., Kilian R., Rizzo S. Faricimab efficacy in a poorly responsive case of Polypoidal Choroidal Vasculopathy (PCV): A case report // European Journal of Ophthalmology. 2025. Vol. 35. No. 3.
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RIS Copy
TY - JOUR
DO - 10.1177/11206721241310629
UR - https://journals.sagepub.com/doi/10.1177/11206721241310629
TI - Faricimab efficacy in a poorly responsive case of Polypoidal Choroidal Vasculopathy (PCV): A case report
T2 - European Journal of Ophthalmology
AU - Rizzo, Clara
AU - Savastano, Maria Cristina
AU - Kilian, Raphael
AU - Rizzo, Stanislao
PY - 2025
DA - 2025/02/12
PB - SAGE
IS - 3
VL - 35
SN - 1120-6721
SN - 1724-6016
ER -
BibTex
Cite this
BibTex (up to 50 authors) Copy
@article{2025_Rizzo,
author = {Clara Rizzo and Maria Cristina Savastano and Raphael Kilian and Stanislao Rizzo},
title = {Faricimab efficacy in a poorly responsive case of Polypoidal Choroidal Vasculopathy (PCV): A case report},
journal = {European Journal of Ophthalmology},
year = {2025},
volume = {35},
publisher = {SAGE},
month = {feb},
url = {https://journals.sagepub.com/doi/10.1177/11206721241310629},
number = {3},
doi = {10.1177/11206721241310629}
}