Imaging Derived Holograms Improve Surgical Outcome in Inexperienced Surgeons: A Meta-Analysis

Andrea Demeco 1
, 
Francesco Renzi 1
, 
Antonio Frizziero 2
, 
Stefano Palermi 3
, 
Antonello Salerno 1
, 
Ruben Foresti 1
, 
Chiara Martini 4
, 
Cosimo Costantino 1
1
 
2
 
Department of Medicine and Surgery, ASST “Gaetano Pini” CTO, Milano, Italy | 
3
 
4
 
Publication type: Journal Article
Publication date: 2025-03-18
SAGE
scimago Q2
wos Q2
SJR: 0.420
CiteScore: 2.8
Impact factor: 1.6
ISSN: 15533506, 15533514
Abstract
Background

Mixed reality (MR) is an emerging technology that has been employed in medicine, providing a holographic representation of patient anatomy.

Purpose

The aim of this review is to examine the use of imaging-derived holograms in the management of musculoskeletal conditions.

Research Desing

A literature search was performed on PubMed, Embase, Web of Science, Scopus, and Google Scholar up to June 2023, a total of 31 studies were included. A random-effects model was employed for the meta-analysis.

Results

MR has been extensively used in orthopedic surgery, spinal surgery, and interventional procedures for pain management. A 3D model is derived from DICOM images and superimposed on the surgical field. The procedure’s accuracy has yielded remarkable results, especially for operators with less surgical experience. Furthermore, this technology minimises the need for intra-procedure imaging, thus reducing radiation exposure.

Conclusion

The meta-analysis showed an impact of MR in reducing operatory time and improving inexperienced surgeons’ accuracy.

Found 
Found 

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Demeco A. et al. Imaging Derived Holograms Improve Surgical Outcome in Inexperienced Surgeons: A Meta-Analysis // Surgical Innovation. 2025.
GOST all authors (up to 50) Copy
Demeco A., Renzi F., Frizziero A., Palermi S., Salerno A., Foresti R., Martini C., Costantino C. Imaging Derived Holograms Improve Surgical Outcome in Inexperienced Surgeons: A Meta-Analysis // Surgical Innovation. 2025.
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RIS Copy
TY - JOUR
DO - 10.1177/15533506251325351
UR - https://journals.sagepub.com/doi/10.1177/15533506251325351
TI - Imaging Derived Holograms Improve Surgical Outcome in Inexperienced Surgeons: A Meta-Analysis
T2 - Surgical Innovation
AU - Demeco, Andrea
AU - Renzi, Francesco
AU - Frizziero, Antonio
AU - Palermi, Stefano
AU - Salerno, Antonello
AU - Foresti, Ruben
AU - Martini, Chiara
AU - Costantino, Cosimo
PY - 2025
DA - 2025/03/18
PB - SAGE
SN - 1553-3506
SN - 1553-3514
ER -
BibTex
Cite this
BibTex (up to 50 authors) Copy
@article{2025_Demeco,
author = {Andrea Demeco and Francesco Renzi and Antonio Frizziero and Stefano Palermi and Antonello Salerno and Ruben Foresti and Chiara Martini and Cosimo Costantino},
title = {Imaging Derived Holograms Improve Surgical Outcome in Inexperienced Surgeons: A Meta-Analysis},
journal = {Surgical Innovation},
year = {2025},
publisher = {SAGE},
month = {mar},
url = {https://journals.sagepub.com/doi/10.1177/15533506251325351},
doi = {10.1177/15533506251325351}
}